Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283165909> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4283165909 endingPage "A424" @default.
- W4283165909 startingPage "A424" @default.
- W4283165909 abstract "TYPE: Case Report TOPIC: Pulmonary Manifestations of Systemic Disease INTRODUCTION: Sarcoidosis is a chronic multisystemic disease characterized by noncaseating granulomas which affects the pulmonary system and intrathoracic lymph nodes most frequently. Pleural and renal involvement in sarcoidosis is rare. CASE PRESENTATION: A 34 year old African American female with presented with progressively worsening shortness of breath. Of note, this was her fourth hospitalization in six months. Her first presentation was for flank pain. Workup revealed a renal infiltrative process and a left sided pleural effusion. Kidney biopsy was significant for noncaseating granulomas. A right lower lobe pulmonary embolus (PE) was diagnosed on her second admission and recurrent left sided pleural effusions were noted on the third and fourth admissions. Hepatic infiltrative hypodensities in the liver were visualized. Angiotensin converting enzyme level was 137 U/L. On her final presentation, bronchoscopy demonstrated a stereotypical cobblestone appearance and transbronchial lymph node biopsy demonstrated non-necrotizing granulomatous disease. DISCUSSION: Most cases of sarcoidosis tend to affect the lungs, however, both pleural effusion or granulomatous interstitial nephritis (GIN) as a presenting symptom of the disease is uncommon. Pleural involvement is sarcoidosis occurs in 0.7-10%. Clinically relevant GIN is identified in 0.5-0.9% of native kidney biopsies making it a rare histological diagnosis. With workup for other pathology being negative, sarcoidosis was assessed as the cause for the unique clinical course of this patient with biopsy proven pleural and renal disease, and possible hematologic, ocular, and hepatic involvement. CONCLUSIONS: Clinicians must maintain a high level of suspicion for sarcoidosis in patients with multisystemic disease, due to the potential for atypical presentations. DISCLOSURE: Nothing to declare. KEYWORD: Sarcoidosis" @default.
- W4283165909 created "2022-06-21" @default.
- W4283165909 creator A5000111628 @default.
- W4283165909 creator A5003450329 @default.
- W4283165909 creator A5008746398 @default.
- W4283165909 creator A5039314383 @default.
- W4283165909 creator A5054450018 @default.
- W4283165909 creator A5060390295 @default.
- W4283165909 creator A5060598529 @default.
- W4283165909 date "2022-06-01" @default.
- W4283165909 modified "2023-09-25" @default.
- W4283165909 title "MULTISYSTEMIC SARCOIDOSIS: AN UNUSUAL PRESENTATION" @default.
- W4283165909 doi "https://doi.org/10.1016/j.chest.2021.12.454" @default.
- W4283165909 hasPublicationYear "2022" @default.
- W4283165909 type Work @default.
- W4283165909 citedByCount "0" @default.
- W4283165909 crossrefType "journal-article" @default.
- W4283165909 hasAuthorship W4283165909A5000111628 @default.
- W4283165909 hasAuthorship W4283165909A5003450329 @default.
- W4283165909 hasAuthorship W4283165909A5008746398 @default.
- W4283165909 hasAuthorship W4283165909A5039314383 @default.
- W4283165909 hasAuthorship W4283165909A5054450018 @default.
- W4283165909 hasAuthorship W4283165909A5060390295 @default.
- W4283165909 hasAuthorship W4283165909A5060598529 @default.
- W4283165909 hasBestOaLocation W42831659091 @default.
- W4283165909 hasConcept C126322002 @default.
- W4283165909 hasConcept C126838900 @default.
- W4283165909 hasConcept C141071460 @default.
- W4283165909 hasConcept C142724271 @default.
- W4283165909 hasConcept C2775934546 @default.
- W4283165909 hasConcept C2776178081 @default.
- W4283165909 hasConcept C2776517811 @default.
- W4283165909 hasConcept C2777714996 @default.
- W4283165909 hasConcept C2778653478 @default.
- W4283165909 hasConcept C2778704086 @default.
- W4283165909 hasConcept C2779634585 @default.
- W4283165909 hasConcept C2781301800 @default.
- W4283165909 hasConcept C71924100 @default.
- W4283165909 hasConceptScore W4283165909C126322002 @default.
- W4283165909 hasConceptScore W4283165909C126838900 @default.
- W4283165909 hasConceptScore W4283165909C141071460 @default.
- W4283165909 hasConceptScore W4283165909C142724271 @default.
- W4283165909 hasConceptScore W4283165909C2775934546 @default.
- W4283165909 hasConceptScore W4283165909C2776178081 @default.
- W4283165909 hasConceptScore W4283165909C2776517811 @default.
- W4283165909 hasConceptScore W4283165909C2777714996 @default.
- W4283165909 hasConceptScore W4283165909C2778653478 @default.
- W4283165909 hasConceptScore W4283165909C2778704086 @default.
- W4283165909 hasConceptScore W4283165909C2779634585 @default.
- W4283165909 hasConceptScore W4283165909C2781301800 @default.
- W4283165909 hasConceptScore W4283165909C71924100 @default.
- W4283165909 hasIssue "6" @default.
- W4283165909 hasLocation W42831659091 @default.
- W4283165909 hasOpenAccess W4283165909 @default.
- W4283165909 hasPrimaryLocation W42831659091 @default.
- W4283165909 hasRelatedWork W1841185769 @default.
- W4283165909 hasRelatedWork W2072782418 @default.
- W4283165909 hasRelatedWork W2424719165 @default.
- W4283165909 hasRelatedWork W2461300391 @default.
- W4283165909 hasRelatedWork W2578804357 @default.
- W4283165909 hasRelatedWork W2777641147 @default.
- W4283165909 hasRelatedWork W3022445673 @default.
- W4283165909 hasRelatedWork W343843269 @default.
- W4283165909 hasRelatedWork W4243592654 @default.
- W4283165909 hasRelatedWork W2189760951 @default.
- W4283165909 hasVolume "161" @default.
- W4283165909 isParatext "false" @default.
- W4283165909 isRetracted "false" @default.
- W4283165909 workType "article" @default.