Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283117771> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4283117771 endingPage "3858" @default.
- W4283117771 startingPage "3855" @default.
- W4283117771 abstract "Hemophilia A is an inherited bleeding disorder characterized by a lack of plasma clotting factor VIII (FVIII). In prophylaxis or during surgery, FVIII infusions are necessary to prevent bleeding. The authors describe the perioperative challenges and application of a multidisciplinary hemostatic management approach to a Caucasian male newborn, with antenatal diagnoses of moderate hemophilia A (2 IU/dL) and dextro-transposition of the great arteries requiring arterial switch surgery within the first month of life. Because both conditions are rare, only few reports in the literature are available describing perioperative management of hemophilia in neonates and children undergoing cardiac surgery. After baseline FVIII determination and normal standard coagulation studies, iterative intravenous pharmacist-prepared plasma-derived FVIII boluses were calculated (35 IU/kg) and administered intravenously every 6 hours for 24 hours, then switched to a continuous infusion and guided by daily chromogenic clotting FVIII activity assay for targeted values between 80 and 100 IU/dL. Successful cardiac surgery, using cardiopulmonary bypass, was performed with continuous infusion of FVIII at 5 IU/kg/h. Thirteen days after surgery, the FVIII antibody screening remained negative and continuous infusion was switched in favor of a daily intravenous bolus treatment to facilitate reconciliation to the center of origin. The authors' multidisciplinary strategy, established antenatally, allowed for successful care in this highly complex and rare situation." @default.
- W4283117771 created "2022-06-20" @default.
- W4283117771 creator A5044687073 @default.
- W4283117771 creator A5052748294 @default.
- W4283117771 creator A5065126452 @default.
- W4283117771 creator A5070315809 @default.
- W4283117771 creator A5078788587 @default.
- W4283117771 creator A5086015762 @default.
- W4283117771 date "2022-10-01" @default.
- W4283117771 modified "2023-10-11" @default.
- W4283117771 title "Perioperative Hemostatic Management of a Newborn With Hereditary Hemophilia A Undergoing Emergent Surgery for Dextro-Transposition of the Great Arteries" @default.
- W4283117771 cites W1523598805 @default.
- W4283117771 cites W1914447692 @default.
- W4283117771 cites W1999038512 @default.
- W4283117771 cites W2083702593 @default.
- W4283117771 cites W2164475789 @default.
- W4283117771 cites W2274569134 @default.
- W4283117771 cites W2496964971 @default.
- W4283117771 cites W2579338563 @default.
- W4283117771 cites W3022597690 @default.
- W4283117771 cites W3037023937 @default.
- W4283117771 cites W3037598620 @default.
- W4283117771 cites W3047046471 @default.
- W4283117771 cites W3087813589 @default.
- W4283117771 doi "https://doi.org/10.1053/j.jvca.2022.06.018" @default.
- W4283117771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35879147" @default.
- W4283117771 hasPublicationYear "2022" @default.
- W4283117771 type Work @default.
- W4283117771 citedByCount "1" @default.
- W4283117771 countsByYear W42831177712022 @default.
- W4283117771 crossrefType "journal-article" @default.
- W4283117771 hasAuthorship W4283117771A5044687073 @default.
- W4283117771 hasAuthorship W4283117771A5052748294 @default.
- W4283117771 hasAuthorship W4283117771A5065126452 @default.
- W4283117771 hasAuthorship W4283117771A5070315809 @default.
- W4283117771 hasAuthorship W4283117771A5078788587 @default.
- W4283117771 hasAuthorship W4283117771A5086015762 @default.
- W4283117771 hasBestOaLocation W42831177711 @default.
- W4283117771 hasConcept C126322002 @default.
- W4283117771 hasConcept C141071460 @default.
- W4283117771 hasConcept C164705383 @default.
- W4283117771 hasConcept C2776064143 @default.
- W4283117771 hasConcept C2777987278 @default.
- W4283117771 hasConcept C2778589496 @default.
- W4283117771 hasConcept C2778881276 @default.
- W4283117771 hasConcept C2778961111 @default.
- W4283117771 hasConcept C2779234561 @default.
- W4283117771 hasConcept C2780074459 @default.
- W4283117771 hasConcept C2780868729 @default.
- W4283117771 hasConcept C2992139802 @default.
- W4283117771 hasConcept C31174226 @default.
- W4283117771 hasConcept C42219234 @default.
- W4283117771 hasConcept C43376680 @default.
- W4283117771 hasConcept C536800656 @default.
- W4283117771 hasConcept C54355233 @default.
- W4283117771 hasConcept C71924100 @default.
- W4283117771 hasConcept C86803240 @default.
- W4283117771 hasConceptScore W4283117771C126322002 @default.
- W4283117771 hasConceptScore W4283117771C141071460 @default.
- W4283117771 hasConceptScore W4283117771C164705383 @default.
- W4283117771 hasConceptScore W4283117771C2776064143 @default.
- W4283117771 hasConceptScore W4283117771C2777987278 @default.
- W4283117771 hasConceptScore W4283117771C2778589496 @default.
- W4283117771 hasConceptScore W4283117771C2778881276 @default.
- W4283117771 hasConceptScore W4283117771C2778961111 @default.
- W4283117771 hasConceptScore W4283117771C2779234561 @default.
- W4283117771 hasConceptScore W4283117771C2780074459 @default.
- W4283117771 hasConceptScore W4283117771C2780868729 @default.
- W4283117771 hasConceptScore W4283117771C2992139802 @default.
- W4283117771 hasConceptScore W4283117771C31174226 @default.
- W4283117771 hasConceptScore W4283117771C42219234 @default.
- W4283117771 hasConceptScore W4283117771C43376680 @default.
- W4283117771 hasConceptScore W4283117771C536800656 @default.
- W4283117771 hasConceptScore W4283117771C54355233 @default.
- W4283117771 hasConceptScore W4283117771C71924100 @default.
- W4283117771 hasConceptScore W4283117771C86803240 @default.
- W4283117771 hasFunder F4320323878 @default.
- W4283117771 hasIssue "10" @default.
- W4283117771 hasLocation W42831177711 @default.
- W4283117771 hasLocation W42831177712 @default.
- W4283117771 hasOpenAccess W4283117771 @default.
- W4283117771 hasPrimaryLocation W42831177711 @default.
- W4283117771 hasRelatedWork W2010168993 @default.
- W4283117771 hasRelatedWork W2041356216 @default.
- W4283117771 hasRelatedWork W2047769455 @default.
- W4283117771 hasRelatedWork W2057646315 @default.
- W4283117771 hasRelatedWork W2359239460 @default.
- W4283117771 hasRelatedWork W2577425961 @default.
- W4283117771 hasRelatedWork W2902754020 @default.
- W4283117771 hasRelatedWork W3110839361 @default.
- W4283117771 hasRelatedWork W4283117771 @default.
- W4283117771 hasRelatedWork W2524566684 @default.
- W4283117771 hasVolume "36" @default.
- W4283117771 isParatext "false" @default.
- W4283117771 isRetracted "false" @default.
- W4283117771 workType "article" @default.