Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282823611> ?p ?o ?g. }
- W4282823611 endingPage "6597" @default.
- W4282823611 startingPage "6597" @default.
- W4282823611 abstract "The clinical use of anticancer drugs necessitates new technologies for their safe, sensitive, and selective detection. In this article, lanthanide (Eu3+ and Tb3+)-loaded γ-cyclodextrin nano-aggregates (ECA and TCA) are reported, which sensitively detects the anticancer drug irinotecan by fluorescence intensity changes. Fluorescent lanthanide (Eu3+ and Tb3+) complexes exhibit high fluorescence intensity, narrow and distinct emission bands, long fluorescence lifetime, and insensitivity to photobleaching. However, these lanthanide (Eu3+ and Tb3+) complexes are essentially hydrophobic, toxic, and non-biocompatible. Lanthanide (Eu3+ and Tb3+) complexes were loaded into naturally hydrophilic γ-cyclodextrin to form fluorescent nano-aggregates. The biological nontoxicity and cytocompatibility of ECA and TCA fluorescent nanoparticles were demonstrated by cytotoxicity experiments. The ECA and TCA fluorescence nanosensors can detect irinotecan selectively and sensitively through the change of fluorescence intensity, with detection limits of 6.80 μM and 2.89 μM, respectively. ECA can safely detect irinotecan in the cellular environment, while TCA can detect irinotecan intracellularly and is suitable for cell labeling." @default.
- W4282823611 created "2022-06-15" @default.
- W4282823611 creator A5000970532 @default.
- W4282823611 creator A5003592984 @default.
- W4282823611 creator A5005412372 @default.
- W4282823611 creator A5006250732 @default.
- W4282823611 creator A5014288383 @default.
- W4282823611 creator A5018035456 @default.
- W4282823611 creator A5048373292 @default.
- W4282823611 creator A5051556141 @default.
- W4282823611 creator A5052336253 @default.
- W4282823611 creator A5053817652 @default.
- W4282823611 creator A5062535804 @default.
- W4282823611 creator A5083417541 @default.
- W4282823611 date "2022-06-13" @default.
- W4282823611 modified "2023-10-01" @default.
- W4282823611 title "Lanthanide (Eu3+/Tb3+)-Loaded γ-Cyclodextrin Nano-Aggregates for Smart Sensing of the Anticancer Drug Irinotecan" @default.
- W4282823611 cites W1937111512 @default.
- W4282823611 cites W1977356115 @default.
- W4282823611 cites W1989863074 @default.
- W4282823611 cites W2002698112 @default.
- W4282823611 cites W2023000498 @default.
- W4282823611 cites W2031281559 @default.
- W4282823611 cites W2092185865 @default.
- W4282823611 cites W2106654936 @default.
- W4282823611 cites W2329655773 @default.
- W4282823611 cites W2540793423 @default.
- W4282823611 cites W2626848319 @default.
- W4282823611 cites W2762828059 @default.
- W4282823611 cites W2790768119 @default.
- W4282823611 cites W2793313898 @default.
- W4282823611 cites W2800282559 @default.
- W4282823611 cites W2892295138 @default.
- W4282823611 cites W2900703360 @default.
- W4282823611 cites W2907543200 @default.
- W4282823611 cites W2907712810 @default.
- W4282823611 cites W2921138253 @default.
- W4282823611 cites W2927113896 @default.
- W4282823611 cites W2977731220 @default.
- W4282823611 cites W2999814743 @default.
- W4282823611 cites W3003713260 @default.
- W4282823611 cites W3012547663 @default.
- W4282823611 cites W3016421959 @default.
- W4282823611 cites W3022916699 @default.
- W4282823611 cites W3022997134 @default.
- W4282823611 cites W3027409689 @default.
- W4282823611 cites W3030741490 @default.
- W4282823611 cites W3038821555 @default.
- W4282823611 cites W3045350693 @default.
- W4282823611 cites W3046917027 @default.
- W4282823611 cites W3049268670 @default.
- W4282823611 cites W3073861431 @default.
- W4282823611 cites W3076904174 @default.
- W4282823611 cites W3093420059 @default.
- W4282823611 cites W3118277349 @default.
- W4282823611 cites W3119166671 @default.
- W4282823611 cites W3120466474 @default.
- W4282823611 cites W3126240628 @default.
- W4282823611 cites W3127032071 @default.
- W4282823611 cites W3133767838 @default.
- W4282823611 cites W3134007716 @default.
- W4282823611 cites W3135535885 @default.
- W4282823611 cites W3136452922 @default.
- W4282823611 cites W3140405789 @default.
- W4282823611 cites W3163839024 @default.
- W4282823611 cites W3169308470 @default.
- W4282823611 cites W3170497773 @default.
- W4282823611 cites W3182056976 @default.
- W4282823611 cites W3185754477 @default.
- W4282823611 cites W3194308284 @default.
- W4282823611 cites W3194876833 @default.
- W4282823611 doi "https://doi.org/10.3390/ijms23126597" @default.
- W4282823611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35743042" @default.
- W4282823611 hasPublicationYear "2022" @default.
- W4282823611 type Work @default.
- W4282823611 citedByCount "4" @default.
- W4282823611 countsByYear W42828236112022 @default.
- W4282823611 countsByYear W42828236112023 @default.
- W4282823611 crossrefType "journal-article" @default.
- W4282823611 hasAuthorship W4282823611A5000970532 @default.
- W4282823611 hasAuthorship W4282823611A5003592984 @default.
- W4282823611 hasAuthorship W4282823611A5005412372 @default.
- W4282823611 hasAuthorship W4282823611A5006250732 @default.
- W4282823611 hasAuthorship W4282823611A5014288383 @default.
- W4282823611 hasAuthorship W4282823611A5018035456 @default.
- W4282823611 hasAuthorship W4282823611A5048373292 @default.
- W4282823611 hasAuthorship W4282823611A5051556141 @default.
- W4282823611 hasAuthorship W4282823611A5052336253 @default.
- W4282823611 hasAuthorship W4282823611A5053817652 @default.
- W4282823611 hasAuthorship W4282823611A5062535804 @default.
- W4282823611 hasAuthorship W4282823611A5083417541 @default.
- W4282823611 hasBestOaLocation W42828236111 @default.
- W4282823611 hasConcept C121332964 @default.
- W4282823611 hasConcept C121608353 @default.
- W4282823611 hasConcept C12554922 @default.
- W4282823611 hasConcept C126322002 @default.
- W4282823611 hasConcept C13965031 @default.
- W4282823611 hasConcept C145148216 @default.