FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282941489> ?p ?o ?g. }

• W4282941489 endingPage "153473542211054" @default.
• W4282941489 startingPage "153473542211054" @default.
• W4282941489 abstract "Background: Chemotherapy-induced adverse effects (CIAEs) remain a challenging problem due to their high incidences and negative impacts on treatment in Chinese colorectal cancer (CRC) patients. We aimed to identify risk factors and predictive markers for CIAEs using food/nutrition data in CRC patients receiving post-operative capecitabine-based chemotherapy. Methods: Food/nutrition data from 130 Chinese CRC patients were analyzed. Univariate and multivariate analyses were used to identify CIAE-related food/nutrition factors. Prediction models were constructed based on the combination of these factors. The area under the receiver operating characteristic curve (AUROC) was used to evaluate the discrimination ability of models. Results: A total of 20 food/nutrition factors associated with CIAEs were identified in the univariate analysis after adjustments for total energy and potential confounding factors. Based on multivariate analysis, we found that, among these factors, dessert, eggs, poultry, and milk were associated with several CIAEs. Most importantly, poultry was an overall protective factor; milk and egg were risk factors for hand-foot syndrome (HFS) and bone marrow suppression (BMS), respectively. Developed multivariate models in predicting grade 1 to 3 CIAEs and grade 2/3 CIAEs both had good discrimination (AUROC values from 0.671 to 0.778, 0.750 to 0.946 respectively), which had potential clinical application value in the early prediction of CIAEs, especially for more severe CIAEs. Conclusions: Our findings suggest that patients with high milk and egg intakes should be clinically instructed to control their corresponding dietary intake to reduce the likelihood of developing HFS and BMS during capecitabine-based chemotherapy, respectively. Trial registration: ClinicalTrials.gov Identifier: NCT03030508." @default.
• W4282941489 created "2022-06-16" @default.
• W4282941489 creator A5003130726 @default.
• W4282941489 creator A5013763730 @default.
• W4282941489 creator A5024857104 @default.
• W4282941489 creator A5046534462 @default.
• W4282941489 creator A5049396596 @default.
• W4282941489 creator A5057209439 @default.
• W4282941489 creator A5058507445 @default.
• W4282941489 creator A5060708223 @default.
• W4282941489 creator A5060809690 @default.
• W4282941489 creator A5061346816 @default.
• W4282941489 creator A5065037360 @default.
• W4282941489 creator A5071694046 @default.
• W4282941489 creator A5071908720 @default.
• W4282941489 creator A5082571641 @default.
• W4282941489 creator A5088262018 @default.
• W4282941489 date "2022-01-01" @default.
• W4282941489 modified "2023-10-16" @default.
• W4282941489 title "Milk and Egg Are Risk Factors for Adverse Effects of Capecitabine-Based Chemotherapy in Chinese Colorectal Cancer Patients" @default.
• W4282941489 cites W1245295209 @default.
• W4282941489 cites W1502664876 @default.
• W4282941489 cites W1529422432 @default.
• W4282941489 cites W1767177186 @default.
• W4282941489 cites W1913769707 @default.
• W4282941489 cites W1966452335 @default.
• W4282941489 cites W1978683461 @default.
• W4282941489 cites W2026862737 @default.
• W4282941489 cites W2033883349 @default.
• W4282941489 cites W2048837830 @default.
• W4282941489 cites W2052730253 @default.
• W4282941489 cites W2053622367 @default.
• W4282941489 cites W2065253498 @default.
• W4282941489 cites W2096138651 @default.
• W4282941489 cites W2113468729 @default.
• W4282941489 cites W2135498562 @default.
• W4282941489 cites W2149236738 @default.
• W4282941489 cites W2165394247 @default.
• W4282941489 cites W2166359686 @default.
• W4282941489 cites W2171045400 @default.
• W4282941489 cites W2188229458 @default.
• W4282941489 cites W2224137722 @default.
• W4282941489 cites W2435207118 @default.
• W4282941489 cites W2514106337 @default.
• W4282941489 cites W2550889281 @default.
• W4282941489 cites W2734832333 @default.
• W4282941489 cites W2792483243 @default.
• W4282941489 cites W2793044932 @default.
• W4282941489 cites W2795907272 @default.
• W4282941489 cites W2797024694 @default.
• W4282941489 cites W2802433006 @default.
• W4282941489 cites W2804675995 @default.
• W4282941489 cites W2866614490 @default.
• W4282941489 cites W2889316871 @default.
• W4282941489 cites W2889646458 @default.
• W4282941489 cites W2927381754 @default.
• W4282941489 cites W2937141947 @default.
• W4282941489 cites W2945285297 @default.
• W4282941489 cites W2945666013 @default.
• W4282941489 cites W2945820321 @default.
• W4282941489 cites W2946925417 @default.
• W4282941489 cites W2948311707 @default.
• W4282941489 cites W2953392140 @default.
• W4282941489 cites W2979492738 @default.
• W4282941489 cites W3042787349 @default.
• W4282941489 cites W3082957029 @default.
• W4282941489 cites W3095068451 @default.
• W4282941489 cites W3176616236 @default.
• W4282941489 cites W3187378970 @default.
• W4282941489 cites W3197575676 @default.
• W4282941489 cites W4214893633 @default.
• W4282941489 doi "https://doi.org/10.1177/15347354221105485" @default.
• W4282941489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35686441" @default.
• W4282941489 hasPublicationYear "2022" @default.
• W4282941489 type Work @default.
• W4282941489 citedByCount "2" @default.
• W4282941489 countsByYear W42829414892022 @default.
• W4282941489 countsByYear W42829414892023 @default.
• W4282941489 crossrefType "journal-article" @default.
• W4282941489 hasAuthorship W4282941489A5003130726 @default.
• W4282941489 hasAuthorship W4282941489A5013763730 @default.
• W4282941489 hasAuthorship W4282941489A5024857104 @default.
• W4282941489 hasAuthorship W4282941489A5046534462 @default.
• W4282941489 hasAuthorship W4282941489A5049396596 @default.
• W4282941489 hasAuthorship W4282941489A5057209439 @default.
• W4282941489 hasAuthorship W4282941489A5058507445 @default.
• W4282941489 hasAuthorship W4282941489A5060708223 @default.
• W4282941489 hasAuthorship W4282941489A5060809690 @default.
• W4282941489 hasAuthorship W4282941489A5061346816 @default.
• W4282941489 hasAuthorship W4282941489A5065037360 @default.
• W4282941489 hasAuthorship W4282941489A5071694046 @default.
• W4282941489 hasAuthorship W4282941489A5071908720 @default.
• W4282941489 hasAuthorship W4282941489A5082571641 @default.
• W4282941489 hasAuthorship W4282941489A5088262018 @default.
• W4282941489 hasBestOaLocation W42829414891 @default.
• W4282941489 hasConcept C105795698 @default.
• W4282941489 hasConcept C121608353 @default.
• W4282941489 hasConcept C126322002 @default.

• next