Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283120925> ?p ?o ?g. }
- W4283120925 endingPage "3911" @default.
- W4283120925 startingPage "3911" @default.
- W4283120925 abstract "Acute myeloid leukemia (AML) accounts for approximately 15-20% of all childhood leukemia cases. The overall survival of children with acute myeloid leukemia does not exceed 82%, and the 5-year event-free survival rates range from 46% to 69%. Such suboptimal outcomes are the result of numerous mutations and epigenetic changes occurring in this disease that adversely affect the susceptibility to treatment and relapse rate. We describe various molecular-targeted therapies that have been developed in recent years to meet these challenges and were or are currently being studied in clinical trials. First introduced in adult AML, novel forms of treatment are slowly beginning to change the therapeutic approach to pediatric AML. Despite promising results of clinical trials investigating new drugs, further clinical studies involving greater numbers of pediatric patients are still needed to improve the outcomes in childhood AML." @default.
- W4283120925 created "2022-06-20" @default.
- W4283120925 creator A5003160827 @default.
- W4283120925 creator A5015948254 @default.
- W4283120925 creator A5020704806 @default.
- W4283120925 creator A5030870747 @default.
- W4283120925 creator A5052965523 @default.
- W4283120925 creator A5088081483 @default.
- W4283120925 date "2022-06-18" @default.
- W4283120925 modified "2023-10-16" @default.
- W4283120925 title "Molecular-Targeted Therapy of Pediatric Acute Myeloid Leukemia" @default.
- W4283120925 cites W2018591383 @default.
- W4283120925 cites W2021663709 @default.
- W4283120925 cites W2045525494 @default.
- W4283120925 cites W2118250079 @default.
- W4283120925 cites W2124513722 @default.
- W4283120925 cites W2128919238 @default.
- W4283120925 cites W2155281787 @default.
- W4283120925 cites W2158022600 @default.
- W4283120925 cites W2169923083 @default.
- W4283120925 cites W2317674375 @default.
- W4283120925 cites W2715749014 @default.
- W4283120925 cites W2795150236 @default.
- W4283120925 cites W2800912743 @default.
- W4283120925 cites W2805862637 @default.
- W4283120925 cites W2810896718 @default.
- W4283120925 cites W2886748809 @default.
- W4283120925 cites W2892036979 @default.
- W4283120925 cites W2896388611 @default.
- W4283120925 cites W2899678905 @default.
- W4283120925 cites W2899818119 @default.
- W4283120925 cites W2902725436 @default.
- W4283120925 cites W2912499134 @default.
- W4283120925 cites W2922692686 @default.
- W4283120925 cites W2953623020 @default.
- W4283120925 cites W2955461553 @default.
- W4283120925 cites W2966307898 @default.
- W4283120925 cites W2980712409 @default.
- W4283120925 cites W2982353618 @default.
- W4283120925 cites W2984496473 @default.
- W4283120925 cites W2985088562 @default.
- W4283120925 cites W2995587299 @default.
- W4283120925 cites W2996445903 @default.
- W4283120925 cites W2998127786 @default.
- W4283120925 cites W3004873674 @default.
- W4283120925 cites W3007934784 @default.
- W4283120925 cites W3013447738 @default.
- W4283120925 cites W3024552410 @default.
- W4283120925 cites W3026833064 @default.
- W4283120925 cites W3031071120 @default.
- W4283120925 cites W3033706053 @default.
- W4283120925 cites W3033939453 @default.
- W4283120925 cites W3046395109 @default.
- W4283120925 cites W3057865763 @default.
- W4283120925 cites W3087497958 @default.
- W4283120925 cites W3092073603 @default.
- W4283120925 cites W3093149563 @default.
- W4283120925 cites W3094712772 @default.
- W4283120925 cites W3095158319 @default.
- W4283120925 cites W3099682853 @default.
- W4283120925 cites W3113353020 @default.
- W4283120925 cites W3114952208 @default.
- W4283120925 cites W3118498465 @default.
- W4283120925 cites W3120640518 @default.
- W4283120925 cites W3129701356 @default.
- W4283120925 cites W3131786547 @default.
- W4283120925 cites W3138300258 @default.
- W4283120925 cites W3153673991 @default.
- W4283120925 cites W3157351142 @default.
- W4283120925 cites W3159502909 @default.
- W4283120925 cites W3160345870 @default.
- W4283120925 cites W3164835888 @default.
- W4283120925 cites W3164974595 @default.
- W4283120925 cites W3165390856 @default.
- W4283120925 cites W3171257991 @default.
- W4283120925 cites W3184041689 @default.
- W4283120925 cites W3184794666 @default.
- W4283120925 cites W3194543059 @default.
- W4283120925 cites W3196087121 @default.
- W4283120925 cites W3196899418 @default.
- W4283120925 cites W3198249741 @default.
- W4283120925 cites W3203859548 @default.
- W4283120925 cites W4205268423 @default.
- W4283120925 cites W4212912425 @default.
- W4283120925 cites W4213144975 @default.
- W4283120925 cites W4224312859 @default.
- W4283120925 cites W4226191928 @default.
- W4283120925 doi "https://doi.org/10.3390/molecules27123911" @default.
- W4283120925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35745032" @default.
- W4283120925 hasPublicationYear "2022" @default.
- W4283120925 type Work @default.
- W4283120925 citedByCount "2" @default.
- W4283120925 countsByYear W42831209252023 @default.
- W4283120925 crossrefType "journal-article" @default.
- W4283120925 hasAuthorship W4283120925A5003160827 @default.
- W4283120925 hasAuthorship W4283120925A5015948254 @default.
- W4283120925 hasAuthorship W4283120925A5020704806 @default.
- W4283120925 hasAuthorship W4283120925A5030870747 @default.