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- W4283077988 endingPage "1964" @default.
- W4283077988 startingPage "1964" @default.
- W4283077988 abstract "The nuclear progesterone receptor (PR) is mainly known for its role as a ligand-regulated transcription factor. However, in the last ten years, this receptor's extranuclear or rapid actions have gained importance in the context of physiological and pathophysiological conditions such as cancer. The PR's polyproline (PXPP) motif allows protein-protein interaction through SH3 domains of several cytoplasmatic proteins, including the Src family kinases (SFKs). Among members of this family, cSrc is the most well-characterized protein in the scenario of rapid actions of the PR in cancer. Studies in breast cancer have provided the most detailed information on the signaling and effects triggered by the cSrc-PR interaction. Nevertheless, the study of this phenomenon and its consequences has been underestimated in other types of malignancies, especially those not associated with the reproductive system, such as glioblastomas (GBs). This review will provide a detailed analysis of the impact of the PR-cSrc interplay in the progression of some non-reproductive cancers, particularly, in GBs." @default.
- W4283077988 created "2022-06-19" @default.
- W4283077988 creator A5032459165 @default.
- W4283077988 creator A5045524171 @default.
- W4283077988 creator A5050905251 @default.
- W4283077988 date "2022-06-18" @default.
- W4283077988 modified "2023-10-17" @default.
- W4283077988 title "Rapid Actions of the Nuclear Progesterone Receptor through cSrc in Cancer" @default.
- W4283077988 cites W1569704074 @default.
- W4283077988 cites W1929023701 @default.
- W4283077988 cites W1964630747 @default.
- W4283077988 cites W1966844773 @default.
- W4283077988 cites W1967448808 @default.
- W4283077988 cites W1971130558 @default.
- W4283077988 cites W1976933694 @default.
- W4283077988 cites W1985642146 @default.
- W4283077988 cites W1986206057 @default.
- W4283077988 cites W1987889377 @default.
- W4283077988 cites W1988626741 @default.
- W4283077988 cites W1990516841 @default.
- W4283077988 cites W1994110056 @default.
- W4283077988 cites W1997562103 @default.
- W4283077988 cites W2012863911 @default.
- W4283077988 cites W2014931493 @default.
- W4283077988 cites W2015298999 @default.
- W4283077988 cites W2019318810 @default.
- W4283077988 cites W2021880374 @default.
- W4283077988 cites W2025183726 @default.
- W4283077988 cites W2025535065 @default.
- W4283077988 cites W2033161817 @default.
- W4283077988 cites W2034070845 @default.
- W4283077988 cites W2036988959 @default.
- W4283077988 cites W2038219344 @default.
- W4283077988 cites W2040762618 @default.
- W4283077988 cites W2044549752 @default.
- W4283077988 cites W2044895919 @default.
- W4283077988 cites W2047814166 @default.
- W4283077988 cites W2055310245 @default.
- W4283077988 cites W2073306537 @default.
- W4283077988 cites W2076448756 @default.
- W4283077988 cites W2078802143 @default.
- W4283077988 cites W2079930420 @default.
- W4283077988 cites W2083410333 @default.
- W4283077988 cites W2087998073 @default.
- W4283077988 cites W2093163249 @default.
- W4283077988 cites W2094890838 @default.
- W4283077988 cites W2102614641 @default.
- W4283077988 cites W2103192143 @default.
- W4283077988 cites W2108864303 @default.
- W4283077988 cites W2110321973 @default.
- W4283077988 cites W2120735426 @default.
- W4283077988 cites W2121456510 @default.
- W4283077988 cites W2129788875 @default.
- W4283077988 cites W2133108176 @default.
- W4283077988 cites W2137004572 @default.
- W4283077988 cites W2145999402 @default.
- W4283077988 cites W2148977460 @default.
- W4283077988 cites W2150900888 @default.
- W4283077988 cites W2151019365 @default.
- W4283077988 cites W2153516980 @default.
- W4283077988 cites W2164193456 @default.
- W4283077988 cites W2164557298 @default.
- W4283077988 cites W2167080732 @default.
- W4283077988 cites W2178783175 @default.
- W4283077988 cites W2281734632 @default.
- W4283077988 cites W2398979536 @default.
- W4283077988 cites W2404978977 @default.
- W4283077988 cites W2465571301 @default.
- W4283077988 cites W2513970325 @default.
- W4283077988 cites W2520883396 @default.
- W4283077988 cites W2528743173 @default.
- W4283077988 cites W2664285244 @default.
- W4283077988 cites W2735366411 @default.
- W4283077988 cites W2750589052 @default.
- W4283077988 cites W27535306 @default.
- W4283077988 cites W2885448192 @default.
- W4283077988 cites W2951450528 @default.
- W4283077988 cites W2956785853 @default.
- W4283077988 cites W2973077025 @default.
- W4283077988 cites W3033661934 @default.
- W4283077988 cites W3037038577 @default.
- W4283077988 cites W3041360673 @default.
- W4283077988 cites W3056214675 @default.
- W4283077988 cites W3118864881 @default.
- W4283077988 cites W3145816473 @default.
- W4283077988 cites W3166280230 @default.
- W4283077988 cites W3216791633 @default.
- W4283077988 cites W4200327950 @default.
- W4283077988 cites W4243804568 @default.
- W4283077988 doi "https://doi.org/10.3390/cells11121964" @default.
- W4283077988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35741094" @default.
- W4283077988 hasPublicationYear "2022" @default.
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