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- W4281779023 abstract "Progressive multifocal leukoencephalopathy may occur in immunosuppressed people and is attributed to John Cunningham virus reactivation. We hereby report a case with progressive multifocal leukoencephalopathy under fingolimod treatment, with characteristic radiological findings of cerebellar involvement, described as “the shrimp sign”. This sign shows high specificity and sensitivity for progressive multifocal leukoencephalopathy, in the right clinical context. In addition, we present the course of the disease and we discuss current and potential future treatment strategies. Given the limited efficacy of current therapeutic approaches, the early identification of progressive multifocal encephalopathy and timely discontinuation of immunosuppressing agents may enable a better outcome of this disease. The “shrimp sign” may enable clinicians to detect this entity early in people at a higher risk." @default.
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- W4281779023 date "2022-01-01" @default.
- W4281779023 modified "2023-09-30" @default.
- W4281779023 title "Shrimp sign in a case of progressive multifocal leukoencephalopathy under fingolimod treatment" @default.
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- W4281779023 doi "https://doi.org/10.1016/j.nerep.2022.100105" @default.
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