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- W4283168064 abstract "The paper investigates the efficiency of phage-nano combinational therapy in treating planktonic and biofilm bacteria. Silver nanoparticles (AgNPs) were synthesized by olive oil as a coating emulation and characterized. Then, the antibacterial activity, biofilm inhibition, and the compatibility of phage ZCEC5 with AgNPs were evaluated. The results revealed that AgNPs were effective against a wide range of bacteria including Enterobacter spp., Listeria monocytogenes, Klebsiella pneumoniae, Salmonella Enteritidis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus sciuri, with a minimum inhibitory concentration (MIC) ranging from 0.6 to 3.15% and a minimum bactericidal concentration (MBC) ranged from 3.15 to 12.5%. As a model bacteria, E. coli O157:H7 was tested against the formulated AgNPs alone, and in combination with bacteriophage ZCEC5. While the MIC and MBC for E. coli treated with the AgNPs only were 1.1% and 3.15%, respectively, when combined with phage ZCEC5 (∼108 PFU/mL), the MIC and MBC were reduced to be 0.13% and 0.25%, respectively. Therefore, this paperwork introduces an antibacterial AgNPs against a wide spectrum of Gram-positive and Gram-negative bacteria, along with a novel combinational therapy of AgNPs and bacteriophage." @default.
- W4283168064 created "2022-06-21" @default.
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- W4283168064 date "2022-06-19" @default.
- W4283168064 modified "2023-09-29" @default.
- W4283168064 title "The antibacterial and biofilm inhibition activity of encapsulated silver nanoparticles in emulsions and its synergistic effect with <i>E. coli</i> bacteriophage" @default.
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- W4283168064 doi "https://doi.org/10.1080/24701556.2022.2081191" @default.
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