FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283167249> ?p ?o ?g. }

• W4283167249 abstract "Myocarditis is an inflammatory disease of the myocardium with focal or diffuse involvement. Viral infections are the most common cause of myocarditis, especially in Western countries. A recent viral illness with gastroenteric or upper respiratory symptoms often precedes myocarditis. The absence of specific pathognomonic features in conjunction with the wide spectrum of clinical manifestations that range from subclinical cases to sudden cardiac death (SCD) makes myocarditis diagnosis particularly challenging. Moreover, myocarditis might represent a cause of initially unexplained dilated cardiomyopathy (DCM) and heart failure (HF), especially among children and young adults. Cardiac magnetic resonance imaging (CMR) is crucial for myocarditis diagnosis, because of its ability to detect interstitial edema during acute inflammation. Assessment of subepicardial or mid-myocardial fibrosis by late gadolinium enhancement (LGE) is typical for myocarditis. Cardiac arrhythmias are frequent events that may arise especially in more severe myocarditis cases. The most common form of arrhythmia is atrial fibrillation, followed by ventricular tachycardia. Documented arrhythmias have been reported more commonly with HIV myocarditis than other more common infections such as Adenovirus, Parvovirus B19, human Herpes virus 6, and Enterovirus. The mechanisms of arrhythmogenesis in myocardial inflammation are not fully understood; in the acute phase, the spectrum of arrhythmogenesis ranges from a direct effect on cardiomyocytes that leads to electrical instability and ion channel impairment to ischemia from coronary macro- or microvascular disease. In chronic myocarditis, instead, myocardial replacement with fibrosis promotes scar-mediated re-entrant ventricular arrhythmias. Observational data suggested the important role of CMR, with LGE being the strongest independent predictor of SCD, cardiac, and all-cause mortality. In acute myocarditis, the most common localization of subepicardial LGE dwells in the lateral wall. Patients with myocarditis that develop HF and arrhythmias usually show a larger LGE distribution involving several myocardial segments. Moreover, a mid-layer LGE in the interventricular septum is more frequent in acute myocarditis than in acute coronary syndromes cases. The risk of SCD in patients with wide areas of LGE is significant, and a shared decision-making approach is warranted. Nevertheless, there is no formal consensus about the extension of LGE to justify implantable cardioverter defibrillator (ICD) implantation in primary prevention." @default.
• W4283167249 created "2022-06-21" @default.
• W4283167249 creator A5013408510 @default.
• W4283167249 creator A5030176430 @default.
• W4283167249 creator A5039838097 @default.
• W4283167249 creator A5042564588 @default.
• W4283167249 creator A5066606481 @default.
• W4283167249 creator A5072191074 @default.
• W4283167249 creator A5084488199 @default.
• W4283167249 creator A5089192698 @default.
• W4283167249 date "2022-06-20" @default.
• W4283167249 modified "2023-10-05" @default.
• W4283167249 title "Viral Myocarditis: Classification, Diagnosis, and Clinical Implications" @default.
• W4283167249 cites W1489130191 @default.
• W4283167249 cites W1710720572 @default.
• W4283167249 cites W1966836886 @default.
• W4283167249 cites W1970735226 @default.
• W4283167249 cites W1978453160 @default.
• W4283167249 cites W1987413931 @default.
• W4283167249 cites W1993427319 @default.
• W4283167249 cites W1996110848 @default.
• W4283167249 cites W2010909136 @default.
• W4283167249 cites W2015417695 @default.
• W4283167249 cites W2015708271 @default.
• W4283167249 cites W2020982142 @default.
• W4283167249 cites W2028257769 @default.
• W4283167249 cites W2029971767 @default.
• W4283167249 cites W2041818415 @default.
• W4283167249 cites W2050406436 @default.
• W4283167249 cites W2062999914 @default.
• W4283167249 cites W2068625452 @default.
• W4283167249 cites W2070422406 @default.
• W4283167249 cites W2075754547 @default.
• W4283167249 cites W2077566335 @default.
• W4283167249 cites W2091134353 @default.
• W4283167249 cites W2097087273 @default.
• W4283167249 cites W2106387371 @default.
• W4283167249 cites W2112667125 @default.
• W4283167249 cites W2119975602 @default.
• W4283167249 cites W2121889641 @default.
• W4283167249 cites W2124191742 @default.
• W4283167249 cites W2125958520 @default.
• W4283167249 cites W2126824733 @default.
• W4283167249 cites W2135932484 @default.
• W4283167249 cites W2136260361 @default.
• W4283167249 cites W2137937248 @default.
• W4283167249 cites W2140921081 @default.
• W4283167249 cites W2146861064 @default.
• W4283167249 cites W2156173622 @default.
• W4283167249 cites W2178481119 @default.
• W4283167249 cites W2285375100 @default.
• W4283167249 cites W2302036983 @default.
• W4283167249 cites W2333914885 @default.
• W4283167249 cites W2342191844 @default.
• W4283167249 cites W2420424132 @default.
• W4283167249 cites W2548775624 @default.
• W4283167249 cites W2599761051 @default.
• W4283167249 cites W2618452547 @default.
• W4283167249 cites W2755321542 @default.
• W4283167249 cites W2761284841 @default.
• W4283167249 cites W2762343916 @default.
• W4283167249 cites W2766742462 @default.
• W4283167249 cites W2776080230 @default.
• W4283167249 cites W2791051699 @default.
• W4283167249 cites W2803674135 @default.
• W4283167249 cites W2885426228 @default.
• W4283167249 cites W2887314940 @default.
• W4283167249 cites W2899332711 @default.
• W4283167249 cites W2900277959 @default.
• W4283167249 cites W2901170595 @default.
• W4283167249 cites W2903720062 @default.
• W4283167249 cites W2903759577 @default.
• W4283167249 cites W2924372855 @default.
• W4283167249 cites W2945360683 @default.
• W4283167249 cites W2968334567 @default.
• W4283167249 cites W2972235069 @default.
• W4283167249 cites W2982948468 @default.
• W4283167249 cites W2988186555 @default.
• W4283167249 cites W3007817453 @default.
• W4283167249 cites W3010077348 @default.
• W4283167249 cites W3011921565 @default.
• W4283167249 cites W3012421327 @default.
• W4283167249 cites W3012747666 @default.
• W4283167249 cites W3015834895 @default.
• W4283167249 cites W3015992717 @default.
• W4283167249 cites W3021123404 @default.
• W4283167249 cites W3034667454 @default.
• W4283167249 cites W3035314471 @default.
• W4283167249 cites W3037553266 @default.
• W4283167249 cites W3043529892 @default.
• W4283167249 cites W3045277594 @default.
• W4283167249 cites W3092140279 @default.
• W4283167249 cites W3092415006 @default.
• W4283167249 cites W3094217429 @default.
• W4283167249 cites W3103940138 @default.
• W4283167249 cites W3119094176 @default.
• W4283167249 cites W3138672440 @default.
• W4283167249 cites W3156546374 @default.
• W4283167249 cites W3159522339 @default.
• W4283167249 cites W3176305688 @default.

• next