FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282959598> ?p ?o ?g. }

• W4282959598 abstract "Abstract Background Available literature indicates that long-term drinkers demand a higher dose of propofol for induction of anesthesia than non-drinkers. However, there is no study having assessed the influence of long-term high-risk drinking (LTHRD) on the effective doses of propofol for successful insertion of gastroscope with sedation. This study was designed to compare the effective doses of propofol for successful insertion of gastroscope between LTHRD and non-drinking (ND) Chinese male patients. Methods Thirty-one LTHRD patients and 29 ND male patients undergoing elective gastroscopy with propofol sedation were enrolled. The modified Dixon’s up-and-down method was applied to determine the calculated median effective dose (ED 50 ) of propofol for successful insertion of gastroscope. Furthermore, the isotonic regression analysis was used to establish the dose–response curve of propofol and assess the effective doses of propofol where 50% (ED 50 ) and 95% (ED 95 ) of gastroscope insertions were successful. Results The calculated ED 50 of propofol for successful insertion of gastroscope was 1.55 ± 0.10 mg/kg and 1.44 ± 0.11 mg/kg in the LTHRD and ND patients. The isotonic regression analysis further showed that ED 50 and ED 95 of propofol for successful insertion of gastroscope was 1.50 mg/kg (95%CI, 1.40–1.63) and 1.80 mg/kg (95%CI, 1.74–1.90) in the LTHRD patients, respectively; 1.40 mg/kg (95% CI, 1.27–1.57) and 1.60 mg/kg (95%CI, 1.56–1.65) in the ND patients. The ED 50 of propofol for successful insertion of gastroscope was not significantly different between LTHRD and ND patients. Conclusions This study demonstrates that the difference in the estimated ED 50 of propofol for successful insertion of gastroscope between LTHRD and ND Chinese male patients was not statistically significant. Trial registration The study was registered on November 28, 2020 ( ChiCTR2000040382 ) in the Chinese Clinical Trial Registry." @default.
• W4282959598 created "2022-06-17" @default.
• W4282959598 creator A5000077691 @default.
• W4282959598 creator A5025259969 @default.
• W4282959598 creator A5029117931 @default.
• W4282959598 creator A5038626671 @default.
• W4282959598 creator A5048643630 @default.
• W4282959598 creator A5070664219 @default.
• W4282959598 creator A5081492088 @default.
• W4282959598 date "2022-06-16" @default.
• W4282959598 modified "2023-10-09" @default.
• W4282959598 title "Long-term high-risk drinking does not change effective doses of propofol for successful insertion of gastroscope in Chinese male patients" @default.
• W4282959598 cites W1904400366 @default.
• W4282959598 cites W1973798824 @default.
• W4282959598 cites W1978972772 @default.
• W4282959598 cites W1981742453 @default.
• W4282959598 cites W1992937713 @default.
• W4282959598 cites W2017523686 @default.
• W4282959598 cites W2026317925 @default.
• W4282959598 cites W2035563993 @default.
• W4282959598 cites W2046367649 @default.
• W4282959598 cites W2049349314 @default.
• W4282959598 cites W2056494616 @default.
• W4282959598 cites W2070961932 @default.
• W4282959598 cites W2082071339 @default.
• W4282959598 cites W2083530799 @default.
• W4282959598 cites W2099484705 @default.
• W4282959598 cites W2148565298 @default.
• W4282959598 cites W2159542589 @default.
• W4282959598 cites W2171999085 @default.
• W4282959598 cites W2172422824 @default.
• W4282959598 cites W2576390257 @default.
• W4282959598 cites W2589026107 @default.
• W4282959598 cites W2768712393 @default.
• W4282959598 cites W2793506004 @default.
• W4282959598 cites W2799535453 @default.
• W4282959598 cites W2893961115 @default.
• W4282959598 cites W2900706898 @default.
• W4282959598 cites W2955063694 @default.
• W4282959598 cites W2985254366 @default.
• W4282959598 cites W3025029024 @default.
• W4282959598 cites W3087565978 @default.
• W4282959598 cites W3101776042 @default.
• W4282959598 cites W85125531 @default.
• W4282959598 cites W2170674536 @default.
• W4282959598 doi "https://doi.org/10.1186/s12871-022-01725-2" @default.
• W4282959598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35710328" @default.
• W4282959598 hasPublicationYear "2022" @default.
• W4282959598 type Work @default.
• W4282959598 citedByCount "0" @default.
• W4282959598 crossrefType "journal-article" @default.
• W4282959598 hasAuthorship W4282959598A5000077691 @default.
• W4282959598 hasAuthorship W4282959598A5025259969 @default.
• W4282959598 hasAuthorship W4282959598A5029117931 @default.
• W4282959598 hasAuthorship W4282959598A5038626671 @default.
• W4282959598 hasAuthorship W4282959598A5048643630 @default.
• W4282959598 hasAuthorship W4282959598A5070664219 @default.
• W4282959598 hasAuthorship W4282959598A5081492088 @default.
• W4282959598 hasBestOaLocation W42829595981 @default.
• W4282959598 hasConcept C2776277131 @default.
• W4282959598 hasConcept C2776814716 @default.
• W4282959598 hasConcept C2779526319 @default.
• W4282959598 hasConcept C42219234 @default.
• W4282959598 hasConcept C71924100 @default.
• W4282959598 hasConceptScore W4282959598C2776277131 @default.
• W4282959598 hasConceptScore W4282959598C2776814716 @default.
• W4282959598 hasConceptScore W4282959598C2779526319 @default.
• W4282959598 hasConceptScore W4282959598C42219234 @default.
• W4282959598 hasConceptScore W4282959598C71924100 @default.
• W4282959598 hasIssue "1" @default.
• W4282959598 hasLocation W42829595981 @default.
• W4282959598 hasLocation W42829595982 @default.
• W4282959598 hasLocation W42829595983 @default.
• W4282959598 hasOpenAccess W4282959598 @default.
• W4282959598 hasPrimaryLocation W42829595981 @default.
• W4282959598 hasRelatedWork W163357817 @default.
• W4282959598 hasRelatedWork W1985198936 @default.
• W4282959598 hasRelatedWork W2001683931 @default.
• W4282959598 hasRelatedWork W20440739 @default.
• W4282959598 hasRelatedWork W2046685379 @default.
• W4282959598 hasRelatedWork W2361468386 @default.
• W4282959598 hasRelatedWork W2373888550 @default.
• W4282959598 hasRelatedWork W2377505480 @default.
• W4282959598 hasRelatedWork W67055460 @default.
• W4282959598 hasRelatedWork W2184511288 @default.
• W4282959598 hasVolume "22" @default.
• W4282959598 isParatext "false" @default.
• W4282959598 isRetracted "false" @default.
• W4282959598 workType "article" @default.