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- W4282923018 abstract "In biology, molecular terms with the suffix -omics refer to disciplines aiming at the collective characterization of pools of molecules derived from different layers (DNA, RNA, proteins, metabolites) of living organisms using high-throughput technologies. Such omics analyses have been widely implemented in poultry research in recent years. This first part of a bipartite review on omics technologies in poultry health and productivity examines the use of multiple omics and multi-omics techniques in poultry research. More specific present and future applications of omics technologies, not only for the identification of specific diagnostic biomarkers, but also for potential future integration in the daily monitoring of poultry production, are discussed in part 2. Approaches based on omics technologies are particularly used in poultry research in the hunt for genetic markers of economically important phenotypical traits in the host, and in the identification of key bacterial species or functions in the intestinal microbiome. Integrative multi-omics analyses, however, are still scarce. Host physiology is investigated via genomics together with transcriptomics, proteomics and metabolomics techniques, to understand more accurately complex production traits such as disease resistance and fertility. The gut microbiota, as a key player in chicken productivity and health, is also a main subject of such studies, investigating the association between its composition (16S rRNA gene sequencing) or function (metagenomics, metatranscriptomics, metaproteomics, metabolomics) and host phenotypes. Applications of these technologies in the study of other host-associated microbiota and other host characteristics are still in their infancy." @default.
- W4282923018 created "2022-06-16" @default.
- W4282923018 creator A5007426729 @default.
- W4282923018 creator A5022490551 @default.
- W4282923018 creator A5044653645 @default.
- W4282923018 creator A5089626020 @default.
- W4282923018 date "2022-06-27" @default.
- W4282923018 modified "2023-10-04" @default.
- W4282923018 title "Omics technologies in poultry health and productivity - part 1: current use in poultry research" @default.
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- W4282923018 doi "https://doi.org/10.1080/03079457.2022.2086447" @default.
- W4282923018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35675291" @default.