Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282592326> ?p ?o ?g. }
- W4282592326 abstract "Autotaxin (ATX) is a secreted glycoprotein and catalyzes the hydrolysis of lysophosphatidylcholine to lysophosphatidic acid (LPA), a growth factor-like signaling phospholipid. ATX has been abundantly detected in the culture medium of various cancer cells, tumor tissues, and serum or plasma of cancer patients. Biological actions of ATX are mediated by LPA. The ATX-LPA axis mediates a plethora of activities, such as cell proliferation, survival, migration, angiogenesis, and inflammation, and participates in the regulation of various physiological and pathological processes. In this review, we have summarized the physiological function of ATX and the ATX-LPA axis in liver cancer, analyzed the role of the ATX-LPA axis in tumorigenesis and metastasis, and discussed the therapeutic strategies targeting the ATX-LPA axis, paving the way for new therapeutic developments." @default.
- W4282592326 created "2022-06-14" @default.
- W4282592326 creator A5018748194 @default.
- W4282592326 creator A5021112277 @default.
- W4282592326 creator A5033800024 @default.
- W4282592326 creator A5052441498 @default.
- W4282592326 creator A5085069755 @default.
- W4282592326 date "2022-06-13" @default.
- W4282592326 modified "2023-10-01" @default.
- W4282592326 title "Roles of Autotaxin/Autotaxin-Lysophosphatidic Acid Axis in the Initiation and Progression of Liver Cancer" @default.
- W4282592326 cites W1526385063 @default.
- W4282592326 cites W1577193899 @default.
- W4282592326 cites W1973398707 @default.
- W4282592326 cites W1984780427 @default.
- W4282592326 cites W1989787117 @default.
- W4282592326 cites W1990390822 @default.
- W4282592326 cites W1999599951 @default.
- W4282592326 cites W2003992176 @default.
- W4282592326 cites W2006993784 @default.
- W4282592326 cites W2036471410 @default.
- W4282592326 cites W2041516349 @default.
- W4282592326 cites W2075738256 @default.
- W4282592326 cites W2089737950 @default.
- W4282592326 cites W2098615703 @default.
- W4282592326 cites W2114581301 @default.
- W4282592326 cites W2139687720 @default.
- W4282592326 cites W2145095296 @default.
- W4282592326 cites W2153704241 @default.
- W4282592326 cites W2163945848 @default.
- W4282592326 cites W2171878662 @default.
- W4282592326 cites W2202874374 @default.
- W4282592326 cites W2263484855 @default.
- W4282592326 cites W2277723007 @default.
- W4282592326 cites W2508784426 @default.
- W4282592326 cites W2566736848 @default.
- W4282592326 cites W2581172641 @default.
- W4282592326 cites W2597890536 @default.
- W4282592326 cites W2621344251 @default.
- W4282592326 cites W2623741450 @default.
- W4282592326 cites W2739717330 @default.
- W4282592326 cites W2792376809 @default.
- W4282592326 cites W2802846700 @default.
- W4282592326 cites W2891366292 @default.
- W4282592326 cites W2912997222 @default.
- W4282592326 cites W2920517824 @default.
- W4282592326 cites W2973405239 @default.
- W4282592326 cites W2976358175 @default.
- W4282592326 cites W2981707092 @default.
- W4282592326 cites W2995910775 @default.
- W4282592326 cites W2998012556 @default.
- W4282592326 cites W2998257435 @default.
- W4282592326 cites W2999483628 @default.
- W4282592326 cites W3017007571 @default.
- W4282592326 cites W3023655080 @default.
- W4282592326 cites W3024712300 @default.
- W4282592326 cites W3113976889 @default.
- W4282592326 cites W3123447987 @default.
- W4282592326 cites W3148503778 @default.
- W4282592326 cites W3153945694 @default.
- W4282592326 cites W3169670964 @default.
- W4282592326 cites W3173240739 @default.
- W4282592326 doi "https://doi.org/10.3389/fonc.2022.922945" @default.
- W4282592326 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35769713" @default.
- W4282592326 hasPublicationYear "2022" @default.
- W4282592326 type Work @default.
- W4282592326 citedByCount "5" @default.
- W4282592326 countsByYear W42825923262022 @default.
- W4282592326 countsByYear W42825923262023 @default.
- W4282592326 crossrefType "journal-article" @default.
- W4282592326 hasAuthorship W4282592326A5018748194 @default.
- W4282592326 hasAuthorship W4282592326A5021112277 @default.
- W4282592326 hasAuthorship W4282592326A5033800024 @default.
- W4282592326 hasAuthorship W4282592326A5052441498 @default.
- W4282592326 hasAuthorship W4282592326A5085069755 @default.
- W4282592326 hasBestOaLocation W42825923261 @default.
- W4282592326 hasConcept C121608353 @default.
- W4282592326 hasConcept C126322002 @default.
- W4282592326 hasConcept C170493617 @default.
- W4282592326 hasConcept C185592680 @default.
- W4282592326 hasConcept C2776330855 @default.
- W4282592326 hasConcept C2776661833 @default.
- W4282592326 hasConcept C2778596009 @default.
- W4282592326 hasConcept C2778918659 @default.
- W4282592326 hasConcept C2779013556 @default.
- W4282592326 hasConcept C2780394083 @default.
- W4282592326 hasConcept C37547375 @default.
- W4282592326 hasConcept C41625074 @default.
- W4282592326 hasConcept C502942594 @default.
- W4282592326 hasConcept C55493867 @default.
- W4282592326 hasConcept C555283112 @default.
- W4282592326 hasConcept C62112901 @default.
- W4282592326 hasConcept C71924100 @default.
- W4282592326 hasConcept C86803240 @default.
- W4282592326 hasConcept C95444343 @default.
- W4282592326 hasConcept C96232424 @default.
- W4282592326 hasConceptScore W4282592326C121608353 @default.
- W4282592326 hasConceptScore W4282592326C126322002 @default.
- W4282592326 hasConceptScore W4282592326C170493617 @default.
- W4282592326 hasConceptScore W4282592326C185592680 @default.
- W4282592326 hasConceptScore W4282592326C2776330855 @default.