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- W4282015364 abstract "Vasodilatory compounds have long been used in the treatment of heart failure. Whereas they have mostly been used in the setting of acutely decompensated heart failure, there is evidence to support the use of oral preparations in certain subgroups with chronic heart failure. This chapter explores the current evidence and guidelines for the use of vasodilators in clinical practice, both in the acute and chronic setting; and it examines the potential for novel vasodilatory compounds and possible future directions. Although there remains a compelling physiological basis for the use of vasodilators, lack of robust evidence has led to differing opinions about their use both in acute and chronic heart failure. Much of the difference is due to the difficulties in performing clinical trials, particularly in the acute setting where time-limited interventions and the diverse presentation of patients makes the logistics of studies challenging." @default.
- W4282015364 created "2022-06-13" @default.
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- W4282015364 date "2022-05-01" @default.
- W4282015364 modified "2023-10-14" @default.
- W4282015364 title "Vasodilators" @default.
- W4282015364 doi "https://doi.org/10.1093/med/9780198766223.003.0045" @default.
- W4282015364 hasPublicationYear "2022" @default.
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