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• W4282008608 abstract "Hospitalized patients with systemic autoimmune rheumatic diseases (SARDs) generate high impact in clinical terms. To characterize the study population and estimate risk factors associated with the presence of adverse outcomes in hospitalized patients consulting rheumatology at Clínica Imbanaco between January 2013 and December 2019. We analyzed a historical cohort of hospitalized patients who were evaluated by rheumatology. The population was classified as follows: group 1, patients with new onset diagnosed SARDs; group 2, patients with known diagnosed SARDs; group 3, patients without diagnosed SARDs; and group 4, patients with unconfirmed suspicion of SARDs. A composite adverse outcome was defined if at least one of the following occurred: (1) hospital mortality, (2) admission to the intensive care unit, (3) hospital infection, or (4) readmission. Information was collected from 327 hospitalization events (307 patients). The median age was 48 (34−63) years and 222 (72.3%) were women. The composite adverse outcome occurred in 136 (41.5%) hospitalization events. Group 2 had the highest number of adverse outcomes (61/128; 47.6%). The variables associated with the worst outcomes were cardiovascular diagnosis at admission (OR = 4.63; CI: 1.60−13.43; p = 0.005), longer hospital stay (OR = 1.04; CI: 1.01−1.07; p = 0.005), and a treating specialty other than internal medicine (OR = 2.79; CI: 1.26−6.17; p = 0.011). Male sex (OR = 0.29; CI: 0.12–0.66; p = 0.004), having special health coverage (OR = 0.39; CI: 0.15–.099; p = 0.047), and hemoglobin > 11.4 g/dL (OR = 0.82; CI: 0.69–0.99; p = 0.039) were the factors associated with lower odds of developing the composite outcome. In this historical cohort, the group of patients with known diagnosed SARDs presented a higher number in percentage terms of adverse outcomes. The most frequent adverse outcomes were admission to the ICU and hospital readmission. Los pacientes hospitalizados con enfermedades reumáticas o autoinmunes sistémicas (ERAS) generan gran impacto en términos clínicos. Caracterizar a la población y estimar factores de riesgo asociados con la presencia de desenlaces adversos en pacientes evaluados hospitalariamente por reumatología en la Clínica Imbanaco durante los años 2013–2019. Se analizó una cohorte histórica de pacientes hospitalizados que fueron evaluados por reumatología. La población se clasificó así: grupo 1, pacientes con ERAS diagnosticada de novo; grupo 2, pacientes con ERAS diagnosticada conocida; grupo 3, pacientes sin ERAS diagnosticada; y grupo 4, pacientes con sospecha no confirmada de ERAS. Se definió un desenlace adverso compuesto si se presentó al menos uno de los siguientes casos: (1) mortalidad hospitalaria; (2) ingreso a la unidad de cuidado intensivo; (3) infección intrahospitalaria; (4) reingreso. En un total de 327 eventos de hospitalización (307 pacientes), la mediana de edad fue 48 (34−63) años y 222 (72,3%) fueron mujeres. El desenlace adverso compuesto se presentó en 136 (41,5%) eventos. El grupo 2 tuvo mayor número de desenlaces adversos (61/128; 47,6%). Las variables asociadas con peores resultados fueron: diagnóstico inicial cardiovascular (OR = 4,63; IC: 1,60−13,43; p = 0,005), mayor estancia hospitalaria (OR = 1,04; IC: 1,01−1,07; p = 0,005) y tener una especialidad tratante diferente a medicina interna (OR = 2,79; IC: 1,26−6,17; p = 0,011). El sexo masculino (OR = 0,29; IC: 0,12−0,66; p = 0,004), pertenecer a un régimen especial de salud (OR = 0,39; IC: 0,15−0,99; p = 0,047) y tener hemoglobina >11,4 g/dL (OR = 0,82; IC: 0,69−0,99; p = 0,039) fueron factores asociados con menor oportunidad de desarrollar el desenlace compuesto. En esta cohorte histórica se encontró que porcentualmente el grupo de pacientes con ERAS diagnosticadas conocidas presentó mayor número de desenlaces adversos, entre los que se destacan para el mismo grupo, el ingreso a UCI y el reingreso hospitalario." @default.
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• W4282008608 date "2022-07-01" @default.
• W4282008608 modified "2023-10-03" @default.
• W4282008608 title "Hospital outcomes in patients evaluated by rheumatology in a Colombian historical cohort" @default.
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• W4282008608 doi "https://doi.org/10.1016/j.rcreue.2021.02.003" @default.
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