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- W4281824401 abstract "Successful morphogenesis on the scale of organs or organisms requires strict coordination between the constituent cells whose action on the local scale must be orchestrated accurately to achieve a functional shape on the global scale. We present a theoretical model in which morphogenetic information is encoded only through a locally preferred curvature, but with cell dynamics which simultaneously ensures that these interactions globally achieve morphogenesis and correct cell-neighbor exchanges to avoid cell stretches. This is achieved by a cell-cell interaction potential that drives correct cell intercalation to reorganize the cell sheet dynamically during the deformation processes. We demonstrate morphogenesis of simple three-dimensional shapes and study the effects of fixed cell neighbor connectivity and noisy cell division." @default.
- W4281824401 created "2022-06-13" @default.
- W4281824401 creator A5013570173 @default.
- W4281824401 date "2022-05-31" @default.
- W4281824401 modified "2023-10-14" @default.
- W4281824401 title "Curvature strains as a global orchestrator of morphogenesis" @default.
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- W4281824401 doi "https://doi.org/10.1103/physrevresearch.4.023171" @default.
- W4281824401 hasPublicationYear "2022" @default.
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