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• W4283072249 abstract "Although microcapsules (MCs) have been used for dental resins to achieve self-healing capabilities, the fragile organic shell and single healing event functions during the service period limit their use. Herein, a novel nanoparticle-modified MC with a nano-antibacterial inorganic filler (NIF) containing a quaternary ammonium salt was synthesized to address these issues.MCs with 0 %-30 % NIFs were prepared via an in situ polymerization method and characterized their morphology, chemical composition, thermal stability, roughness, mechanical properties, and antibacterial effect. Subsequently, M-10 MCs were mixed into the resin matrix at a mass fraction of 7.5 %. The self-healing capability and cytotoxicity were evaluated.The introduction of nanomaterials enhances the shell of the MCs and endows them with an antibacterial effect. With the addition of NIFs, the roughness, modulus, and hardness values of MCs all increased (p < 0.05). The presence of M-10 MCs reduced the CFU by 2-3 orders of magnitude compared to the control group. The dental resin containing 7.5 % M-10 MCs obtained almost 69 % self-healing efficiency, without significantly compromising cell viability (p < 0.05).Self-healing MCs with NIFs were prepared for the first time with strong antibacterial properties, a substantial self-healing capability, and low toxicity. This multifunctional MC is a promising candidate for use in dental resins to extend the service life and resolve the problem of bulk fracture and secondary caries." @default.
• W4283072249 created "2022-06-19" @default.
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• W4283072249 date "2022-08-01" @default.
• W4283072249 modified "2023-10-16" @default.
• W4283072249 title "Novel nanoparticle-modified multifunctional microcapsules with self-healing and antibacterial activities for dental applications" @default.
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• W4283072249 doi "https://doi.org/10.1016/j.dental.2022.06.012" @default.
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