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• W4282023109 abstract "Background The pattern of structural brain abnormalities in anorexia nervosa (AN) is still not well understood. While several studies report substantial deficits in gray matter volume and cortical thickness in acutely underweight patients, others find no differences, or even increases in patients compared with healthy control subjects. Recent weight regain before scanning may explain some of this heterogeneity. To clarify the extent, magnitude, and dependencies of gray matter changes in AN, we conducted a prospective, coordinated meta-analysis of multicenter neuroimaging data. Methods We analyzed T1-weighted structural magnetic resonance imaging scans assessed with standardized methods from 685 female patients with AN and 963 female healthy control subjects across 22 sites worldwide. In addition to a case-control comparison, we conducted a 3-group analysis comparing healthy control subjects with acutely underweight AN patients (n = 466) and partially weight-restored patients in treatment (n = 251). Results In AN, reductions in cortical thickness, subcortical volumes, and, to a lesser extent, cortical surface area were sizable (Cohen’s d up to 0.95), widespread, and colocalized with hub regions. Highlighting the effects of undernutrition, these deficits were associated with lower body mass index in the AN sample and were less pronounced in partially weight-restored patients. Conclusions The effect sizes observed for cortical thickness deficits in acute AN are the largest of any psychiatric disorder investigated in the ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis) Consortium to date. These results confirm the importance of considering weight loss and renutrition in biomedical research on AN and underscore the importance of treatment engagement to prevent potentially long-lasting structural brain changes in this population." @default.
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• W4282023109 date "2022-11-01" @default.
• W4282023109 modified "2023-10-18" @default.
• W4282023109 title "Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group" @default.
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• W4282023109 cites W2151130155 @default.
• W4282023109 cites W2155975020 @default.
• W4282023109 cites W2273268644 @default.
• W4282023109 cites W2312672406 @default.
• W4282023109 cites W2397026969 @default.
• W4282023109 cites W2528004326 @default.
• W4282023109 cites W2567586580 @default.
• W4282023109 cites W2605598811 @default.
• W4282023109 cites W2746634570 @default.
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• W4282023109 cites W2803924162 @default.
• W4282023109 cites W2804287612 @default.
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• W4282023109 cites W2889221670 @default.
• W4282023109 cites W2904886331 @default.
• W4282023109 cites W2919457122 @default.
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