FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281775298> ?p ?o ?g. }

• W4281775298 abstract "Estimating the required sample size is crucial when developing and validating clinical prediction models. However, there is no consensus about how to determine the sample size in such a setting. Here, the goal was to compare available methods to define a practical solution to sample size estimation for clinical predictive models, as applied to Horizon 2020 PRIMAGE as a case study.Three different methods (Riley's; rule of thumb with 10 and 5 events per predictor) were employed to calculate the sample size required to develop predictive models to analyse the variation in sample size as a function of different parameters. Subsequently, the sample size for model validation was also estimated.To develop reliable predictive models, 1397 neuroblastoma patients are required, 1060 high-risk neuroblastoma patients and 1345 diffuse intrinsic pontine glioma (DIPG) patients. This sample size can be lowered by reducing the number of variables included in the model, by including direct measures of the outcome to be predicted and/or by increasing the follow-up period. For model validation, the estimated sample size resulted to be 326 patients for neuroblastoma, 246 for high-risk neuroblastoma, and 592 for DIPG.Given the variability of the different sample sizes obtained, we recommend using methods based on epidemiological data and the nature of the results, as the results are tailored to the specific clinical problem. In addition, sample size can be reduced by lowering the number of parameter predictors, by including direct measures of the outcome of interest." @default.
• W4281775298 created "2022-06-13" @default.
• W4281775298 creator A5000865121 @default.
• W4281775298 creator A5002369122 @default.
• W4281775298 creator A5009626793 @default.
• W4281775298 creator A5018707123 @default.
• W4281775298 creator A5032742509 @default.
• W4281775298 creator A5072387429 @default.
• W4281775298 creator A5076110855 @default.
• W4281775298 date "2022-06-01" @default.
• W4281775298 modified "2023-10-18" @default.
• W4281775298 title "A practical solution to estimate the sample size required for clinical prediction models generated from observational research on data" @default.
• W4281775298 cites W1479733172 @default.
• W4281775298 cites W1982245010 @default.
• W4281775298 cites W2008706768 @default.
• W4281775298 cites W2016177128 @default.
• W4281775298 cites W2037668591 @default.
• W4281775298 cites W2049509720 @default.
• W4281775298 cites W2054953567 @default.
• W4281775298 cites W2060260083 @default.
• W4281775298 cites W2065301690 @default.
• W4281775298 cites W2100697007 @default.
• W4281775298 cites W2110788947 @default.
• W4281775298 cites W2122892545 @default.
• W4281775298 cites W2123162799 @default.
• W4281775298 cites W2127478952 @default.
• W4281775298 cites W2130373985 @default.
• W4281775298 cites W2191179271 @default.
• W4281775298 cites W2296761362 @default.
• W4281775298 cites W2518769893 @default.
• W4281775298 cites W2595557058 @default.
• W4281775298 cites W2596627175 @default.
• W4281775298 cites W2884065486 @default.
• W4281775298 cites W2896476100 @default.
• W4281775298 cites W2898559532 @default.
• W4281775298 cites W2933306564 @default.
• W4281775298 cites W2973179191 @default.
• W4281775298 cites W2990742598 @default.
• W4281775298 cites W3012413426 @default.
• W4281775298 cites W3014304753 @default.
• W4281775298 cites W3124405041 @default.
• W4281775298 cites W3125100459 @default.
• W4281775298 cites W3135092238 @default.
• W4281775298 cites W3166664106 @default.
• W4281775298 cites W3175276305 @default.
• W4281775298 cites W3179960106 @default.
• W4281775298 cites W4237653395 @default.
• W4281775298 doi "https://doi.org/10.1186/s41747-022-00276-y" @default.
• W4281775298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35641659" @default.
• W4281775298 hasPublicationYear "2022" @default.
• W4281775298 type Work @default.
• W4281775298 citedByCount "6" @default.
• W4281775298 countsByYear W42817752982022 @default.
• W4281775298 countsByYear W42817752982023 @default.
• W4281775298 crossrefType "journal-article" @default.
• W4281775298 hasAuthorship W4281775298A5000865121 @default.
• W4281775298 hasAuthorship W4281775298A5002369122 @default.
• W4281775298 hasAuthorship W4281775298A5009626793 @default.
• W4281775298 hasAuthorship W4281775298A5018707123 @default.
• W4281775298 hasAuthorship W4281775298A5032742509 @default.
• W4281775298 hasAuthorship W4281775298A5072387429 @default.
• W4281775298 hasAuthorship W4281775298A5076110855 @default.
• W4281775298 hasBestOaLocation W42817752981 @default.
• W4281775298 hasConcept C105795698 @default.
• W4281775298 hasConcept C129848803 @default.
• W4281775298 hasConcept C185592680 @default.
• W4281775298 hasConcept C198531522 @default.
• W4281775298 hasConcept C33923547 @default.
• W4281775298 hasConcept C43617362 @default.
• W4281775298 hasConcept C45804977 @default.
• W4281775298 hasConcept C71924100 @default.
• W4281775298 hasConceptScore W4281775298C105795698 @default.
• W4281775298 hasConceptScore W4281775298C129848803 @default.
• W4281775298 hasConceptScore W4281775298C185592680 @default.
• W4281775298 hasConceptScore W4281775298C198531522 @default.
• W4281775298 hasConceptScore W4281775298C33923547 @default.
• W4281775298 hasConceptScore W4281775298C43617362 @default.
• W4281775298 hasConceptScore W4281775298C45804977 @default.
• W4281775298 hasConceptScore W4281775298C71924100 @default.
• W4281775298 hasFunder F4320338342 @default.
• W4281775298 hasIssue "1" @default.
• W4281775298 hasLocation W42817752981 @default.
• W4281775298 hasLocation W42817752982 @default.
• W4281775298 hasLocation W42817752983 @default.
• W4281775298 hasLocation W42817752984 @default.
• W4281775298 hasOpenAccess W4281775298 @default.
• W4281775298 hasPrimaryLocation W42817752981 @default.
• W4281775298 hasRelatedWork W1771779360 @default.
• W4281775298 hasRelatedWork W1988747059 @default.
• W4281775298 hasRelatedWork W1993731342 @default.
• W4281775298 hasRelatedWork W2057598446 @default.
• W4281775298 hasRelatedWork W2119095362 @default.
• W4281775298 hasRelatedWork W2172032168 @default.
• W4281775298 hasRelatedWork W2290081135 @default.
• W4281775298 hasRelatedWork W3022782703 @default.
• W4281775298 hasRelatedWork W3210933308 @default.
• W4281775298 hasRelatedWork W871906761 @default.
• W4281775298 hasVolume "6" @default.
• W4281775298 isParatext "false" @default.
• W4281775298 isRetracted "false" @default.

• next