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- W4283067187 abstract "Hypoglycemia results from an imbalance between glucose entering the blood compartment and glucose demand, caused by a defect in the mechanisms regulating postprandial glucose homeostasis. Hypoglycemia represents one of the most common metabolic emergencies in childhood, potentially leading to serious neurologic sequelae, including death. Therefore, appropriate investigation of its specific etiology is paramount to provide adequate diagnosis, specific therapy and prevent its recurrence. In the absence of critical samples for biochemical studies, etiological assessment of children with hypoglycemia may include dynamic methods, such as in vivo functional tests, and continuous glucose monitoring. By providing detailed information on actual glucose fluxes in vivo, proof-of-concept studies have illustrated the potential (clinical) application of dynamic stable isotope techniques to define biochemical and clinical phenotypes of inherited metabolic diseases associated with hypoglycemia. According to the textbooks, individuals with glycogen storage disease type I (GSD I) display the most severe hypoglycemia/fasting intolerance. In this review, three dynamic methods are discussed which may be considered during both diagnostic work-up and monitoring of children with hypoglycemia: 1) functional in vivo tests; 2) in vivo metabolic profiling by continuous glucose monitoring (CGM); 3) stable isotope techniques. Future applications and benefits of dynamic methods in children with hypoglycemia are also discussed." @default.
- W4283067187 created "2022-06-19" @default.
- W4283067187 creator A5045355558 @default.
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- W4283067187 date "2022-06-17" @default.
- W4283067187 modified "2023-10-04" @default.
- W4283067187 title "Dynamic Methods for Childhood Hypoglycemia Phenotyping: A Narrative Review" @default.
- W4283067187 cites W114735896 @default.
- W4283067187 cites W1510199728 @default.
- W4283067187 cites W1528076136 @default.
- W4283067187 cites W1585861318 @default.
- W4283067187 cites W1780295155 @default.
- W4283067187 cites W1837104038 @default.
- W4283067187 cites W1920989919 @default.
- W4283067187 cites W1963658191 @default.
- W4283067187 cites W1963765508 @default.
- W4283067187 cites W1967432680 @default.
- W4283067187 cites W1979428255 @default.
- W4283067187 cites W1981968193 @default.
- W4283067187 cites W1984362846 @default.
- W4283067187 cites W1984656213 @default.
- W4283067187 cites W1992605127 @default.
- W4283067187 cites W1993298697 @default.
- W4283067187 cites W1993920527 @default.
- W4283067187 cites W1997955357 @default.
- W4283067187 cites W1998821235 @default.
- W4283067187 cites W1998858187 @default.
- W4283067187 cites W1999154769 @default.
- W4283067187 cites W1999741060 @default.
- W4283067187 cites W2000485864 @default.
- W4283067187 cites W2001479779 @default.
- W4283067187 cites W2009070123 @default.
- W4283067187 cites W2018196073 @default.
- W4283067187 cites W2020765176 @default.
- W4283067187 cites W2023656701 @default.
- W4283067187 cites W202472619 @default.
- W4283067187 cites W2027301063 @default.
- W4283067187 cites W2028582215 @default.
- W4283067187 cites W2039721323 @default.
- W4283067187 cites W2040001895 @default.
- W4283067187 cites W2040505884 @default.
- W4283067187 cites W2044084591 @default.
- W4283067187 cites W2045779490 @default.
- W4283067187 cites W2049826219 @default.
- W4283067187 cites W2063278564 @default.
- W4283067187 cites W2068197074 @default.
- W4283067187 cites W2074905070 @default.
- W4283067187 cites W2087707740 @default.
- W4283067187 cites W2091788799 @default.
- W4283067187 cites W2098508914 @default.
- W4283067187 cites W2099230072 @default.
- W4283067187 cites W2100556140 @default.
- W4283067187 cites W2102006343 @default.
- W4283067187 cites W2107680447 @default.
- W4283067187 cites W2108602633 @default.
- W4283067187 cites W2118354275 @default.
- W4283067187 cites W2135666165 @default.
- W4283067187 cites W2139260293 @default.
- W4283067187 cites W2142470152 @default.
- W4283067187 cites W2144420785 @default.
- W4283067187 cites W2146557873 @default.
- W4283067187 cites W2147354100 @default.
- W4283067187 cites W2153651382 @default.
- W4283067187 cites W2153853635 @default.
- W4283067187 cites W2163295489 @default.
- W4283067187 cites W2166328575 @default.
- W4283067187 cites W2168495890 @default.
- W4283067187 cites W2168726142 @default.
- W4283067187 cites W2171176478 @default.
- W4283067187 cites W2172291827 @default.
- W4283067187 cites W2178122576 @default.
- W4283067187 cites W2178272958 @default.
- W4283067187 cites W2272232453 @default.
- W4283067187 cites W2278129565 @default.
- W4283067187 cites W2287120293 @default.
- W4283067187 cites W2336773168 @default.
- W4283067187 cites W2406065185 @default.
- W4283067187 cites W2512900140 @default.
- W4283067187 cites W2553088136 @default.
- W4283067187 cites W2593527756 @default.
- W4283067187 cites W2606704283 @default.
- W4283067187 cites W2737189499 @default.
- W4283067187 cites W2765709170 @default.
- W4283067187 cites W2771169199 @default.
- W4283067187 cites W2782877314 @default.
- W4283067187 cites W2783695354 @default.
- W4283067187 cites W2789916950 @default.
- W4283067187 cites W2793487362 @default.
- W4283067187 cites W2804130304 @default.
- W4283067187 cites W2886713969 @default.
- W4283067187 cites W2910476127 @default.
- W4283067187 cites W2910804809 @default.
- W4283067187 cites W2912121921 @default.
- W4283067187 cites W2919342633 @default.
- W4283067187 cites W2941246007 @default.