Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282959091> ?p ?o ?g. }
- W4282959091 endingPage "105643" @default.
- W4282959091 startingPage "105643" @default.
- W4282959091 abstract "Cronobacter species have adapted to survive harsh conditions, particularly in the food manufacture environment, and can cause life-threatening infections in susceptible hosts. These opportunistic pathogens employ a multitude of mechanisms to aid their virulence throughout three key stages: environmental persistence, infection strategy, and systemic persistence in the human host. Environmental persistence is aided by the formation of biofilms, development of subpopulations, and high tolerance to environmental stressors. Successful infection in the human host involves several mechanisms such as protein secretion, motility, quorum sensing, colonisation, and translocation. Survival inside the host is achieved via competitive acquisition and utilization of minerals and metabolites respectively, coupled with host immune system evasion and antimicrobial resistance (AMR) mechanisms. Across the globe, Cronobacter sakazakii is associated with often fatal systemic infections in populations including neonates, infants, the elderly and the immunocompromised. By providing insight into the mechanisms of virulence utilised by this pathogen across these three stages, this review identifies current gaps in the literature. Further research into these virulence mechanisms is required to inform novel mitigation measures to improve global food safety with regards to this food-borne pathogen." @default.
- W4282959091 created "2022-06-17" @default.
- W4282959091 creator A5002509043 @default.
- W4282959091 creator A5006981180 @default.
- W4282959091 creator A5010067550 @default.
- W4282959091 creator A5033864999 @default.
- W4282959091 creator A5057497270 @default.
- W4282959091 date "2022-08-01" @default.
- W4282959091 modified "2023-10-07" @default.
- W4282959091 title "Insights into the mechanisms of Cronobacter sakazakii virulence" @default.
- W4282959091 cites W1816481481 @default.
- W4282959091 cites W1909267167 @default.
- W4282959091 cites W1911657064 @default.
- W4282959091 cites W1964954110 @default.
- W4282959091 cites W1968642994 @default.
- W4282959091 cites W1970035873 @default.
- W4282959091 cites W1985016787 @default.
- W4282959091 cites W2009163271 @default.
- W4282959091 cites W2015120914 @default.
- W4282959091 cites W2022043295 @default.
- W4282959091 cites W2022173246 @default.
- W4282959091 cites W2039985444 @default.
- W4282959091 cites W2040377484 @default.
- W4282959091 cites W2044638935 @default.
- W4282959091 cites W2058147218 @default.
- W4282959091 cites W2062385531 @default.
- W4282959091 cites W2071602596 @default.
- W4282959091 cites W2073433901 @default.
- W4282959091 cites W2098953976 @default.
- W4282959091 cites W2113484670 @default.
- W4282959091 cites W2119703950 @default.
- W4282959091 cites W2123595241 @default.
- W4282959091 cites W2129733944 @default.
- W4282959091 cites W2137868616 @default.
- W4282959091 cites W2145853372 @default.
- W4282959091 cites W2150886887 @default.
- W4282959091 cites W2163455067 @default.
- W4282959091 cites W2165286432 @default.
- W4282959091 cites W2177127924 @default.
- W4282959091 cites W2200674944 @default.
- W4282959091 cites W2229240186 @default.
- W4282959091 cites W2299009003 @default.
- W4282959091 cites W2337380722 @default.
- W4282959091 cites W2470317900 @default.
- W4282959091 cites W2515065092 @default.
- W4282959091 cites W2576519196 @default.
- W4282959091 cites W2577860002 @default.
- W4282959091 cites W2674367379 @default.
- W4282959091 cites W2752941172 @default.
- W4282959091 cites W2769115608 @default.
- W4282959091 cites W2786216345 @default.
- W4282959091 cites W2787960517 @default.
- W4282959091 cites W2790542614 @default.
- W4282959091 cites W2885252153 @default.
- W4282959091 cites W2886168131 @default.
- W4282959091 cites W2886729042 @default.
- W4282959091 cites W2887056633 @default.
- W4282959091 cites W2891878919 @default.
- W4282959091 cites W2894349863 @default.
- W4282959091 cites W2897267968 @default.
- W4282959091 cites W2914767984 @default.
- W4282959091 cites W2921077192 @default.
- W4282959091 cites W2947586205 @default.
- W4282959091 cites W2947989036 @default.
- W4282959091 cites W3001033076 @default.
- W4282959091 cites W3004497541 @default.
- W4282959091 cites W3005472374 @default.
- W4282959091 cites W3006869114 @default.
- W4282959091 cites W3011327629 @default.
- W4282959091 cites W3017230949 @default.
- W4282959091 cites W3026328808 @default.
- W4282959091 cites W3045080755 @default.
- W4282959091 cites W3081294242 @default.
- W4282959091 cites W3082950745 @default.
- W4282959091 cites W3083901664 @default.
- W4282959091 cites W3088763038 @default.
- W4282959091 cites W3094752896 @default.
- W4282959091 cites W3118350936 @default.
- W4282959091 cites W3119026287 @default.
- W4282959091 cites W3124061919 @default.
- W4282959091 cites W3174906778 @default.
- W4282959091 cites W3176891160 @default.
- W4282959091 cites W4200223659 @default.
- W4282959091 cites W4223467617 @default.
- W4282959091 cites W4224217718 @default.
- W4282959091 cites W3080933269 @default.
- W4282959091 doi "https://doi.org/10.1016/j.micpath.2022.105643" @default.
- W4282959091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35716925" @default.
- W4282959091 hasPublicationYear "2022" @default.
- W4282959091 type Work @default.
- W4282959091 citedByCount "9" @default.
- W4282959091 countsByYear W42829590912022 @default.
- W4282959091 countsByYear W42829590912023 @default.
- W4282959091 crossrefType "journal-article" @default.
- W4282959091 hasAuthorship W4282959091A5002509043 @default.
- W4282959091 hasAuthorship W4282959091A5006981180 @default.
- W4282959091 hasAuthorship W4282959091A5010067550 @default.
- W4282959091 hasAuthorship W4282959091A5033864999 @default.