FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281788586> ?p ?o ?g. }

• W4281788586 endingPage "2715" @default.
• W4281788586 startingPage "2708" @default.
• W4281788586 abstract "Abstract Background and purpose Hypertension is a risk factor for subarachnoid hemorrhage and is also considered a risk factor for saccular intracranial aneurysm (sIA) formation. However, there is little direct evidence that antihypertensive medication will reduce sIA formation. Methods The impact of antihypertensive medication on de novo sIA formation was studied in an angiographically followed cohort of 1419 patients. Patients were identified from our population‐based Kuopio Intracranial Aneurysm Database, and data on the purchases of antihypertensive medication were obtained from a national registry. Univariate and multivariate analyses were used to investigate the risk factors. Results Of the 966 sIA patients who were prescribed with antihypertensive medication, 841 patients used the medication regularly; 20 of them had de novo sIA. One hundred and twenty‐five patients used the medication irregularly and 12 of them developed de novo sIAs. Four hundred and fifty‐three patients did not use antihypertensive medication even though 27 of them had a diagnosis of hypertension, and 10 of them developed de novo sIAs. In the multivariate analysis antihypertensive medication did not significantly reduce de novo sIA formation (hazard ratio [HR] 1.60, 95% confidence interval [CI] 0.84–3.06). Age at primary diagnosis (HR: 0.95, 95%: CI 0.93–0.98) and smoking history (HR: 5.53, 95% CI: 2.77–11.05) were significant risk factors for de novo sIA formation. Also, irregular usage of antihypertensive medication was a significant risk factor (HR: 3.84, 95% CI: 1.59–9.29) for de novo sIA formation. Conclusions Antihypertensive agents were not associated with a reduction of de novo sIA formation, but irregular use of antihypertensive agents was associated with an increased risk of de novo sIA formation." @default.
• W4281788586 created "2022-06-13" @default.
• W4281788586 creator A5002882158 @default.
• W4281788586 creator A5005975812 @default.
• W4281788586 creator A5014639410 @default.
• W4281788586 creator A5044027307 @default.
• W4281788586 creator A5053834653 @default.
• W4281788586 creator A5058739858 @default.
• W4281788586 creator A5063597374 @default.
• W4281788586 creator A5089841749 @default.
• W4281788586 date "2022-06-16" @default.
• W4281788586 modified "2023-10-14" @default.
• W4281788586 title "Use of antihypertensive medication and formation of de novo intracranial aneurysms" @default.
• W4281788586 cites W1538625344 @default.
• W4281788586 cites W1981887516 @default.
• W4281788586 cites W1993065884 @default.
• W4281788586 cites W2059128100 @default.
• W4281788586 cites W2063887943 @default.
• W4281788586 cites W2079321004 @default.
• W4281788586 cites W2090190388 @default.
• W4281788586 cites W2090896340 @default.
• W4281788586 cites W2104812315 @default.
• W4281788586 cites W2113713760 @default.
• W4281788586 cites W2115176183 @default.
• W4281788586 cites W2133016590 @default.
• W4281788586 cites W2143671723 @default.
• W4281788586 cites W2157021912 @default.
• W4281788586 cites W2163466561 @default.
• W4281788586 cites W2169713883 @default.
• W4281788586 cites W2264344578 @default.
• W4281788586 cites W2315017792 @default.
• W4281788586 cites W2883053061 @default.
• W4281788586 cites W2913112014 @default.
• W4281788586 cites W2955521236 @default.
• W4281788586 cites W4361773820 @default.
• W4281788586 doi "https://doi.org/10.1111/ene.15430" @default.
• W4281788586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35652754" @default.
• W4281788586 hasPublicationYear "2022" @default.
• W4281788586 type Work @default.
• W4281788586 citedByCount "1" @default.
• W4281788586 countsByYear W42817885862023 @default.
• W4281788586 crossrefType "journal-article" @default.
• W4281788586 hasAuthorship W4281788586A5002882158 @default.
• W4281788586 hasAuthorship W4281788586A5005975812 @default.
• W4281788586 hasAuthorship W4281788586A5014639410 @default.
• W4281788586 hasAuthorship W4281788586A5044027307 @default.
• W4281788586 hasAuthorship W4281788586A5053834653 @default.
• W4281788586 hasAuthorship W4281788586A5058739858 @default.
• W4281788586 hasAuthorship W4281788586A5063597374 @default.
• W4281788586 hasAuthorship W4281788586A5089841749 @default.
• W4281788586 hasConcept C126322002 @default.
• W4281788586 hasConcept C141071460 @default.
• W4281788586 hasConcept C144301174 @default.
• W4281788586 hasConcept C207103383 @default.
• W4281788586 hasConcept C2776098176 @default.
• W4281788586 hasConcept C2777736543 @default.
• W4281788586 hasConcept C2780192228 @default.
• W4281788586 hasConcept C38180746 @default.
• W4281788586 hasConcept C44249647 @default.
• W4281788586 hasConcept C50440223 @default.
• W4281788586 hasConcept C71924100 @default.
• W4281788586 hasConcept C72563966 @default.
• W4281788586 hasConcept C84393581 @default.
• W4281788586 hasConceptScore W4281788586C126322002 @default.
• W4281788586 hasConceptScore W4281788586C141071460 @default.
• W4281788586 hasConceptScore W4281788586C144301174 @default.
• W4281788586 hasConceptScore W4281788586C207103383 @default.
• W4281788586 hasConceptScore W4281788586C2776098176 @default.
• W4281788586 hasConceptScore W4281788586C2777736543 @default.
• W4281788586 hasConceptScore W4281788586C2780192228 @default.
• W4281788586 hasConceptScore W4281788586C38180746 @default.
• W4281788586 hasConceptScore W4281788586C44249647 @default.
• W4281788586 hasConceptScore W4281788586C50440223 @default.
• W4281788586 hasConceptScore W4281788586C71924100 @default.
• W4281788586 hasConceptScore W4281788586C72563966 @default.
• W4281788586 hasConceptScore W4281788586C84393581 @default.
• W4281788586 hasFunder F4320310751 @default.
• W4281788586 hasFunder F4320321108 @default.
• W4281788586 hasFunder F4320322356 @default.
• W4281788586 hasFunder F4320322456 @default.
• W4281788586 hasIssue "9" @default.
• W4281788586 hasLocation W42817885861 @default.
• W4281788586 hasLocation W42817885862 @default.
• W4281788586 hasOpenAccess W4281788586 @default.
• W4281788586 hasPrimaryLocation W42817885861 @default.
• W4281788586 hasRelatedWork W2052388110 @default.
• W4281788586 hasRelatedWork W2058520121 @default.
• W4281788586 hasRelatedWork W2100497053 @default.
• W4281788586 hasRelatedWork W2160614002 @default.
• W4281788586 hasRelatedWork W2610246910 @default.
• W4281788586 hasRelatedWork W2770409748 @default.
• W4281788586 hasRelatedWork W2887215952 @default.
• W4281788586 hasRelatedWork W2980395326 @default.
• W4281788586 hasRelatedWork W3032878399 @default.
• W4281788586 hasRelatedWork W4205886179 @default.
• W4281788586 hasVolume "29" @default.
• W4281788586 isParatext "false" @default.
• W4281788586 isRetracted "false" @default.

• next