FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283169626> ?p ?o ?g. }

• W4283169626 endingPage "120367" @default.
• W4283169626 startingPage "120367" @default.
• W4283169626 abstract "Losses associated with forest pest outbreaks are increasing at an alarming rate, exacerbated by fluctuating climate patterns, and unimpeded by traditional management approaches that fail to keep pace with growing pressures. Future forest pest management strategies demand augmentation with next generation approaches. RNA interference, or RNAi, is a naturally occurring eukaryotic immune response to viral infection that works by disrupting the translation of mRNA into protein and can be manipulated to cause insect mortality through the introduction of carefully designed dsRNAs. The effective induction of the RNAi pathway depends on the exact match of a sequence at least sixteen nucleotides in length, making non-target effects unlikely. Thus, RNAi is increasingly praised as a species-specific pest management approach. The southern pine beetle (SPB), Dendroctonus frontalis, and its congener, the mountain pine beetle (MPB), D. ponderosae, are highly destructive forest pests endemic to North and Central America experiencing unprecedented range expansions, with extensive impacts on affected ecosystems. We have demonstrated that oral ingestion of specific dsRNAs induces gene silencing via RNAi and causes rapid and significant mortality in both SPB and MPB. Here we evaluate the ability of dsRNAs targeting SPB to affect gene expression in MPB, and the ability of dsRNAs targeting MPB to affect gene expression in SPB. We found that species-specific dsRNAs designed for gene silencing in one species can silence genes in the reciprocal species, offering the potential for development of RNAi as a Dendroctonus-specific management tool against rapidly expanding bark beetle populations." @default.
• W4283169626 created "2022-06-21" @default.
• W4283169626 creator A5033803602 @default.
• W4283169626 creator A5058040351 @default.
• W4283169626 date "2022-09-01" @default.
• W4283169626 modified "2023-10-02" @default.
• W4283169626 title "Using RNAi to silence heat shock protein has congeneric effects in North America’s Dendroctonus bark beetles" @default.
• W4283169626 cites W1599347333 @default.
• W4283169626 cites W1967167182 @default.
• W4283169626 cites W1978290762 @default.
• W4283169626 cites W2001025029 @default.
• W4283169626 cites W2029604816 @default.
• W4283169626 cites W2030239671 @default.
• W4283169626 cites W2034046707 @default.
• W4283169626 cites W2043082756 @default.
• W4283169626 cites W2044471898 @default.
• W4283169626 cites W2045172148 @default.
• W4283169626 cites W2052283076 @default.
• W4283169626 cites W2054363760 @default.
• W4283169626 cites W2060340560 @default.
• W4283169626 cites W2081994757 @default.
• W4283169626 cites W2101142978 @default.
• W4283169626 cites W2107277218 @default.
• W4283169626 cites W2112221933 @default.
• W4283169626 cites W2120311182 @default.
• W4283169626 cites W2120545471 @default.
• W4283169626 cites W2121440246 @default.
• W4283169626 cites W2122335343 @default.
• W4283169626 cites W2128412621 @default.
• W4283169626 cites W2178336871 @default.
• W4283169626 cites W2463332732 @default.
• W4283169626 cites W2466633265 @default.
• W4283169626 cites W2479428700 @default.
• W4283169626 cites W2497617974 @default.
• W4283169626 cites W2554569574 @default.
• W4283169626 cites W2594763727 @default.
• W4283169626 cites W2610492596 @default.
• W4283169626 cites W2747007516 @default.
• W4283169626 cites W2757953848 @default.
• W4283169626 cites W2769030298 @default.
• W4283169626 cites W2800000101 @default.
• W4283169626 cites W2804307132 @default.
• W4283169626 cites W2905849725 @default.
• W4283169626 cites W2906191605 @default.
• W4283169626 cites W2933752725 @default.
• W4283169626 cites W2938574745 @default.
• W4283169626 cites W3004191854 @default.
• W4283169626 cites W3016306046 @default.
• W4283169626 cites W3037074028 @default.
• W4283169626 cites W3119263865 @default.
• W4283169626 cites W3209727439 @default.
• W4283169626 cites W4200174395 @default.
• W4283169626 cites W4251060592 @default.
• W4283169626 doi "https://doi.org/10.1016/j.foreco.2022.120367" @default.
• W4283169626 hasPublicationYear "2022" @default.
• W4283169626 type Work @default.
• W4283169626 citedByCount "1" @default.
• W4283169626 countsByYear W42831696262023 @default.
• W4283169626 crossrefType "journal-article" @default.
• W4283169626 hasAuthorship W4283169626A5033803602 @default.
• W4283169626 hasAuthorship W4283169626A5058040351 @default.
• W4283169626 hasConcept C104317684 @default.
• W4283169626 hasConcept C119056186 @default.
• W4283169626 hasConcept C166703698 @default.
• W4283169626 hasConcept C18903297 @default.
• W4283169626 hasConcept C2777131384 @default.
• W4283169626 hasConcept C2778683101 @default.
• W4283169626 hasConcept C2779030997 @default.
• W4283169626 hasConcept C2779751432 @default.
• W4283169626 hasConcept C54355233 @default.
• W4283169626 hasConcept C67705224 @default.
• W4283169626 hasConcept C86803240 @default.
• W4283169626 hasConceptScore W4283169626C104317684 @default.
• W4283169626 hasConceptScore W4283169626C119056186 @default.
• W4283169626 hasConceptScore W4283169626C166703698 @default.
• W4283169626 hasConceptScore W4283169626C18903297 @default.
• W4283169626 hasConceptScore W4283169626C2777131384 @default.
• W4283169626 hasConceptScore W4283169626C2778683101 @default.
• W4283169626 hasConceptScore W4283169626C2779030997 @default.
• W4283169626 hasConceptScore W4283169626C2779751432 @default.
• W4283169626 hasConceptScore W4283169626C54355233 @default.
• W4283169626 hasConceptScore W4283169626C67705224 @default.
• W4283169626 hasConceptScore W4283169626C86803240 @default.
• W4283169626 hasLocation W42831696261 @default.
• W4283169626 hasOpenAccess W4283169626 @default.
• W4283169626 hasPrimaryLocation W42831696261 @default.
• W4283169626 hasRelatedWork W1887613416 @default.
• W4283169626 hasRelatedWork W1964004334 @default.
• W4283169626 hasRelatedWork W2175404876 @default.
• W4283169626 hasRelatedWork W2608920092 @default.
• W4283169626 hasRelatedWork W2617121102 @default.
• W4283169626 hasRelatedWork W3037074028 @default.
• W4283169626 hasRelatedWork W4283169626 @default.
• W4283169626 hasRelatedWork W620904634 @default.
• W4283169626 hasRelatedWork W798680410 @default.
• W4283169626 hasRelatedWork W1033163757 @default.
• W4283169626 hasVolume "520" @default.
• W4283169626 isParatext "false" @default.

• next