Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283162335> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4283162335 endingPage "177" @default.
- W4283162335 startingPage "168" @default.
- W4283162335 abstract "This study evaluated the sedative, and anticonvulsant activities of the aqueous (AESM) and ethanol (EESM) dried leaf extracts of Solenostemon monostachyus. The sedative effect of the extracts was evaluated with ketamine-induced hypnosis (100 mg/kg, i.p.). Also, the anticonvulsant activity was evaluated using pentylenetetrazole (PTZ)-induced convulsion (85 mg/kg, i.p.), strychnine-induced convulsion (2 mg/kg, i.p.) and maximal electroshock (MES)-induced convulsion models. The AESM (200 mg/kg, p.o.) gave 66.67% protection, while EESM (800 mg/kg, p.o.) gave 100% protection against the hind limb tonic extension on the MES. The AESM only at 200 mg/kg, p.o. caused a significant change (p < 0.01) in the convulsion latency and time of death in PTZ –induced convulsion. The AESM and EESM (200, 400 and 800 mg/kg, p.o.) significantly (p < 0.05 – 0.01) shortened sleep latency. At 400 and 800 mg/kg, p.o., AESM prolonged (p < 0.05) total sleeping time while EESM at 800 mg/kg, p.o. significantly (p < 0.05) prolonged total sleeping time relative to vehicle. The study concluded that the aqueous leaf and ethanol dried leaf extracts of S. monostachyus possessed sedative and mild anticonvulsant activities." @default.
- W4283162335 created "2022-06-21" @default.
- W4283162335 creator A5003795064 @default.
- W4283162335 creator A5059797031 @default.
- W4283162335 date "2022-06-30" @default.
- W4283162335 modified "2023-09-27" @default.
- W4283162335 title "Sedative and anticonvulsant activities of aqueous and ethanol dried leaf extracts of Solenostemon monostachyus in mice" @default.
- W4283162335 doi "https://doi.org/10.30574/gscbps.2022.19.3.0221" @default.
- W4283162335 hasPublicationYear "2022" @default.
- W4283162335 type Work @default.
- W4283162335 citedByCount "0" @default.
- W4283162335 crossrefType "journal-article" @default.
- W4283162335 hasAuthorship W4283162335A5003795064 @default.
- W4283162335 hasAuthorship W4283162335A5059797031 @default.
- W4283162335 hasBestOaLocation W42831623351 @default.
- W4283162335 hasConcept C118552586 @default.
- W4283162335 hasConcept C185592680 @default.
- W4283162335 hasConcept C2775858608 @default.
- W4283162335 hasConcept C2777010014 @default.
- W4283162335 hasConcept C2777602617 @default.
- W4283162335 hasConcept C2777725853 @default.
- W4283162335 hasConcept C2778186239 @default.
- W4283162335 hasConcept C2780161600 @default.
- W4283162335 hasConcept C42219234 @default.
- W4283162335 hasConcept C55493867 @default.
- W4283162335 hasConcept C71924100 @default.
- W4283162335 hasConcept C98274493 @default.
- W4283162335 hasConceptScore W4283162335C118552586 @default.
- W4283162335 hasConceptScore W4283162335C185592680 @default.
- W4283162335 hasConceptScore W4283162335C2775858608 @default.
- W4283162335 hasConceptScore W4283162335C2777010014 @default.
- W4283162335 hasConceptScore W4283162335C2777602617 @default.
- W4283162335 hasConceptScore W4283162335C2777725853 @default.
- W4283162335 hasConceptScore W4283162335C2778186239 @default.
- W4283162335 hasConceptScore W4283162335C2780161600 @default.
- W4283162335 hasConceptScore W4283162335C42219234 @default.
- W4283162335 hasConceptScore W4283162335C55493867 @default.
- W4283162335 hasConceptScore W4283162335C71924100 @default.
- W4283162335 hasConceptScore W4283162335C98274493 @default.
- W4283162335 hasIssue "3" @default.
- W4283162335 hasLocation W42831623351 @default.
- W4283162335 hasLocation W42831623352 @default.
- W4283162335 hasOpenAccess W4283162335 @default.
- W4283162335 hasPrimaryLocation W42831623351 @default.
- W4283162335 hasRelatedWork W1977753240 @default.
- W4283162335 hasRelatedWork W2032236869 @default.
- W4283162335 hasRelatedWork W2078940034 @default.
- W4283162335 hasRelatedWork W2153134881 @default.
- W4283162335 hasRelatedWork W2181386121 @default.
- W4283162335 hasRelatedWork W2402552335 @default.
- W4283162335 hasRelatedWork W2736917669 @default.
- W4283162335 hasRelatedWork W2921289179 @default.
- W4283162335 hasRelatedWork W4283162335 @default.
- W4283162335 hasRelatedWork W2174961586 @default.
- W4283162335 hasVolume "19" @default.
- W4283162335 isParatext "false" @default.
- W4283162335 isRetracted "false" @default.
- W4283162335 workType "article" @default.