FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282024761> ?p ?o ?g. }

• W4282024761 abstract "The management of melanoma patients with metastatic melanoma in the sentinel nodes (SN) is evolving based on the results of trials questioning the impact of completion lymph node dissection (CLND) and demonstrating the efficacy of new adjuvant treatments. In this landscape, new prognostic tools for fine risk stratification are eagerly sought to optimize the therapeutic path of these patients.A retrospective cohort of 2,086 patients treated with CLND after a positive SN biopsy in thirteen Italian Melanoma Centers was reviewed. Overall survival (OS) was the outcome of interest; included independent variables were the following: age, gender, primary melanoma site, Breslow thickness, ulceration, sentinel node tumor burden (SNTB), number of positive SN, non-sentinel lymph nodes (NSN) status. Univariate and multivariate survival analyses were performed using the Cox proportional hazard regression model.The 3-year, 5-year and 10-year OS rates were 79%, 70% and 54%, respectively. At univariate analysis, all variables, except for primary melanoma body site, were found to be statistically significant prognostic factors. Multivariate Cox regression analysis indicated that older age (P < 0.0001), male gender (P = 0.04), increasing Breslow thickness (P < 0.0001), presence of ulceration (P = 0.004), SNTB size (P < 0.0001) and metastatic NSN (P < 0.0001) were independent negative predictors of OS.The above results were utilized to build a nomogram in order to ease the practical implementation of our prognostic model, which might improve treatment personalization." @default.
• W4282024761 created "2022-06-13" @default.
• W4282024761 creator A5000391768 @default.
• W4282024761 creator A5001293319 @default.
• W4282024761 creator A5004401304 @default.
• W4282024761 creator A5005909861 @default.
• W4282024761 creator A5007431288 @default.
• W4282024761 creator A5008166009 @default.
• W4282024761 creator A5010533525 @default.
• W4282024761 creator A5010608336 @default.
• W4282024761 creator A5010831003 @default.
• W4282024761 creator A5011521807 @default.
• W4282024761 creator A5011613484 @default.
• W4282024761 creator A5018536695 @default.
• W4282024761 creator A5020324374 @default.
• W4282024761 creator A5023542650 @default.
• W4282024761 creator A5023633541 @default.
• W4282024761 creator A5024760456 @default.
• W4282024761 creator A5024934865 @default.
• W4282024761 creator A5027952276 @default.
• W4282024761 creator A5028852995 @default.
• W4282024761 creator A5030042462 @default.
• W4282024761 creator A5031267534 @default.
• W4282024761 creator A5032620018 @default.
• W4282024761 creator A5032718904 @default.
• W4282024761 creator A5034751834 @default.
• W4282024761 creator A5039161180 @default.
• W4282024761 creator A5039701125 @default.
• W4282024761 creator A5041736696 @default.
• W4282024761 creator A5042266153 @default.
• W4282024761 creator A5042764150 @default.
• W4282024761 creator A5043023229 @default.
• W4282024761 creator A5046399656 @default.
• W4282024761 creator A5049984747 @default.
• W4282024761 creator A5050327547 @default.
• W4282024761 creator A5050937741 @default.
• W4282024761 creator A5050999986 @default.
• W4282024761 creator A5053191551 @default.
• W4282024761 creator A5055362200 @default.
• W4282024761 creator A5059129773 @default.
• W4282024761 creator A5061353810 @default.
• W4282024761 creator A5061701955 @default.
• W4282024761 creator A5063955011 @default.
• W4282024761 creator A5066790760 @default.
• W4282024761 creator A5071375228 @default.
• W4282024761 creator A5074090192 @default.
• W4282024761 creator A5075059346 @default.
• W4282024761 creator A5075488395 @default.
• W4282024761 creator A5075589934 @default.
• W4282024761 creator A5076765290 @default.
• W4282024761 creator A5076877219 @default.
• W4282024761 creator A5077304867 @default.
• W4282024761 creator A5078629086 @default.
• W4282024761 creator A5084211419 @default.
• W4282024761 creator A5086450238 @default.
• W4282024761 creator A5088819771 @default.
• W4282024761 creator A5089664160 @default.
• W4282024761 date "2022-06-03" @default.
• W4282024761 modified "2023-10-15" @default.
• W4282024761 title "The role of sentinel node tumor burden in modeling the prognosis of melanoma patients with positive sentinel node biopsy: an Italian melanoma intergroup study (N = 2,086)" @default.
• W4282024761 cites W1982982185 @default.
• W4282024761 cites W2143422545 @default.
• W4282024761 cites W2346188454 @default.
• W4282024761 cites W2624147378 @default.
• W4282024761 cites W2736029224 @default.
• W4282024761 cites W2752210999 @default.
• W4282024761 cites W2752227448 @default.
• W4282024761 cites W2762347490 @default.
• W4282024761 cites W2765152685 @default.
• W4282024761 cites W2773801101 @default.
• W4282024761 cites W2796710340 @default.
• W4282024761 cites W2977026037 @default.
• W4282024761 cites W2977268874 @default.
• W4282024761 cites W2977532924 @default.
• W4282024761 cites W2984570826 @default.
• W4282024761 cites W3008716724 @default.
• W4282024761 cites W3027509246 @default.
• W4282024761 doi "https://doi.org/10.1186/s12885-022-09705-y" @default.
• W4282024761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35659273" @default.
• W4282024761 hasPublicationYear "2022" @default.
• W4282024761 type Work @default.
• W4282024761 citedByCount "4" @default.
• W4282024761 countsByYear W42820247612022 @default.
• W4282024761 countsByYear W42820247612023 @default.
• W4282024761 crossrefType "journal-article" @default.
• W4282024761 hasAuthorship W4282024761A5000391768 @default.
• W4282024761 hasAuthorship W4282024761A5001293319 @default.
• W4282024761 hasAuthorship W4282024761A5004401304 @default.
• W4282024761 hasAuthorship W4282024761A5005909861 @default.
• W4282024761 hasAuthorship W4282024761A5007431288 @default.
• W4282024761 hasAuthorship W4282024761A5008166009 @default.
• W4282024761 hasAuthorship W4282024761A5010533525 @default.
• W4282024761 hasAuthorship W4282024761A5010608336 @default.
• W4282024761 hasAuthorship W4282024761A5010831003 @default.
• W4282024761 hasAuthorship W4282024761A5011521807 @default.
• W4282024761 hasAuthorship W4282024761A5011613484 @default.
• W4282024761 hasAuthorship W4282024761A5018536695 @default.
• W4282024761 hasAuthorship W4282024761A5020324374 @default.
• W4282024761 hasAuthorship W4282024761A5023542650 @default.
• W4282024761 hasAuthorship W4282024761A5023633541 @default.

• next