Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282943800> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4282943800 abstract "Autologous plasmin enzyme facilitates the induction of posterior vitreous detachment(PVD) during vitrectomy in young patients. We proposed the concept of in-vivo generated plasmin which is based on the injection of tissue plasminogen activator(t-PA) and autologous whole blood(AWB) into the vitreous cavity. The purpose of this pilot study is to report the efficacy of preoperative simultaneous intravitreal injection of(t-PA) and autologous whole blood in facilitating the intraoperative induction of PVD in young patients with various vitreoretinal pathologies.Seventeen eyes of 16 young patients with various vitreoretinal pathologies requiring vitrectomy, who received simultaneous intravitreal injection of 0.1 ml of AWB and 25 µg of t-PA, 3 days prior to surgery were retrospectively reviewed. Outcome measures were the number of attempts required to achieve successful intraoperative separation of the posterior hyaloid; the postoperative visual acuity; and intraoperative and postoperative complications.The mean age of the patients was 23.87 ± 10.09 years, ranging from 10 to 39 years. Eight of 16 patients were men. The mean follow-up time was 19.35 ± 5.04 months, ranging from 12 to 26 months. Surgical indications for vitrectomy were chronic retinal detachment (n = 7), traumatic retinal detachment without proliferative vitreoretinopathy(n = 3), traumatic macular hole(n = 1), secondary vasoproliferative tumor(n = 4) and optic pit maculopathy(n = 2). Patients with retinal detachment complicated with PVR and those who were older than 40 years of age were excluded from the study. Separation of the Weiss ring from the optic nerve head was achieved intraoperatively in all cases, with a mean number of 2.86 ± 1.4 attempts. While the mean preoperative LogMAR visual acuity was 1.38 ± 0.59, ranging from 2.40 to 0.50, it was a mean of 0.51 ± 0.29, ranging from 1.00 to 0.10 at final postoperative exam(p < 0.001; paired samples t-test). No preoperative or intraoperative complications were noted.Preoperative simultaneous intravitreal injection of 25 µg t-PA with 0.1 ml of AWB facilitates the intraoperative induction of posterior vitreous detachment in young patients." @default.
- W4282943800 created "2022-06-16" @default.
- W4282943800 creator A5032748319 @default.
- W4282943800 creator A5046958282 @default.
- W4282943800 creator A5059531052 @default.
- W4282943800 creator A5064513171 @default.
- W4282943800 creator A5066607918 @default.
- W4282943800 creator A5081654477 @default.
- W4282943800 date "2022-06-11" @default.
- W4282943800 modified "2023-10-12" @default.
- W4282943800 title "In vivo generated autologous plasmin assisted vitrectomy in young patients" @default.
- W4282943800 cites W1748435277 @default.
- W4282943800 cites W1967417070 @default.
- W4282943800 cites W1972783723 @default.
- W4282943800 cites W1979357731 @default.
- W4282943800 cites W1982066606 @default.
- W4282943800 cites W1999134848 @default.
- W4282943800 cites W2039630204 @default.
- W4282943800 cites W2051427766 @default.
- W4282943800 cites W2074140561 @default.
- W4282943800 cites W2083381407 @default.
- W4282943800 cites W2162522012 @default.
- W4282943800 cites W2272091952 @default.
- W4282943800 cites W2313778376 @default.
- W4282943800 cites W2332257065 @default.
- W4282943800 cites W2430215425 @default.
- W4282943800 doi "https://doi.org/10.1186/s40942-022-00391-3" @default.
- W4282943800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35690857" @default.
- W4282943800 hasPublicationYear "2022" @default.
- W4282943800 type Work @default.
- W4282943800 citedByCount "1" @default.
- W4282943800 countsByYear W42829438002023 @default.
- W4282943800 crossrefType "journal-article" @default.
- W4282943800 hasAuthorship W4282943800A5032748319 @default.
- W4282943800 hasAuthorship W4282943800A5046958282 @default.
