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- W4282976250 abstract "We described clinical characteristics and outcome of 160 patients over 65 years (01 September to 31 August 2021) who had a first positive SARS-CoV-2 PCR- test more than 14 days after full vaccination and were hospitalized with COVID-19. Median age of included patients was 84 years, 61.2% were over 80 years; 50.6% were male and most (82.5%) has at least one comorbidity. Up to 84% received specific treatment against COVID-19, including 76.9% low-flow oxygen therapy. We found that overall mortality was 25.6% and 30.6% in those older than 80 years. A higher mortality was significantly associated with older age and treatment with tocilizumab. Our data showed that although COVID-19 vaccines continue protecting elderly patients against hospitalization and death and might improve the prognosis after hospitalization in patients with breakthrough infections, mortality in this population -especially in those older than 80 years- remains very high." @default.
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- W4282976250 date "2022-07-01" @default.
- W4282976250 modified "2023-10-14" @default.
- W4282976250 title "Clinical characteristics and outcome of hospitalized elderly patients with COVID- 19 after vaccine failure" @default.
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- W4282976250 doi "https://doi.org/10.1016/j.vaccine.2022.06.003" @default.
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