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- W4282560034 abstract "BioFactorsVolume 48, Issue 3 p. 520-520 ISSUE HIGHLIGHTSFree Access Issue Highlights First published: 13 June 2022 https://doi.org/10.1002/biof.1743AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Curcuma longa and curcumin affect respiratory and allergic disorders, experimental and clinical evidence: A comprehensive and updated review Arghavan Memarzia, Saeideh Saadat, Sepideh Behrouz and Mohammad Hossein Boskabady The effects of Curcuma longa and curcumin on respiratory and allergic disorders: Curcuma longa is a traditional plant with wide range of pharmacological and theraputic effects. The relaxant effects of this plant and curcumin, on tracheal smooth muscle were shown indicating their bronchodilatory effect in obstructive pulmonary diseases. The preventive effects of Curcuma longa and curcumin were also shown in experimental and clinical studies on different respiratory diseases through antioxidant, immunomodulatory, anti-inflammatory, and varions signaling pathways mechanisms. Therefore the possible therapeutic effects of Curcuma longa and curcumin on respiratory, allergic, and immunologic disorders were indicated. 521 Nutrient-sensing amyloid metastasis Luís Maurício T. R. Lima and Tháyna Sisnande Amyloids are well-organized forms of polypeptides involved in several degenerative diseases. These polypeptides are converted from their non-pathogenic structures through varying mechanisms, which can be directly and/or indirectly regulated by essential micronutrients, in particular transition metals. Amyloids can be metastatic, and also serve as a template for the assembly of other amyloid proteins, resulting in multiple amyloidosis. Along with the regulation by metals, amyloidosis can be seen as nutrient sensors driving the physiology and pathophysiology of biological processes. 552 Recent research progress of biologically active peptides Linlin Kang, Tingting Han, Hailin Cong, Bing Yu and Youqing Shen With the rapid development of molecular biology and biochemical technology, great progress has been made in the study of peptides. Peptides are easy to digest and absorb, with lowering of blood pressure and cholesterol, improving immunity, regulating hormones, antibacterial, and antiviral effects. Peptides also have physiological regulation and biological metabolism functions with applications in the fields of feed production and biomedical research. In the future, the research focus of bioactive peptides will focus on their efficient preparation and application. This article introduces a comprehensive review of the types, synthesis, functionalization, and bio-related applications of bioactive peptides. For this aim, we introduced in detail various biopeptides and then presented the production methods of bioactive peptides, such as enzymatic synthesis, microbial fermentation, chemical synthesis, and others. The applications of bioactive peptides for anticancers, immune therapy, antibacterial, and other applications have been introduced and discussed. 575 The cardioprotective effects of nano-curcumin against doxorubicin-induced cardiotoxicity: A systematic review Hossein Moutabian, Ruhollah Ghahramani-Asl, Tohid Mortezazadeh, Reza Laripour, Asghar Narmani, Hamed Zamani, Gholamreza Ataei, Hamed Bagheri, Bagher Farhood, Thozhukat Sathyapalan and Amirhossein Sahebkar Although the chemotherapeutic drug, doxorubicin, is commonly used to treat various malignant tumors, its clinical use is restricted because of its toxicity especially cardiotoxicity. In this study, the authors systematically reviewed the potential cardioprotective effects of nano-curcumin against the doxorubicin-induced cardiotoxicity. Coadministration of nano-curcumin with doxorubicin decreased the effects on heart weight and alleviated the doxorubicin-induced biochemical and histopathological changes. Additionally, their review shows that the cardioprotective effect of nano-curcumin formulation against doxorubicin-induced cardiotoxicity was higher than free curcumin. 597 The role of plant-derived natural antioxidants in reduction of oxidative stress Behnaz Akbari, Namdar Baghaei-Yazdi, Manochehr Bahmaie and Fatemeh Mahdavi Abhari Free radicals are a group of damaging molecules produced during the normal metabolism of cells in the human body as well after exposure to ultraviolet radiation, cigarette smoking, and other environmental pollutants. The destructive effects of free radicals may also cause harm to membranes, enzymes, and DNA, leading to several human diseases such as cancer, atherosclerosis, malaria, coronavirus disease (COVID-19), rheumatoid arthritis, and neurodegenerative illnesses. In this review article, Akbari et al explore the role of natural therapeutic antioxidant effects to reduce oxidative stress in the diseases. 611 REFERENCES 1Arghavan Memarzia, Saeideh Saadat, Sepideh Behrouz and Mohammad Hossein Boskabady. Curcuma longa and curcumin affect respiratory and allergic disorders, experimental and clinical evidence: A comprehensive and updated review. BioFactors. 2022; 48: 521– 551. Wiley Online LibraryGoogle Scholar 2Luís Maurício T. R. Lima and Tháyna Sisnande. Nutrient-sensing amyloid metastasis. BioFactors. 2022; 48: 552– 574. Wiley Online LibraryGoogle Scholar 3Linlin Kang, Tingting Han, Hailin Cong, Bing Yu and Youqing Shen. Recent research progress of biologically active peptides. BioFactors. 2022; 48: 575– 596. Wiley Online LibraryGoogle Scholar 4Hossein Moutabian, Ruhollah Ghahramani-Asl, Tohid Mortezazadeh, Reza Laripour, Asghar Narmani, Hamed Zamani, Gholamreza Ataei, Hamed Bagheri, Bagher Farhood, Thozhukat Sathyapalan and Amirhossein Sahebkar. The cardioprotective effects of nano-curcumin against doxorubicin-induced cardiotoxicity: A systematic review. BioFactors. 2022; 48: 597– 610. Wiley Online LibraryGoogle Scholar 5Behnaz Akbari, Namdar Baghaei-Yazdi, Manochehr Bahmaie and Fatemeh Mahdavi Abhari. The role of plant-derived natural antioxidants in reduction of oxidative stress. BioFactors. 2022; 48: 611– 633. Wiley Online LibraryGoogle Scholar Volume48, Issue3May/June 2022Pages 520-520 ReferencesRelatedInformation" @default.
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