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• W4282936100 abstract "Hypoxic ischemic brain injury (HIBI) is the predominant cause of morbidity and mortality in patients who survive their initial cardiac arrest. 1. Sandroni C. Cronberg T. Sekhon M. Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis. Intensive Care Med [Internet]. 2021; 47 ([cited 2022 Mar 3]. Available from: https://pubmed.ncbi.nlm.nih.gov/34705079/): 1393-1414 Crossref PubMed Scopus (20) Google Scholar , 2. Sandroni C. D’Arrigo S. Cacciola S. et al. Prediction of poor neurological outcome in comatose survivors of cardiac arrest: a systematic review [Internet]. Intensive Care Med. 2020; 46 ([cited 2021 Apr 18]. Available from: https://pubmed.ncbi.nlm.nih.gov/32915254/): 1803-1851 Crossref PubMed Scopus (69) Google Scholar HIBI is increasingly recognized as a heterogeneous injury, with patients having markedly different anatomic patterns and severity of injury. 1. Sandroni C. Cronberg T. Sekhon M. Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis. Intensive Care Med [Internet]. 2021; 47 ([cited 2022 Mar 3]. Available from: https://pubmed.ncbi.nlm.nih.gov/34705079/): 1393-1414 Crossref PubMed Scopus (20) Google Scholar , 3. Sekhon M.S. Ainslie P.N. Griesdale D.E. Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a “ two-hit ” model. Crit Care. 2017; 21: 1-10 PubMed Google Scholar , 4. Haglund M. Lindberg E. Englund E. Hippocampus and basal ganglia as potential sentinel sites for ischemic pathology after resuscitated cardiac arrest. Resuscitation [Internet]. 2019; 139 (Available from: https://pubmed.ncbi.nlm.nih.gov/31005590/. [cited 2021 Apr 28]): 230-233 Abstract Full Text Full Text PDF PubMed Scopus (5) Google Scholar , 5. Drabek T. Foley L.M. Janata A. et al. Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI. Resuscitation [Internet]. 2014; 85 (Available from: http://www.ncbi.nlm.nih.gov/pubmed/24727136. [cited 2018 Jun 3]): 964-971 Abstract Full Text Full Text PDF PubMed Scopus (49) Google Scholar This is partly attributable to between-patient differences in both cerebrovascular physiology, 6. Sekhon MS, Gooderham P, Menon DK, et al. The burden of brain hypoxia and optimal mean arterial pressure in patients with hypoxic ischemic brain injury after cardiac arrest. Crit Care Med [Internet] 2019 [cited 2019 Mar 21];1. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30889022. Google Scholar , 7. Sekhon M.S. Griesdale D.E. Ainslie P.N. et al. Intracranial pressure and compliance in hypoxic ischemic brain injury patients after cardiac arrest. Resuscitation. 2019; 141 Abstract Full Text Full Text PDF PubMed Scopus (20) Google Scholar and selective ischemia – reperfusion injury to vulnerable anatomical locations in the cerebrum. 3. Sekhon M.S. Ainslie P.N. Griesdale D.E. Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a “ two-hit ” model. Crit Care. 2017; 21: 1-10 PubMed Google Scholar , 4. Haglund M. Lindberg E. Englund E. Hippocampus and basal ganglia as potential sentinel sites for ischemic pathology after resuscitated cardiac arrest. Resuscitation [Internet]. 2019; 139 (Available from: https://pubmed.ncbi.nlm.nih.gov/31005590/. [cited 2021 Apr 28]): 230-233 Abstract Full Text Full Text PDF PubMed Scopus (5) Google Scholar , 8. Hossmann K.A. Oschlies U. Schwindt W. Krep H. Electron microscopic investigation of rat brain after brief cardiac arrest. Acta Neuropathol [Internet]. 2001; 101 (Available from: http://www.ncbi.nlm.nih.gov/pubmed/11271364. [cited 2016 Oct 18]): 101-113 Crossref PubMed Scopus (42) Google Scholar , 9. Drabek T. Foley L.M. Janata A. et al. Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI. Resuscitation [Internet]. 2014; 85 (Available from: https://pubmed.ncbi.nlm.nih.gov/24727136/. [cited 2021 Apr 28]): 964-971 Abstract Full Text Full Text PDF PubMed Scopus (50) Google Scholar , 10. Putzu A. Valtorta S. Di Grigoli G. et al. Regional differences in cerebral glucose metabolism after cardiac arrest and resuscitation in rats using [18F]FDG positron emission tomography and autoradiography. Neurocrit Care [Internet]. 2018; 28 (Available from: https://pubmed.ncbi.nlm.nih.gov/28875429/. [cited 2021 Apr 28]): 370-378 Crossref PubMed Scopus (14) Google Scholar Further understanding the intricacies and time course of HIBI pathophysiology, including neuroimaging patterns of injury, may help guide both personalized resuscitation strategies, and support progress of advances in neurological prognostication." @default.
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• W4282936100 date "2022-07-01" @default.
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• W4282936100 title "Low field magnetic resonance imaging: A “beds-eye-d” view into hypoxic ischemic brain injury after cardiac arrest" @default.
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• W4282936100 doi "https://doi.org/10.1016/j.resuscitation.2022.05.010" @default.
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