FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282022356> ?p ?o ?g. }

• W4282022356 endingPage "100401" @default.
• W4282022356 startingPage "100401" @default.
• W4282022356 abstract "A series of ester and ether bridged compounds bearing the nitro and amino moieties were synthesized and characterized, in order to assess their ability to potentially serve as antibacterial agents against drug resistant bacteria. All the compounds were obtained at considerable yields while characterization techniques confirmed their successful synthesis. Furthermore, their antimicrobial assessments showed that all the compounds exhibited antibacterial activity against the Gram-negative bacterial strains, both Klebsiella pneumoniae and its drug resistant counterpart. On the contrary, they were poorly active against S. aureus and MRSA. According to the MIC data, all the compounds showed activity of 0.22 to 0.24 mM towards MDR-K. pneumoniae which was higher than the 0.13 mM of the control AgSD. As for K. pneumoniae, the nitro derivatives L1 and L4 showed significantly higher MIC of 0.23 and 0.26 mM, respectively; while the amino derivatives L2 and L3 were more active, with MIC values of 0.16 mM that was better than the 0.18 mM of the control AgSD. Finally, the time kill kinetics study showed that L2, L3 and the control AgSD were bacteriostatic, while L1 and L4 initially showed a bactericidal trend towards K. pneumoniae but eventually changed to an exponential growth. However, all the compounds were bactericidal towards MDR- K. pneumoniae." @default.
• W4282022356 created "2022-06-13" @default.
• W4282022356 creator A5005384441 @default.
• W4282022356 creator A5009140233 @default.
• W4282022356 creator A5029428453 @default.
• W4282022356 creator A5044782669 @default.
• W4282022356 creator A5076192107 @default.
• W4282022356 creator A5084757836 @default.
• W4282022356 creator A5086003672 @default.
• W4282022356 creator A5088087175 @default.
• W4282022356 date "2022-01-01" @default.
• W4282022356 modified "2023-10-01" @default.
• W4282022356 title "Synthesis, characterization of nitro or amino substituted pyridyl ligands bridged by an ester or ether bond, and their antibacterial assessment against drug resistant bacteria" @default.
• W4282022356 cites W1970361809 @default.
• W4282022356 cites W1972004713 @default.
• W4282022356 cites W1982346259 @default.
• W4282022356 cites W1999511496 @default.
• W4282022356 cites W2024901091 @default.
• W4282022356 cites W2026598007 @default.
• W4282022356 cites W2074948884 @default.
• W4282022356 cites W2099866342 @default.
• W4282022356 cites W2108638835 @default.
• W4282022356 cites W2119892971 @default.
• W4282022356 cites W2145538324 @default.
• W4282022356 cites W2148756948 @default.
• W4282022356 cites W2157160987 @default.
• W4282022356 cites W2157593067 @default.
• W4282022356 cites W2166845515 @default.
• W4282022356 cites W2722324655 @default.
• W4282022356 cites W2767891136 @default.
• W4282022356 cites W2885402339 @default.
• W4282022356 cites W3011719258 @default.
• W4282022356 cites W3190542935 @default.
• W4282022356 cites W4205856112 @default.
• W4282022356 doi "https://doi.org/10.1016/j.rechem.2022.100401" @default.
• W4282022356 hasPublicationYear "2022" @default.
• W4282022356 type Work @default.
• W4282022356 citedByCount "3" @default.
• W4282022356 countsByYear W42820223562023 @default.
• W4282022356 crossrefType "journal-article" @default.
• W4282022356 hasAuthorship W4282022356A5005384441 @default.
• W4282022356 hasAuthorship W4282022356A5009140233 @default.
• W4282022356 hasAuthorship W4282022356A5029428453 @default.
• W4282022356 hasAuthorship W4282022356A5044782669 @default.
• W4282022356 hasAuthorship W4282022356A5076192107 @default.
• W4282022356 hasAuthorship W4282022356A5084757836 @default.
• W4282022356 hasAuthorship W4282022356A5086003672 @default.
• W4282022356 hasAuthorship W4282022356A5088087175 @default.
• W4282022356 hasBestOaLocation W42820223561 @default.
• W4282022356 hasConcept C104317684 @default.
• W4282022356 hasConcept C176947019 @default.
• W4282022356 hasConcept C178790620 @default.
• W4282022356 hasConcept C185592680 @default.
• W4282022356 hasConcept C2777058267 @default.
• W4282022356 hasConcept C2780104969 @default.
• W4282022356 hasConcept C2780263894 @default.
• W4282022356 hasConcept C2780407432 @default.
• W4282022356 hasConcept C2780639532 @default.
• W4282022356 hasConcept C4937899 @default.
• W4282022356 hasConcept C523546767 @default.
• W4282022356 hasConcept C54355233 @default.
• W4282022356 hasConcept C547475151 @default.
• W4282022356 hasConcept C55493867 @default.
• W4282022356 hasConcept C71240020 @default.
• W4282022356 hasConcept C86803240 @default.
• W4282022356 hasConcept C89423630 @default.
• W4282022356 hasConceptScore W4282022356C104317684 @default.
• W4282022356 hasConceptScore W4282022356C176947019 @default.
• W4282022356 hasConceptScore W4282022356C178790620 @default.
• W4282022356 hasConceptScore W4282022356C185592680 @default.
• W4282022356 hasConceptScore W4282022356C2777058267 @default.
• W4282022356 hasConceptScore W4282022356C2780104969 @default.
• W4282022356 hasConceptScore W4282022356C2780263894 @default.
• W4282022356 hasConceptScore W4282022356C2780407432 @default.
• W4282022356 hasConceptScore W4282022356C2780639532 @default.
• W4282022356 hasConceptScore W4282022356C4937899 @default.
• W4282022356 hasConceptScore W4282022356C523546767 @default.
• W4282022356 hasConceptScore W4282022356C54355233 @default.
• W4282022356 hasConceptScore W4282022356C547475151 @default.
• W4282022356 hasConceptScore W4282022356C55493867 @default.
• W4282022356 hasConceptScore W4282022356C71240020 @default.
• W4282022356 hasConceptScore W4282022356C86803240 @default.
• W4282022356 hasConceptScore W4282022356C89423630 @default.
• W4282022356 hasLocation W42820223561 @default.
• W4282022356 hasLocation W42820223562 @default.
• W4282022356 hasOpenAccess W4282022356 @default.
• W4282022356 hasPrimaryLocation W42820223561 @default.
• W4282022356 hasRelatedWork W116013594 @default.
• W4282022356 hasRelatedWork W2003208180 @default.
• W4282022356 hasRelatedWork W2184157837 @default.
• W4282022356 hasRelatedWork W2336984897 @default.
• W4282022356 hasRelatedWork W2399363405 @default.
• W4282022356 hasRelatedWork W2409709769 @default.
• W4282022356 hasRelatedWork W2619415615 @default.
• W4282022356 hasRelatedWork W2621868777 @default.
• W4282022356 hasRelatedWork W3005684984 @default.
• W4282022356 hasRelatedWork W3041641488 @default.
• W4282022356 hasVolume "4" @default.

• next