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- W4283072654 endingPage "1197" @default.
- W4283072654 startingPage "1188" @default.
- W4283072654 abstract "There has been significant progress in the study of extracellular vesicles (EVs) since the 2017 American Gastroenterological Association-sponsored Freston Conference Extracellular Vesicles: Biology, Translation and Clinical Application in GI Disorders. The burgeoning interest in this field stems from the increasing recognition that EVs represent an understudied form of cell-to-cell communication and contain cargo replete with biomarkers and therapeutic targets. This short review will highlight recent advances in the field, with an emphasis on colorectal cancer. After a brief introduction to secreted particles, we will describe how our laboratory became interested in EVs, which led to refined methods of isolation and identification of 2 secreted nanoparticles. We will then summarize the cargo found in small EVs released from colorectal cancer cells and other cells in the tumor microenvironment, as well as those found in the circulation of patients with colorectal cancer. Finally, we will consider the continuing challenges and future opportunities in this rapidly evolving field." @default.
- W4283072654 created "2022-06-19" @default.
- W4283072654 creator A5046249010 @default.
- W4283072654 creator A5084529927 @default.
- W4283072654 date "2022-11-01" @default.
- W4283072654 modified "2023-09-30" @default.
- W4283072654 title "Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer" @default.
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