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- W4283068894 abstract "The results of the MA.32 trial, examining whether metformin improved breast cancer outcomes, were published in the Journal of the American Medical Association in May 2022. 1 Goodwin P.J. Chen B.E. Gelmon K.A. et al. Effect of metformin vs placebo on invasive disease-free survival in patients with breast cancer: the MA.32 randomized clinical trial. JAMA. 2022; 327: 1963-1973 Crossref PubMed Scopus (36) Google Scholar “Common diabetes drug not effective against early-stage breast cancer, landmark trial reveals,” read the associated online news headlines. Researchers entrenched in this field have eagerly awaited the results of the MA.32 trial for over a decade. To understand whether this trial is the end of the metformin in cancer story, herein, we summarize the trial and its results, explore its place in the context of previous studies, and its future, if any, in cancer studies." @default.
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- W4283068894 date "2022-08-01" @default.
- W4283068894 modified "2023-10-14" @default.
- W4283068894 title "Metformin and Cancer: Is This the End?" @default.
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- W4283068894 doi "https://doi.org/10.1016/j.eprac.2022.06.005" @default.
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