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- W4282983105 abstract "1. Methods are described for the determination of acetophenetidin and p-phenetidin in biological fluids and tissues. 2. The route of metabolism of acetophenetidin in man is as follows: the major fraction of the drug is rapidly deethylated to N-acetyl p-aminophenol; this compound is excreted in a conjugated form; a minor fraction deacetylates to form p-phenetidin; this compound was shown to be the precursor of the substance which oxidizes hemoglobin to methemoglobin. The analgesic and antipyretic action of acetophenetidin is exerted mainly through N-acetyl p-aminophenol which is an active analgesic and antipyretic." @default.
- W4282983105 created "2022-06-17" @default.
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- W4282983105 date "2022-06-15" @default.
- W4282983105 modified "2023-10-18" @default.
- W4282983105 title "Highlights from this issue" @default.
- W4282983105 doi "https://doi.org/10.1136/thoraxjnl-2022-219256" @default.
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