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- W4282831736 abstract "Background: The impact of BMI on immune checkpoint inhibitor toxicity and efficacy has not been clearly characterized. Methods: The authors conducted a retrospective single-center study of patients with advanced unresectable/metastatic cancer initiated on immune checkpoint inhibitors. Results: Of the 409 patients included in the study, 115 (28%) had a BMI ≥30. There was no difference in the development of immune-related adverse events, treatment response or overall survival with respect to BMI <30 versus ≥30 for the whole study population or the melanoma subgroup. Conclusion: Patients with BMI in the obese range (≥30) were not at increased risk of immunotoxicity. Furthermore, BMI was not correlated with treatment response or overall survival in patients receiving immune checkpoint inhibitors." @default.
- W4282831736 created "2022-06-15" @default.
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- W4282831736 date "2022-07-01" @default.
- W4282831736 modified "2023-09-24" @default.
- W4282831736 title "No association between BMI and immunotoxicity or clinical outcomes for immune checkpoint inhibitors" @default.
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- W4282831736 doi "https://doi.org/10.2217/imt-2021-0250" @default.
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