Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282824965> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4282824965 endingPage "47" @default.
- W4282824965 startingPage "36" @default.
- W4282824965 abstract "Aim: Infertility is a global problem affecting both males and females. It is a condition with psychological, economic, and medical implications resulting in trauma and stress, particularly in a society where there is a strong emphasis on childbearing. The study therefore aims to investigate the pattern of some sperm proteins, anti-oxidants, and prostate-specific antigen in the seminal plasma of infertile males with sperm cell deformities.
 Study Design: The study is a case-control study designed to investigate semen parameters and sperm proteins in infertile males with sperm cell deformities in Port Harcourt, Rivers State.
 Place and Duration of Study: The study was carried out in the Department of Medical Laboratory Science, Rivers State University, Port Harcourt. However, some of the Laboratory investigations were done in the Chemical Pathology Unit and Medical Microbiology Unit of the University of Port Harcourt Teaching Hospital, Port Harcourt. The Study was between the periods of September 2019 and Feb. 2022.
 Methodology: A total of 276 males indicated interest to participate in the study of which 193 male subjects were recruited. These subjects were grouped into normospermic males (100), azoospermic (40) and oligospermic males (53). Based on their sperm cell morphology and active motility, they were further classified into asthenozoospermic (40), oligoasthenozoospermic (48), teratozoospermic (26), asthenoteratozoospermic (32), and oligoasthenoteratozoospermic (22). HSP70, PKA, MDA, TAC, and GPX (in seminal plasma), PSA, and testosterone (in serum) were analyzed using ELISA while TAC was done using spectrophotometric methods. Results obtained were statistically analyzed using GraphPad Prism and SPSS.
 Results: Sperm motility, TSC, and normal sperm morphology were poor in oligospermic subjects but were very severe in OAT subjects. Sperm proteins were altered in subjects with abnormal sperm cell morphologies. HSP70 and PKA were significantly increased while OPN, TAC, and GPX were significantly decreased in the seminal plasma of infertile males with abnormal sperm cells. Testosterone and PSA in blood plasma were significantly lower and higher respectively.
 Conclusion: Oxidative stress played a significant role in sperm cell deformities and fertility. OAT subjects were the most affected." @default.
- W4282824965 created "2022-06-15" @default.
- W4282824965 creator A5033467639 @default.
- W4282824965 creator A5040724602 @default.
- W4282824965 creator A5053250902 @default.
- W4282824965 creator A5065527431 @default.
- W4282824965 creator A5068312058 @default.
- W4282824965 date "2022-06-11" @default.
- W4282824965 modified "2023-10-14" @default.
- W4282824965 title "Pattern of Some Sperm Proteins, Anti-oxidants, Testosterone, and Prostate-Specific Antigen of Infertile Males with Sperm Cell Deformities in Port Harcourt, Rivers State" @default.
- W4282824965 doi "https://doi.org/10.9734/ajrimps/2022/v11i230186" @default.
- W4282824965 hasPublicationYear "2022" @default.
- W4282824965 type Work @default.
- W4282824965 citedByCount "1" @default.
- W4282824965 countsByYear W42828249652023 @default.
- W4282824965 crossrefType "journal-article" @default.
- W4282824965 hasAuthorship W4282824965A5033467639 @default.
- W4282824965 hasAuthorship W4282824965A5040724602 @default.
- W4282824965 hasAuthorship W4282824965A5053250902 @default.
- W4282824965 hasAuthorship W4282824965A5065527431 @default.
- W4282824965 hasAuthorship W4282824965A5068312058 @default.
- W4282824965 hasBestOaLocation W42828249651 @default.
- W4282824965 hasConcept C126322002 @default.
- W4282824965 hasConcept C144024400 @default.
- W4282824965 hasConcept C16685009 @default.
- W4282824965 hasConcept C2777338322 @default.
- W4282824965 hasConcept C2777632594 @default.
- W4282824965 hasConcept C2777688143 @default.
- W4282824965 hasConcept C2778054964 @default.
- W4282824965 hasConcept C2778093475 @default.
- W4282824965 hasConcept C2779234561 @default.
- W4282824965 hasConcept C2779279991 @default.
- W4282824965 hasConcept C2781087480 @default.
- W4282824965 hasConcept C29456083 @default.
- W4282824965 hasConcept C3018293340 @default.
- W4282824965 hasConcept C42407357 @default.
- W4282824965 hasConcept C45355965 @default.
- W4282824965 hasConcept C54355233 @default.
- W4282824965 hasConcept C71924100 @default.
- W4282824965 hasConcept C86803240 @default.
- W4282824965 hasConceptScore W4282824965C126322002 @default.
- W4282824965 hasConceptScore W4282824965C144024400 @default.
- W4282824965 hasConceptScore W4282824965C16685009 @default.
- W4282824965 hasConceptScore W4282824965C2777338322 @default.
- W4282824965 hasConceptScore W4282824965C2777632594 @default.
- W4282824965 hasConceptScore W4282824965C2777688143 @default.
- W4282824965 hasConceptScore W4282824965C2778054964 @default.
- W4282824965 hasConceptScore W4282824965C2778093475 @default.
- W4282824965 hasConceptScore W4282824965C2779234561 @default.
- W4282824965 hasConceptScore W4282824965C2779279991 @default.
- W4282824965 hasConceptScore W4282824965C2781087480 @default.
- W4282824965 hasConceptScore W4282824965C29456083 @default.
- W4282824965 hasConceptScore W4282824965C3018293340 @default.
- W4282824965 hasConceptScore W4282824965C42407357 @default.
- W4282824965 hasConceptScore W4282824965C45355965 @default.
- W4282824965 hasConceptScore W4282824965C54355233 @default.
- W4282824965 hasConceptScore W4282824965C71924100 @default.
- W4282824965 hasConceptScore W4282824965C86803240 @default.
- W4282824965 hasLocation W42828249651 @default.
- W4282824965 hasOpenAccess W4282824965 @default.
- W4282824965 hasPrimaryLocation W42828249651 @default.
- W4282824965 hasRelatedWork W1910139643 @default.
- W4282824965 hasRelatedWork W1973007694 @default.
- W4282824965 hasRelatedWork W2023358601 @default.
- W4282824965 hasRelatedWork W2085443960 @default.
- W4282824965 hasRelatedWork W2101853143 @default.
- W4282824965 hasRelatedWork W2356784823 @default.
- W4282824965 hasRelatedWork W2377560903 @default.
- W4282824965 hasRelatedWork W2382159885 @default.
- W4282824965 hasRelatedWork W2413976810 @default.
- W4282824965 hasRelatedWork W2596204441 @default.
- W4282824965 isParatext "false" @default.
- W4282824965 isRetracted "false" @default.
- W4282824965 workType "article" @default.