Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281765261> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4281765261 endingPage "A5" @default.
- W4281765261 startingPage "A5.2" @default.
- W4281765261 abstract "Introduction The delayed-release dimethyl fumarate (DMF) label recommends use during pregnancy only if potential benefit justifies the potential risk. Given limited pregnancy data, United Kingdom (UK) and Ireland are enrolling DMF-exposed pregnant women into an ongoing international registry assessing pregnancy outcomes. Pregnancies end in live birth (62%), abortion (22%), and fetal loss (16%) in general, with similar rates in MS patients. Methods Pregnant women with MS exposed to DMF since the first day of their last menstrual period prior to conception/during pregnancy were included. The UK/Ireland Coordinating Centres liaise directly with patients and HCPs. Results As of April 2019, 263 patients (14 patients from UK/Ireland) were enrolled. Of the 214 pregnancy outcomes (12 UK/Ireland) reported to date, 197(92%) were live births (12 UK/Ireland) and 17(8%) foetal loss. Of infants with known gestational age (n=197), 176(89%) births were full-term (12 UK/Ireland) and 18(9%) premature (<37 weeks). There were 16 spontaneous abortions (1 ectopic pregnancy), and 1 foetal death at ≥28 weeks of gestation. No molar pregnancies or infant or maternal deaths were reported. Seven(4%) infants (1 UK/Ireland) had confirmed birth defects. Conclusion No safety signal was observed, consistent with MS and general populations. Support: Biogen; disclosures detailed on poster. david.rog@srft.nhs.uk" @default.
- W4281765261 created "2022-06-13" @default.
- W4281765261 creator A5039683609 @default.
- W4281765261 creator A5043996334 @default.
- W4281765261 creator A5063554058 @default.
- W4281765261 creator A5068628840 @default.
- W4281765261 creator A5074453046 @default.
- W4281765261 creator A5078988597 @default.
- W4281765261 date "2022-05-27" @default.
- W4281765261 modified "2023-10-16" @default.
- W4281765261 title "Pregnancy outcomes in a dimethyl fumarate exposure registry" @default.
- W4281765261 doi "https://doi.org/10.1136/jnnp-2022-abn.14" @default.
- W4281765261 hasPublicationYear "2022" @default.
- W4281765261 type Work @default.
- W4281765261 citedByCount "0" @default.
- W4281765261 crossrefType "journal-article" @default.
- W4281765261 hasAuthorship W4281765261A5039683609 @default.
- W4281765261 hasAuthorship W4281765261A5043996334 @default.
- W4281765261 hasAuthorship W4281765261A5063554058 @default.
- W4281765261 hasAuthorship W4281765261A5068628840 @default.
- W4281765261 hasAuthorship W4281765261A5074453046 @default.
- W4281765261 hasAuthorship W4281765261A5078988597 @default.
- W4281765261 hasConcept C131872663 @default.
- W4281765261 hasConcept C187212893 @default.
- W4281765261 hasConcept C2549261 @default.
- W4281765261 hasConcept C2778279030 @default.
- W4281765261 hasConcept C2778642596 @default.
- W4281765261 hasConcept C2779234561 @default.
- W4281765261 hasConcept C29456083 @default.
- W4281765261 hasConcept C3019011928 @default.
- W4281765261 hasConcept C46973012 @default.
- W4281765261 hasConcept C54355233 @default.
- W4281765261 hasConcept C71924100 @default.
- W4281765261 hasConcept C86803240 @default.
- W4281765261 hasConcept C95457728 @default.
- W4281765261 hasConceptScore W4281765261C131872663 @default.
- W4281765261 hasConceptScore W4281765261C187212893 @default.
- W4281765261 hasConceptScore W4281765261C2549261 @default.
- W4281765261 hasConceptScore W4281765261C2778279030 @default.
- W4281765261 hasConceptScore W4281765261C2778642596 @default.
- W4281765261 hasConceptScore W4281765261C2779234561 @default.
- W4281765261 hasConceptScore W4281765261C29456083 @default.
- W4281765261 hasConceptScore W4281765261C3019011928 @default.
- W4281765261 hasConceptScore W4281765261C46973012 @default.
- W4281765261 hasConceptScore W4281765261C54355233 @default.
- W4281765261 hasConceptScore W4281765261C71924100 @default.
- W4281765261 hasConceptScore W4281765261C86803240 @default.
- W4281765261 hasConceptScore W4281765261C95457728 @default.
- W4281765261 hasIssue "6" @default.
- W4281765261 hasLocation W42817652611 @default.
- W4281765261 hasOpenAccess W4281765261 @default.
- W4281765261 hasPrimaryLocation W42817652611 @default.
- W4281765261 hasRelatedWork W2046842812 @default.
- W4281765261 hasRelatedWork W2074469795 @default.
- W4281765261 hasRelatedWork W2131192218 @default.
- W4281765261 hasRelatedWork W2157816811 @default.
- W4281765261 hasRelatedWork W2189483303 @default.
- W4281765261 hasRelatedWork W2364824411 @default.
- W4281765261 hasRelatedWork W2401739700 @default.
- W4281765261 hasRelatedWork W2404744075 @default.
- W4281765261 hasRelatedWork W4302337340 @default.
- W4281765261 hasRelatedWork W2407069984 @default.
- W4281765261 hasVolume "93" @default.
- W4281765261 isParatext "false" @default.
- W4281765261 isRetracted "false" @default.
- W4281765261 workType "article" @default.