- W4282943800 hasAuthorship W4282943800A5059531052 @default.
- W4282943800 hasAuthorship W4282943800A5064513171 @default.
- W4282943800 hasAuthorship W4282943800A5066607918 @default.
- W4282943800 hasAuthorship W4282943800A5081654477 @default.
- W4282943800 hasBestOaLocation W42829438001 @default.
- W4282943800 hasConcept C118487528 @default.
- W4282943800 hasConcept C134018914 @default.
- W4282943800 hasConcept C141071460 @default.
- W4282943800 hasConcept C181199279 @default.
- W4282943800 hasConcept C185592680 @default.
- W4282943800 hasConcept C2777063560 @default.
- W4282943800 hasConcept C2778257484 @default.
- W4282943800 hasConcept C2778313320 @default.
- W4282943800 hasConcept C2779059073 @default.
- W4282943800 hasConcept C2779676219 @default.
- W4282943800 hasConcept C2780428090 @default.
- W4282943800 hasConcept C2780827179 @default.
- W4282943800 hasConcept C2780837183 @default.
- W4282943800 hasConcept C2781071845 @default.
- W4282943800 hasConcept C2781116099 @default.
- W4282943800 hasConcept C2781242345 @default.
- W4282943800 hasConcept C55493867 @default.
- W4282943800 hasConcept C555293320 @default.
- W4282943800 hasConcept C71924100 @default.
- W4282943800 hasConceptScore W4282943800C118487528 @default.
- W4282943800 hasConceptScore W4282943800C134018914 @default.
- W4282943800 hasConceptScore W4282943800C141071460 @default.
- W4282943800 hasConceptScore W4282943800C181199279 @default.
- W4282943800 hasConceptScore W4282943800C185592680 @default.
- W4282943800 hasConceptScore W4282943800C2777063560 @default.
- W4282943800 hasConceptScore W4282943800C2778257484 @default.
- W4282943800 hasConceptScore W4282943800C2778313320 @default.
- W4282943800 hasConceptScore W4282943800C2779059073 @default.
- W4282943800 hasConceptScore W4282943800C2779676219 @default.
- W4282943800 hasConceptScore W4282943800C2780428090 @default.
- W4282943800 hasConceptScore W4282943800C2780827179 @default.
- W4282943800 hasConceptScore W4282943800C2780837183 @default.
- W4282943800 hasConceptScore W4282943800C2781071845 @default.
- W4282943800 hasConceptScore W4282943800C2781116099 @default.
- W4282943800 hasConceptScore W4282943800C2781242345 @default.
- W4282943800 hasConceptScore W4282943800C55493867 @default.
- W4282943800 hasConceptScore W4282943800C555293320 @default.
- W4282943800 hasConceptScore W4282943800C71924100 @default.
- W4282943800 hasIssue "1" @default.
- W4282943800 hasLocation W42829438001 @default.
- W4282943800 hasLocation W42829438002 @default.
- W4282943800 hasLocation W42829438003 @default.
- W4282943800 hasOpenAccess W4282943800 @default.
- W4282943800 hasPrimaryLocation W42829438001 @default.
- W4282943800 hasRelatedWork W1125252616 @default.
- W4282943800 hasRelatedWork W1141892779 @default.
- W4282943800 hasRelatedWork W1491559433 @default.
- W4282943800 hasRelatedWork W1965842590 @default.
- W4282943800 hasRelatedWork W2037726479 @default.
- W4282943800 hasRelatedWork W2057273353 @default.
- W4282943800 hasRelatedWork W2080429348 @default.
- W4282943800 hasRelatedWork W2104573479 @default.
- W4282943800 hasRelatedWork W2146755607 @default.
- W4282943800 hasRelatedWork W4321501205 @default.
- W4282943800 hasVolume "8" @default.
- W4282943800 isParatext "false" @default.
- W4282943800 isRetracted "false" @default.
- W4282943800 workType "article" @default.