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• W4281772408 startingPage "789" @default.
• W4281772408 abstract "Introduction Chemical space is a general conceptual framework that addresses the diversity of molecules and it has various applications. Moreover, chemical space is a cornerstone of chemoinformatics. In response to the increase in the set of chemical compounds in databases, generators of chemical structures, and tools to calculate molecular descriptors, novel approaches to generate visual representations of chemical space are emerging and evolving.Areas covered The current state of chemical space in drug design and discovery is reviewed. The topics discussed herein include advances for efficient navigation in chemical space, the use of this concept in assessing the diversity of different data sets, exploring structure-property/activity relationships for one or multiple endpoints, and compound library design. Recent advances in methodologies for generating visual representations of chemical space have been highlighted, thereby emphasizing open-source methods.Expert opinion Quantitative and qualitative generation and analysis of chemical space require novel approaches for handling the increasing number of molecules and their information available in chemical databases (including emerging ultra-large libraries). Chemical space is a conceptual framework that goes beyond visual representation in low dimensions. However, the graphical representation of chemical space has several practical applications in drug discovery and beyond." @default.
• W4281772408 created "2022-06-13" @default.
• W4281772408 creator A5033903994 @default.
• W4281772408 creator A5086421148 @default.
• W4281772408 date "2022-06-05" @default.
• W4281772408 modified "2023-09-30" @default.
• W4281772408 title "Approaches for enhancing the analysis of chemical space for drug discovery" @default.
• W4281772408 cites W1597224949 @default.
• W4281772408 cites W1754042689 @default.
• W4281772408 cites W1971527053 @default.
• W4281772408 cites W1971849220 @default.
• W4281772408 cites W1972821149 @default.
• W4281772408 cites W1988037271 @default.
• W4281772408 cites W1993133483 @default.
• W4281772408 cites W2001883493 @default.
• W4281772408 cites W2010453137 @default.
• W4281772408 cites W2017254234 @default.
• W4281772408 cites W2020859943 @default.
• W4281772408 cites W2025948031 @default.
• W4281772408 cites W2031913739 @default.
• W4281772408 cites W2061843861 @default.
• W4281772408 cites W2062450879 @default.
• W4281772408 cites W2071796262 @default.
• W4281772408 cites W2078295062 @default.
• W4281772408 cites W2104766360 @default.
• W4281772408 cites W2107636931 @default.
• W4281772408 cites W2110791536 @default.
• W4281772408 cites W2124234891 @default.
• W4281772408 cites W2125426232 @default.
• W4281772408 cites W2134648236 @default.
• W4281772408 cites W2167820873 @default.
• W4281772408 cites W2169599226 @default.
• W4281772408 cites W2179066627 @default.
• W4281772408 cites W2200017991 @default.
• W4281772408 cites W2297121650 @default.
• W4281772408 cites W2486654687 @default.
• W4281772408 cites W2519454444 @default.
• W4281772408 cites W2584785513 @default.
• W4281772408 cites W2734325591 @default.
• W4281772408 cites W2766403465 @default.
• W4281772408 cites W2783084500 @default.
• W4281772408 cites W2804691416 @default.
• W4281772408 cites W2810270980 @default.
• W4281772408 cites W2889555425 @default.
• W4281772408 cites W2892099068 @default.
• W4281772408 cites W2900090807 @default.
• W4281772408 cites W2912328818 @default.
• W4281772408 cites W2919880471 @default.
• W4281772408 cites W2920995682 @default.
• W4281772408 cites W2925830236 @default.
• W4281772408 cites W2945551948 @default.
• W4281772408 cites W2953128081 @default.
• W4281772408 cites W2956961449 @default.
• W4281772408 cites W2962222595 @default.
• W4281772408 cites W2969595198 @default.
• W4281772408 cites W2991736596 @default.
• W4281772408 cites W2997728144 @default.
• W4281772408 cites W2998031109 @default.
• W4281772408 cites W3004306163 @default.
• W4281772408 cites W3008588639 @default.
• W4281772408 cites W3009586793 @default.
• W4281772408 cites W3011366455 @default.
• W4281772408 cites W3013657235 @default.
• W4281772408 cites W3022691040 @default.
• W4281772408 cites W3023036485 @default.
• W4281772408 cites W3023204497 @default.
• W4281772408 cites W3033617175 @default.
• W4281772408 cites W3035302862 @default.
• W4281772408 cites W3037832460 @default.
• W4281772408 cites W3045647619 @default.
• W4281772408 cites W3045928028 @default.
• W4281772408 cites W3046264932 @default.
• W4281772408 cites W3089139172 @default.
• W4281772408 cites W3094640617 @default.
• W4281772408 cites W3098269892 @default.
• W4281772408 cites W3099551742 @default.
• W4281772408 cites W3101498208 @default.
• W4281772408 cites W3112559629 @default.
• W4281772408 cites W3114423549 @default.
• W4281772408 cites W3118695441 @default.
• W4281772408 cites W3119952098 @default.
• W4281772408 cites W3121164892 @default.
• W4281772408 cites W3125778162 @default.
• W4281772408 cites W3126326305 @default.
• W4281772408 cites W3128426563 @default.
• W4281772408 cites W3128779876 @default.
• W4281772408 cites W3143491409 @default.
• W4281772408 cites W3158331815 @default.
• W4281772408 cites W3158985051 @default.
• W4281772408 cites W3165171933 @default.
• W4281772408 cites W3171010532 @default.
• W4281772408 cites W3173770342 @default.
• W4281772408 cites W3195472651 @default.
• W4281772408 cites W3209805961 @default.
• W4281772408 cites W3212363465 @default.
• W4281772408 cites W3216008944 @default.
• W4281772408 cites W4225932677 @default.
• W4281772408 cites W4226062292 @default.

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