Matches in SemOpenAlex for { <https://semopenalex.org/work/W4282975303> ?p ?o ?g. }
- W4282975303 endingPage "8" @default.
- W4282975303 startingPage "1" @default.
- W4282975303 abstract "White matter hyperintensities (WMH), a marker of small vessel cerebrovascular disease, increase risk of developing mild cognitive impairment (MCI) and Alzheimer's disease (AD). Less is known about the extent and pattern of WMH in pre-MCI stages, such as among those with objectively-defined subtle cognitive decline (Obj-SCD). Five hundred and fifty-nine Alzheimer's Disease Neuroimaging Initiative participants (170 cognitively unimpaired [CU]; 83 Obj-SCD; 306 MCI) free of clinical dementia or stroke completed neuropsychological testing and MRI exams. ANCOVA models compared cognitive groups on regional WMH adjusting for age, sex, and apolipoprotein E (APOE) ɛ4 frequency. Compared with the CU group, those with Obj-SCD had greater temporal, occipital, and frontal WMH whereas those with MCI had higher WMH volume across all regions (p’s < 0.01). No differences in WMH volume were observed between the Obj-SCD and MCI groups (p’s > 0.05). Findings add to growing evidence of associations between Obj-SCD and imaging biomarkers, providing support for utility of these criteria to capture subtle cognitive changes that are biologically based." @default.
- W4282975303 created "2022-06-17" @default.
- W4282975303 creator A5001429661 @default.
- W4282975303 creator A5008069233 @default.
- W4282975303 creator A5008248969 @default.
- W4282975303 creator A5009639179 @default.
- W4282975303 creator A5030310675 @default.
- W4282975303 creator A5053593690 @default.
- W4282975303 creator A5055254219 @default.
- W4282975303 creator A5061684791 @default.
- W4282975303 creator A5065570919 @default.
- W4282975303 creator A5074790609 @default.
- W4282975303 creator A5091360737 @default.
- W4282975303 date "2022-10-01" @default.
- W4282975303 modified "2023-10-17" @default.
- W4282975303 title "Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment" @default.
- W4282975303 cites W1523320996 @default.
- W4282975303 cites W1526060982 @default.
- W4282975303 cites W1544359545 @default.
- W4282975303 cites W1583631062 @default.
- W4282975303 cites W1847168837 @default.
- W4282975303 cites W1971548649 @default.
- W4282975303 cites W1991952617 @default.
- W4282975303 cites W1996440065 @default.
- W4282975303 cites W2006035554 @default.
- W4282975303 cites W2006859518 @default.
- W4282975303 cites W2006907540 @default.
- W4282975303 cites W2008854521 @default.
- W4282975303 cites W2010814238 @default.
- W4282975303 cites W2017146561 @default.
- W4282975303 cites W2018007042 @default.
- W4282975303 cites W2019047027 @default.
- W4282975303 cites W2020139159 @default.
- W4282975303 cites W2029926470 @default.
- W4282975303 cites W2031762899 @default.
- W4282975303 cites W2045310766 @default.
- W4282975303 cites W2045321639 @default.
- W4282975303 cites W2051159072 @default.
- W4282975303 cites W2058161128 @default.
- W4282975303 cites W2071184036 @default.
- W4282975303 cites W2078524519 @default.
- W4282975303 cites W2099360540 @default.
- W4282975303 cites W2113576511 @default.
- W4282975303 cites W2118900259 @default.
- W4282975303 cites W2126999263 @default.
- W4282975303 cites W2136210722 @default.
- W4282975303 cites W2148080316 @default.
- W4282975303 cites W2156717321 @default.
- W4282975303 cites W2167311298 @default.
- W4282975303 cites W2168818001 @default.
- W4282975303 cites W2309640507 @default.
- W4282975303 cites W2325401428 @default.
- W4282975303 cites W2527609605 @default.
- W4282975303 cites W2763243272 @default.
- W4282975303 cites W2790256563 @default.
- W4282975303 cites W2806714705 @default.
- W4282975303 cites W2959125974 @default.
- W4282975303 cites W2986743150 @default.
- W4282975303 cites W2998178149 @default.
- W4282975303 cites W3039890225 @default.
- W4282975303 cites W3087558871 @default.
- W4282975303 cites W3155371527 @default.
- W4282975303 cites W3170899733 @default.
- W4282975303 cites W3173583997 @default.
- W4282975303 cites W3203966537 @default.
- W4282975303 cites W3206313727 @default.
- W4282975303 doi "https://doi.org/10.1016/j.neurobiolaging.2022.06.002" @default.
- W4282975303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35809348" @default.
- W4282975303 hasPublicationYear "2022" @default.
- W4282975303 type Work @default.
- W4282975303 citedByCount "5" @default.
- W4282975303 countsByYear W42829753032023 @default.
- W4282975303 crossrefType "journal-article" @default.
- W4282975303 hasAuthorship W4282975303A5001429661 @default.
- W4282975303 hasAuthorship W4282975303A5008069233 @default.
- W4282975303 hasAuthorship W4282975303A5008248969 @default.
- W4282975303 hasAuthorship W4282975303A5009639179 @default.
- W4282975303 hasAuthorship W4282975303A5030310675 @default.
- W4282975303 hasAuthorship W4282975303A5053593690 @default.
- W4282975303 hasAuthorship W4282975303A5055254219 @default.
- W4282975303 hasAuthorship W4282975303A5061684791 @default.
- W4282975303 hasAuthorship W4282975303A5065570919 @default.
- W4282975303 hasAuthorship W4282975303A5074790609 @default.
- W4282975303 hasAuthorship W4282975303A5091360737 @default.
- W4282975303 hasBestOaLocation W42829753031 @default.
- W4282975303 hasConcept C126322002 @default.
- W4282975303 hasConcept C126838900 @default.
- W4282975303 hasConcept C127413603 @default.
- W4282975303 hasConcept C14216870 @default.
- W4282975303 hasConcept C143409427 @default.
- W4282975303 hasConcept C146638467 @default.
- W4282975303 hasConcept C15744967 @default.
- W4282975303 hasConcept C164705383 @default.
- W4282975303 hasConcept C169760540 @default.
- W4282975303 hasConcept C169900460 @default.
- W4282975303 hasConcept C185711340 @default.
- W4282975303 hasConcept C2779134260 @default.
- W4282975303 hasConcept C2779483572 @default.