FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283207415> ?p ?o ?g. }

• W4283207415 abstract "Recent studies reported that folate supplementation has beneficial effects on major depression. The Methylenetetrahydrofolate reductase (MTHFR) enzyme is crucial in folate metabolism. This population-based study examined the association between MTHFR rs17367504 polymorphism and major depressive disorder based on exercise habits.Taiwan Biobank (TWB) provided demographic and genotype data between 2008 and 2015. The biobank participants were Taiwanese aged 30 to 70. Data on major depressive disorder (MDD) were obtained from the National Health Insurance Research Database (NHIRD).A total of 636 individuals were identified with MDD, whereas 17,298 individuals were considered controls. The associations of MTHFR rs17367504 and exercise with MDD risk were estimated using logistic regression models. The distribution of MTHFR rs17367504 genotype frequencies differed significantly between the MDD and control groups. We found that, compared with the AA genotype, the GG genotype was associated with a significantly increased risk of MDD [adjusted odds ratio (aOR), 1.76; 95% confidence interval (CI), 1.05-2.94; p = 0.033]. We found an interaction (p = 0.04) between rs17367504 and exercise, a well-known protective factor for MDD. A substantial increase in the risk of MDD was found among those with GG genotypes who did not exercise (aOR, 2.93; 95% CI, 1.66-5.17; p < 0.001).Our findings indicate that MDD is related to MTHFR rs17367504 and exercise, though the mechanisms remain to be determined." @default.
• W4283207415 created "2022-06-22" @default.
• W4283207415 creator A5003338919 @default.
• W4283207415 creator A5003787049 @default.
• W4283207415 creator A5013496922 @default.
• W4283207415 creator A5024064742 @default.
• W4283207415 creator A5036846752 @default.
• W4283207415 creator A5049847904 @default.
• W4283207415 creator A5085871326 @default.
• W4283207415 creator A5087093115 @default.
• W4283207415 date "2022-06-21" @default.
• W4283207415 modified "2023-09-30" @default.
• W4283207415 title "Association Between MTHFR rs17367504 Polymorphism and Major Depressive Disorder in Taiwan: Evidence for Effect Modification by Exercise Habits" @default.
• W4283207415 cites W1794181152 @default.
• W4283207415 cites W1962454315 @default.
• W4283207415 cites W1965030725 @default.
• W4283207415 cites W1965672724 @default.
• W4283207415 cites W1966251853 @default.
• W4283207415 cites W1976555550 @default.
• W4283207415 cites W1989800882 @default.
• W4283207415 cites W1991015699 @default.
• W4283207415 cites W1996762618 @default.
• W4283207415 cites W2003982930 @default.
• W4283207415 cites W2018614895 @default.
• W4283207415 cites W2019398009 @default.
• W4283207415 cites W2046667801 @default.
• W4283207415 cites W2049065222 @default.
• W4283207415 cites W2049503645 @default.
• W4283207415 cites W2068451584 @default.
• W4283207415 cites W2083020792 @default.
• W4283207415 cites W2090363141 @default.
• W4283207415 cites W2096196173 @default.
• W4283207415 cites W2102622802 @default.
• W4283207415 cites W2105407919 @default.
• W4283207415 cites W2112341251 @default.
• W4283207415 cites W2114894040 @default.
• W4283207415 cites W2129254992 @default.
• W4283207415 cites W2133530258 @default.
• W4283207415 cites W2144891453 @default.
• W4283207415 cites W2153606794 @default.
• W4283207415 cites W2156000458 @default.
• W4283207415 cites W2165715420 @default.
• W4283207415 cites W2171691063 @default.
• W4283207415 cites W2204858842 @default.
• W4283207415 cites W2206994582 @default.
• W4283207415 cites W2219363513 @default.
• W4283207415 cites W2227813149 @default.
• W4283207415 cites W2301412929 @default.
• W4283207415 cites W2324790029 @default.
• W4283207415 cites W2588858982 @default.
• W4283207415 cites W2759089344 @default.
• W4283207415 cites W2800752652 @default.
• W4283207415 cites W2803008851 @default.
• W4283207415 cites W2900262677 @default.
• W4283207415 cites W2913696992 @default.
• W4283207415 cites W2925222320 @default.
• W4283207415 cites W3149749348 @default.
• W4283207415 cites W4211263234 @default.
• W4283207415 cites W92155667 @default.
• W4283207415 doi "https://doi.org/10.3389/fpsyt.2022.821448" @default.
• W4283207415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35800018" @default.
• W4283207415 hasPublicationYear "2022" @default.
• W4283207415 type Work @default.
• W4283207415 citedByCount "0" @default.
• W4283207415 crossrefType "journal-article" @default.
• W4283207415 hasAuthorship W4283207415A5003338919 @default.
• W4283207415 hasAuthorship W4283207415A5003787049 @default.
• W4283207415 hasAuthorship W4283207415A5013496922 @default.
• W4283207415 hasAuthorship W4283207415A5024064742 @default.
• W4283207415 hasAuthorship W4283207415A5036846752 @default.
• W4283207415 hasAuthorship W4283207415A5049847904 @default.
• W4283207415 hasAuthorship W4283207415A5085871326 @default.
• W4283207415 hasAuthorship W4283207415A5087093115 @default.
• W4283207415 hasBestOaLocation W42832074151 @default.
• W4283207415 hasConcept C104317684 @default.
• W4283207415 hasConcept C126322002 @default.
• W4283207415 hasConcept C135763542 @default.
• W4283207415 hasConcept C139719470 @default.
• W4283207415 hasConcept C143998085 @default.
• W4283207415 hasConcept C151956035 @default.
• W4283207415 hasConcept C156957248 @default.
• W4283207415 hasConcept C162324750 @default.
• W4283207415 hasConcept C2776867660 @default.
• W4283207415 hasConcept C2779144063 @default.
• W4283207415 hasConcept C2780051608 @default.
• W4283207415 hasConcept C43563269 @default.
• W4283207415 hasConcept C44249647 @default.
• W4283207415 hasConcept C54355233 @default.
• W4283207415 hasConcept C71924100 @default.
• W4283207415 hasConcept C86803240 @default.
• W4283207415 hasConceptScore W4283207415C104317684 @default.
• W4283207415 hasConceptScore W4283207415C126322002 @default.
• W4283207415 hasConceptScore W4283207415C135763542 @default.
• W4283207415 hasConceptScore W4283207415C139719470 @default.
• W4283207415 hasConceptScore W4283207415C143998085 @default.
• W4283207415 hasConceptScore W4283207415C151956035 @default.
• W4283207415 hasConceptScore W4283207415C156957248 @default.
• W4283207415 hasConceptScore W4283207415C162324750 @default.
• W4283207415 hasConceptScore W4283207415C2776867660 @default.
• W4283207415 hasConceptScore W4283207415C2779144063 @default.

• next