Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282916808> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4282916808 endingPage "755" @default.
- W4282916808 startingPage "749" @default.
- W4282916808 abstract "Ductal epithelial changes (lympho-epithelial lesions-LEL) in prostatic chronic inflammation (CI) are not well studied so far.to investigate LEL immediately adjacent to prostatic CI.We studied LEL in 144 prostatic surgical and autopsy specimens in various types of prostatic CI: NIH-category IV prostatitis (histologic prostatitis-HP), nonspecific granulomatous prostatitis (NSGP), and the reactive lymphoid infiltrates in the vicinity of benign prostatic hyperplasia (BPH) and prostate adenocarcinoma (PCa). CI is scored as low and high grade (LG, HG) according to the severity of inflammation.LEL was identified in all types of prostatic specimens and in all types of prostatic CI: in 70.9% of patients with HP; in 100% of cases with NSGP; in 68.7% and in 80% adjacent to BPH and PCa respectively. Statistical analysis showed a significant correlation of the presence of LEL with HG CI (p<0.001). LEL showed strong membranous PD-L1 expression.The study presents the first attempt to examine LEL in inflammatory human prostate. PD-L1 positive LEL have no diagnostic organ specificity, although they are a constant histological finding in HG prostatic CI. LEL, inducible after birth by CI, are an integral part of prostate-associated lymphoid tissue (PALT) and of the inflammatory prostatic microenvironment." @default.
- W4282916808 created "2022-06-16" @default.
- W4282916808 creator A5007221303 @default.
- W4282916808 creator A5048708472 @default.
- W4282916808 creator A5050676137 @default.
- W4282916808 creator A5057911300 @default.
- W4282916808 creator A5075375825 @default.
- W4282916808 date "2022-08-01" @default.
- W4282916808 modified "2023-09-26" @default.
- W4282916808 title "PD-L1 positive lympho-epithelial lesions in inflammatory prostate." @default.
- W4282916808 cites W1508723053 @default.
- W4282916808 cites W1608440954 @default.
- W4282916808 cites W1975400470 @default.
- W4282916808 cites W2019330552 @default.
- W4282916808 cites W2027326367 @default.
- W4282916808 cites W2057159794 @default.
- W4282916808 cites W2059724367 @default.
- W4282916808 cites W2077060929 @default.
- W4282916808 cites W2082060059 @default.
- W4282916808 cites W2111455561 @default.
- W4282916808 cites W2115917808 @default.
- W4282916808 cites W2118383779 @default.
- W4282916808 cites W2155464214 @default.
- W4282916808 cites W2164205997 @default.
- W4282916808 cites W2334096923 @default.
- W4282916808 cites W2344610509 @default.
- W4282916808 cites W2765533007 @default.
- W4282916808 cites W2909306803 @default.
- W4282916808 cites W2996536924 @default.
- W4282916808 cites W3007203022 @default.
- W4282916808 cites W3110296131 @default.
- W4282916808 doi "https://doi.org/10.14670/hh-18-479" @default.
- W4282916808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35670049" @default.
- W4282916808 hasPublicationYear "2022" @default.
- W4282916808 type Work @default.
- W4282916808 citedByCount "0" @default.
- W4282916808 crossrefType "journal-article" @default.
- W4282916808 hasAuthorship W4282916808A5007221303 @default.
- W4282916808 hasAuthorship W4282916808A5048708472 @default.
- W4282916808 hasAuthorship W4282916808A5050676137 @default.
- W4282916808 hasAuthorship W4282916808A5057911300 @default.
- W4282916808 hasAuthorship W4282916808A5075375825 @default.
- W4282916808 hasConcept C121608353 @default.
- W4282916808 hasConcept C126322002 @default.
- W4282916808 hasConcept C126894567 @default.
- W4282916808 hasConcept C142724271 @default.
- W4282916808 hasConcept C2776235491 @default.
- W4282916808 hasConcept C2776914184 @default.
- W4282916808 hasConcept C2777562237 @default.
- W4282916808 hasConcept C2780524745 @default.
- W4282916808 hasConcept C2911124710 @default.
- W4282916808 hasConcept C71924100 @default.
- W4282916808 hasConceptScore W4282916808C121608353 @default.
- W4282916808 hasConceptScore W4282916808C126322002 @default.
- W4282916808 hasConceptScore W4282916808C126894567 @default.
- W4282916808 hasConceptScore W4282916808C142724271 @default.
- W4282916808 hasConceptScore W4282916808C2776235491 @default.
- W4282916808 hasConceptScore W4282916808C2776914184 @default.
- W4282916808 hasConceptScore W4282916808C2777562237 @default.
- W4282916808 hasConceptScore W4282916808C2780524745 @default.
- W4282916808 hasConceptScore W4282916808C2911124710 @default.
- W4282916808 hasConceptScore W4282916808C71924100 @default.
- W4282916808 hasIssue "8" @default.
- W4282916808 hasLocation W42829168081 @default.
- W4282916808 hasOpenAccess W4282916808 @default.
- W4282916808 hasPrimaryLocation W42829168081 @default.
- W4282916808 hasRelatedWork W1731047237 @default.
- W4282916808 hasRelatedWork W1865537960 @default.
- W4282916808 hasRelatedWork W2014859164 @default.
- W4282916808 hasRelatedWork W2092964001 @default.
- W4282916808 hasRelatedWork W2103241343 @default.
- W4282916808 hasRelatedWork W2125390736 @default.
- W4282916808 hasRelatedWork W2349263218 @default.
- W4282916808 hasRelatedWork W2351525166 @default.
- W4282916808 hasRelatedWork W2400755480 @default.
- W4282916808 hasRelatedWork W2964635080 @default.
- W4282916808 hasVolume "37" @default.
- W4282916808 isParatext "false" @default.
- W4282916808 isRetracted "false" @default.
- W4282916808 workType "article" @default.