Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282916712> ?p ?o ?g. }
- W4282916712 endingPage "119" @default.
- W4282916712 startingPage "106" @default.
- W4282916712 abstract "The effect of UV/visible/NIR light (380/450/530/650/808/1064 nm) on ROS generation, mitochondrial activity and viability is experimentally compared in human neuroblastoma cancer cells. The absorption of photons by mitochondrial photoacceptors in Complexes I, III and IV is in detail investigated by sequential blocking with selective pharmaceutical blockers. Complex I absorbs UV/blue light by heme P450, resulting in a very high rate (14 times) of ROS generation leading to cell death. Complex III absorbs green light, by cytochromes b, c1 and c, and possesses less ability for ROS production (seven times), so that only irradiation lower than 10 mW cm-2 causes an increase in cell viability. Complex IV is well-known as the primary photoacceptor for red/NIR light. Light of 650/808 nm at 10-100 mW cm-2 generates a physiological ROS level about 20% of a basal concentration, which enhance mitochondrial activity and cell survival, while 1064 nm light does not show any distinguished effects. Further, ROS generation induced by low-intensity red/NIR light is compared in neurons, immune and cancer cells. Red light seems to more rapidly stimulate ROS production, mitochondrial activity and cell survival than 808 nm. At the same time, different cell lines demonstrate slightly various rates of ROS generation, peculiar to their cellular physiology." @default.
- W4282916712 created "2022-06-16" @default.
- W4282916712 creator A5060335913 @default.
- W4282916712 creator A5089250135 @default.
- W4282916712 date "2022-07-04" @default.
- W4282916712 modified "2023-10-16" @default.
- W4282916712 title "Comparing the Impact of <scp>NIR</scp>, Visible and <scp>UV</scp> Light on <scp>ROS</scp> Upregulation <i>via</i> Photoacceptors of Mitochondrial Complexes in Normal, Immune and Cancer Cells" @default.
- W4282916712 cites W1522211358 @default.
- W4282916712 cites W1523213544 @default.
- W4282916712 cites W1607721485 @default.
- W4282916712 cites W1615043918 @default.
- W4282916712 cites W1760733126 @default.
- W4282916712 cites W1909888178 @default.
- W4282916712 cites W1965637904 @default.
- W4282916712 cites W1966763936 @default.
- W4282916712 cites W1973624424 @default.
- W4282916712 cites W1975593366 @default.
- W4282916712 cites W1983737836 @default.
- W4282916712 cites W1984601360 @default.
- W4282916712 cites W1987127397 @default.
- W4282916712 cites W2006555923 @default.
- W4282916712 cites W2016468663 @default.
- W4282916712 cites W2016693012 @default.
- W4282916712 cites W2023832396 @default.
- W4282916712 cites W2027591857 @default.
- W4282916712 cites W2029119853 @default.
- W4282916712 cites W2037607943 @default.
- W4282916712 cites W2039751653 @default.
- W4282916712 cites W2042208647 @default.
- W4282916712 cites W2044414180 @default.
- W4282916712 cites W2050897300 @default.
- W4282916712 cites W2053829558 @default.
- W4282916712 cites W2054748571 @default.
- W4282916712 cites W2056015556 @default.
- W4282916712 cites W2060158326 @default.
- W4282916712 cites W2061475164 @default.
- W4282916712 cites W2064443786 @default.
- W4282916712 cites W2064553763 @default.
- W4282916712 cites W2070712953 @default.
- W4282916712 cites W2073691597 @default.
- W4282916712 cites W2077722456 @default.
- W4282916712 cites W2082736102 @default.
- W4282916712 cites W2084299658 @default.
- W4282916712 cites W2093724972 @default.
- W4282916712 cites W2101061670 @default.
- W4282916712 cites W2109916620 @default.
- W4282916712 cites W2110597788 @default.
- W4282916712 cites W2110900455 @default.
- W4282916712 cites W2112438801 @default.
- W4282916712 cites W2128038980 @default.
- W4282916712 cites W2135659582 @default.
- W4282916712 cites W2143986750 @default.
- W4282916712 cites W2146337290 @default.
- W4282916712 cites W2150909904 @default.
- W4282916712 cites W2153287706 @default.
- W4282916712 cites W2162638931 @default.
- W4282916712 cites W2164944202 @default.
- W4282916712 cites W2171601635 @default.
- W4282916712 cites W2191230296 @default.
- W4282916712 cites W2253787186 @default.
- W4282916712 cites W2285656511 @default.
- W4282916712 cites W2312323807 @default.
- W4282916712 cites W2336416528 @default.
- W4282916712 cites W2340832220 @default.
- W4282916712 cites W2401439428 @default.
- W4282916712 cites W2414212658 @default.
- W4282916712 cites W2489617453 @default.
- W4282916712 cites W2503486429 @default.
- W4282916712 cites W2529932117 @default.
- W4282916712 cites W2561516959 @default.
- W4282916712 cites W2587742119 @default.
- W4282916712 cites W2606455540 @default.
- W4282916712 cites W2607303579 @default.
- W4282916712 cites W2611798400 @default.
- W4282916712 cites W2615482484 @default.
- W4282916712 cites W2744285886 @default.
- W4282916712 cites W2753431956 @default.
- W4282916712 cites W2767702835 @default.
- W4282916712 cites W2793481007 @default.
- W4282916712 cites W2799875138 @default.
- W4282916712 cites W2801692664 @default.
- W4282916712 cites W2887981390 @default.
- W4282916712 cites W2888507952 @default.
- W4282916712 cites W2889459691 @default.
- W4282916712 cites W2913342269 @default.
- W4282916712 cites W2914829743 @default.
- W4282916712 cites W2943809698 @default.
- W4282916712 cites W2954571334 @default.
- W4282916712 cites W2961894100 @default.
- W4282916712 cites W2996739107 @default.
- W4282916712 cites W3044475390 @default.
- W4282916712 cites W3044830556 @default.
- W4282916712 cites W3083005546 @default.
- W4282916712 cites W3106836330 @default.
- W4282916712 cites W3135192817 @default.
- W4282916712 cites W3202016535 @default.
- W4282916712 cites W4206254303 @default.
- W4282916712 doi "https://doi.org/10.1111/php.13661" @default.