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• W4283208037 abstract "Abstract Periodontitis is a preventable and treatable multifactorial chronic inflammatory disease that can lead to irreversible periodontal destruction and tooth loss. Wnt signaling and its regulators play an important role in periodontal inflammation, destruction, regeneration, and reconstruction. This systematic review aimed at investigating the involvement of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after periodontal treatment. Electronic searches were carried out using MEDLINE/PubMed, EMBASE, and Cochrane Library databases in addition to hand searches. Studies having different designs assessing the levels of Wnt signaling antagonist and agonist levels in gingival crevicular fluid, serum, and tissue in patients diagnosed with periodontitis or gingivitis, compared with healthy individuals were included. In addition, studies compared these levels in periodontitis patients before and after non‐surgical periodontal therapy were also eligible. Sixteen studies met the eligibility criteria. Sclerostin (SOST) has been mainly investigated in the literature (8 publications). Sclerostin (5 studies), Wnt‐5a (2 studies), secreted frizzled‐related protein 1 (SFRP1) (3 studies), and β‐catenin (3 studies) show increased levels in periodontitis compared with periodontal health. Strong correlations between marker levels and periodontal clinical parameters were identified for SOST (5 studies), SFRP1 (2 studies), and β‐catenin (2 studies). SOST (3 studies) and SFRP1 (1 study) levels significantly decrease following non‐surgical periodontal treatment. The present systematic review demonstrated an association between Wnt signaling agonist and antagonist levels and periodontitis. Wnt agonists and antagonists may serve as valuable diagnostic and prognostic markers for periodontitis onset and progression. Further case–control and longitudinal studies should be conducted for different Wnt signaling agonists and antagonists." @default.
• W4283208037 created "2022-06-22" @default.
• W4283208037 creator A5052461059 @default.
• W4283208037 creator A5058610300 @default.
• W4283208037 creator A5077194298 @default.
• W4283208037 date "2022-06-20" @default.
• W4283208037 modified "2023-09-27" @default.
• W4283208037 title "Expression of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after non‐surgical periodontal treatment: A systematic review" @default.
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• W4283208037 cites W1968601496 @default.
• W4283208037 cites W1970596089 @default.
• W4283208037 cites W1991218860 @default.
• W4283208037 cites W1997072139 @default.
• W4283208037 cites W2001812470 @default.
• W4283208037 cites W2003944206 @default.
• W4283208037 cites W2010118143 @default.
• W4283208037 cites W2010710109 @default.
• W4283208037 cites W2017044005 @default.
• W4283208037 cites W2029187758 @default.
• W4283208037 cites W2031611890 @default.
• W4283208037 cites W2033585269 @default.
• W4283208037 cites W2048127493 @default.
• W4283208037 cites W2053735721 @default.
• W4283208037 cites W2055739713 @default.
• W4283208037 cites W2060158738 @default.
• W4283208037 cites W2069543462 @default.
• W4283208037 cites W2087560312 @default.
• W4283208037 cites W2111113377 @default.
• W4283208037 cites W2112432529 @default.
• W4283208037 cites W2119962765 @default.
• W4283208037 cites W2127990872 @default.
• W4283208037 cites W2131801710 @default.
• W4283208037 cites W2135914580 @default.
• W4283208037 cites W2140689100 @default.
• W4283208037 cites W2142083750 @default.
• W4283208037 cites W2145122914 @default.
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• W4283208037 cites W2161052815 @default.
• W4283208037 cites W2164012871 @default.
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• W4283208037 cites W2262950953 @default.
• W4283208037 cites W2269260260 @default.
• W4283208037 cites W2385528667 @default.
• W4283208037 cites W2468996569 @default.
• W4283208037 cites W2531652035 @default.
• W4283208037 cites W2534651070 @default.
• W4283208037 cites W2578450947 @default.
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• W4283208037 cites W2936508908 @default.
• W4283208037 cites W2951313231 @default.
• W4283208037 cites W2970035186 @default.
• W4283208037 cites W2970684805 @default.
• W4283208037 cites W2979486143 @default.
• W4283208037 cites W2988248232 @default.
• W4283208037 cites W2998289360 @default.
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• W4283208037 doi "https://doi.org/10.1111/jre.13029" @default.
• W4283208037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35719081" @default.
• W4283208037 hasPublicationYear "2022" @default.
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