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- W4282943313 abstract "Four highly oxygenated sesquiterpenoids, illimicranolides A (1) and B (2), and illicinolides E (3) and F (4), were obtained from the fruits of Illicium micranthum Dunn, as well as one known analog, illicinolide B (5). The chemical structures of 1-4 were determined comprehensively by 1D (1 H and 13 C) and 2D (HMBC, HSQC, 1 H-1 H COSY, and ROESY) NMR, and HR-ESI-MS data. Structurally, compound 1 was an unprecedented sesquiterpenoid with a 5/5/6/5-fused tetracyclic ring system and was the first seco-prezizaane sesquiterpenoid featuring a 11,8-γ-lactone ring. Compounds 3 and 4 were the fifth and sixth examples of illicinolide-type sesquiterpenoids. Moreover, compound 1 demonstrated neurotrophic activity of NGF-induced PC12 cells with differentiation rate of 10.34 % at a concentration of 10 μM." @default.
- W4282943313 created "2022-06-16" @default.
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- W4282943313 date "2022-06-15" @default.
- W4282943313 modified "2023-10-16" @default.
- W4282943313 title "Four Highly Oxygenated Sesquiterpenoids from the Fruits of <i>Illicium micranthum</i> Dunn" @default.
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- W4282943313 doi "https://doi.org/10.1002/cbdv.202200429" @default.
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