Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282920900> ?p ?o ?g. }
- W4282920900 endingPage "373" @default.
- W4282920900 startingPage "373" @default.
- W4282920900 abstract "In the past, there was no second-line chemotherapeutic agent suitable for use when urothelial carcinoma (UC) progressed to platinum-resistant UC. However, recently, several new treatment options, such as immune checkpoint inhibitors or targeted therapy have shifted the treatment paradigm regarding second-line therapeutic modalities. A novel class of therapeutic agents includes an antibody-drug conjugate (ADC). ADCs consist of three characteristics: a monoclonal antibody, linker, and payload. The specificity of the monoclonal antibody facilitates the delivery of a linked cytotoxic drug directly into the target tumor cell. Although various ADCs have been developed and approved for use in treating several solid tumors, almost all ADCs for the treatment of UC are still in the testing phase. Here, we review the key points about ADCs and summarize the novel ADCs that are approved or are involved in ongoing studies in UC." @default.
- W4282920900 created "2022-06-16" @default.
- W4282920900 creator A5013052304 @default.
- W4282920900 creator A5023550307 @default.
- W4282920900 date "2022-01-01" @default.
- W4282920900 modified "2023-10-14" @default.
- W4282920900 title "A novel strategy for treatment of bladder cancer: Antibody-drug conjugates" @default.
- W4282920900 cites W1692977678 @default.
- W4282920900 cites W1893740135 @default.
- W4282920900 cites W1959902744 @default.
- W4282920900 cites W1965278354 @default.
- W4282920900 cites W1974722941 @default.
- W4282920900 cites W1990918503 @default.
- W4282920900 cites W2007084442 @default.
- W4282920900 cites W2011157682 @default.
- W4282920900 cites W2013194808 @default.
- W4282920900 cites W2022414372 @default.
- W4282920900 cites W2025338891 @default.
- W4282920900 cites W2030611514 @default.
- W4282920900 cites W2041142448 @default.
- W4282920900 cites W2056405796 @default.
- W4282920900 cites W2065855960 @default.
- W4282920900 cites W2067011387 @default.
- W4282920900 cites W2068523052 @default.
- W4282920900 cites W2097450554 @default.
- W4282920900 cites W2099560139 @default.
- W4282920900 cites W2103257412 @default.
- W4282920900 cites W2107587681 @default.
- W4282920900 cites W2111328277 @default.
- W4282920900 cites W2114065017 @default.
- W4282920900 cites W2132872213 @default.
- W4282920900 cites W2139343978 @default.
- W4282920900 cites W2143586703 @default.
- W4282920900 cites W2146548584 @default.
- W4282920900 cites W2148593826 @default.
- W4282920900 cites W2159967578 @default.
- W4282920900 cites W2169000897 @default.
- W4282920900 cites W2169307472 @default.
- W4282920900 cites W2226317100 @default.
- W4282920900 cites W2295236527 @default.
- W4282920900 cites W2315322079 @default.
- W4282920900 cites W2417431203 @default.
- W4282920900 cites W2474739399 @default.
- W4282920900 cites W2582671354 @default.
- W4282920900 cites W2588916311 @default.
- W4282920900 cites W2597045666 @default.
- W4282920900 cites W2603088210 @default.
- W4282920900 cites W2604441970 @default.
- W4282920900 cites W2615326416 @default.
- W4282920900 cites W2616923195 @default.
- W4282920900 cites W2745624257 @default.
- W4282920900 cites W2763670669 @default.
- W4282920900 cites W2767805709 @default.
- W4282920900 cites W2777192533 @default.
- W4282920900 cites W2884890286 @default.
- W4282920900 cites W2889892351 @default.
- W4282920900 cites W2914068327 @default.
- W4282920900 cites W2951188632 @default.
- W4282920900 cites W2951813451 @default.
- W4282920900 cites W2966500633 @default.
- W4282920900 cites W2971737201 @default.
- W4282920900 cites W2994242812 @default.
- W4282920900 cites W3005336040 @default.
- W4282920900 cites W3020107077 @default.
- W4282920900 cites W3087464965 @default.
- W4282920900 cites W3087937382 @default.
- W4282920900 cites W3127912627 @default.
- W4282920900 cites W3154936417 @default.
- W4282920900 cites W3157821912 @default.
- W4282920900 cites W3159797425 @default.
- W4282920900 cites W3164078364 @default.
- W4282920900 cites W3179641925 @default.
- W4282920900 cites W3209393335 @default.
- W4282920900 cites W4200569348 @default.
- W4282920900 cites W4298217633 @default.
- W4282920900 doi "https://doi.org/10.4111/icu.20220061" @default.
- W4282920900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35670004" @default.
- W4282920900 hasPublicationYear "2022" @default.
- W4282920900 type Work @default.
- W4282920900 citedByCount "2" @default.
- W4282920900 countsByYear W42829209002023 @default.
- W4282920900 crossrefType "journal-article" @default.
- W4282920900 hasAuthorship W4282920900A5013052304 @default.
- W4282920900 hasAuthorship W4282920900A5023550307 @default.
- W4282920900 hasBestOaLocation W42829209001 @default.
- W4282920900 hasConcept C121608353 @default.
- W4282920900 hasConcept C126322002 @default.
- W4282920900 hasConcept C134306372 @default.
- W4282920900 hasConcept C143998085 @default.
- W4282920900 hasConcept C159654299 @default.
- W4282920900 hasConcept C197336794 @default.
- W4282920900 hasConcept C203014093 @default.
- W4282920900 hasConcept C2777325958 @default.
- W4282920900 hasConcept C2777701055 @default.
- W4282920900 hasConcept C2780035454 @default.
- W4282920900 hasConcept C2780352672 @default.
- W4282920900 hasConcept C33923547 @default.
- W4282920900 hasConcept C502942594 @default.