Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283211027> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4283211027 abstract "Human adenovirus type 8 is a highly contagious eye disease and is considered as the most common epidemic keratoconjunctivitis worldwide. The virus may alter the course of detection as mutations and recombination in surface antigens are associated with binding and pathogenesis in human adenovirus. The recognition of new recombinant human adenovirus has been based on sequencing of three genes, penton base, hexon and fiber.50 suspected samples of ocular keratoconjunctivitis were selected over 6 months. Following DNA extraction from isolates positive for cytopathic effect in each well, the complete sequences of hexon, fiber, and penton regions were performed on the genome of human adenovirus isolates using PCR. The sequences of capsid genes, including hexon, fiber, and penton were assessed to observe the evidence of recombination at the molecular level using genetic tools.The results of nucleotide and amino acid sequence of 5/50 patients with epidemic keratoconjunctivitis positive for hypervariable region of hexon (132aa -449), hypervariable of knob fiber (183aa -362) and hypervariable penton (106aa -466) isolates showed nucleotide and amino acid identity of 98% and 99.41%, 99% and 100%, 95% and 99.72% with hexon, fiber and penton of human adenovirus 8 subtypes. The results of phylogenetic tree and Simplot of the entire sequences and hypervariable regions of isolated hexon, fiber and penton showed all the isolates of human adenovirus from Ahvaz, Iran, were clustered with human adenovirus 8A, B, E, P and J, subtypes isolated strains from different regions of the world.The results of this study revealed that the human adenovirus isolates from patients with epidemic keratoconjunctivitis were closed to human adenovirus 8A, B, E, P and J subtypes. To determine the emergence of new human adenovirus D8 subtypes strain, analysis of complete genome sequence of human adenovirus was required." @default.
- W4283211027 created "2022-06-22" @default.
- W4283211027 creator A5001581603 @default.
- W4283211027 creator A5007210146 @default.
- W4283211027 creator A5032145987 @default.
- W4283211027 creator A5033862371 @default.
- W4283211027 creator A5053485292 @default.
- W4283211027 creator A5056450721 @default.
- W4283211027 creator A5065744659 @default.
- W4283211027 creator A5080630944 @default.
- W4283211027 date "2022-06-20" @default.
- W4283211027 modified "2023-10-18" @default.
- W4283211027 title "Evolution and diversity of human adenoviruses isolated from patients with keratoconjunctivitis" @default.
- W4283211027 cites W1966880176 @default.
- W4283211027 cites W1975408822 @default.
- W4283211027 cites W2029412485 @default.
- W4283211027 cites W2047819170 @default.
- W4283211027 cites W2061336937 @default.
- W4283211027 cites W2061803918 @default.
- W4283211027 cites W2092828544 @default.
- W4283211027 cites W2097699811 @default.
- W4283211027 cites W2116770380 @default.
- W4283211027 cites W2123745267 @default.
- W4283211027 cites W2136875106 @default.
- W4283211027 cites W2138583750 @default.
- W4283211027 cites W2143567623 @default.
- W4283211027 cites W2163708786 @default.
- W4283211027 cites W2164944883 @default.
- W4283211027 cites W2282367051 @default.
- W4283211027 cites W2883728346 @default.
- W4283211027 doi "https://doi.org/10.18502/ijm.v14i3.9792" @default.
- W4283211027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37124862" @default.
- W4283211027 hasPublicationYear "2022" @default.
- W4283211027 type Work @default.
- W4283211027 citedByCount "0" @default.
- W4283211027 crossrefType "journal-article" @default.
- W4283211027 hasAuthorship W4283211027A5001581603 @default.
- W4283211027 hasAuthorship W4283211027A5007210146 @default.
- W4283211027 hasAuthorship W4283211027A5032145987 @default.
- W4283211027 hasAuthorship W4283211027A5033862371 @default.
- W4283211027 hasAuthorship W4283211027A5053485292 @default.
- W4283211027 hasAuthorship W4283211027A5056450721 @default.
- W4283211027 hasAuthorship W4283211027A5065744659 @default.
- W4283211027 hasAuthorship W4283211027A5080630944 @default.
- W4283211027 hasBestOaLocation W42832110271 @default.
- W4283211027 hasConcept C104317684 @default.
- W4283211027 hasConcept C159047783 @default.
- W4283211027 hasConcept C193252679 @default.
- W4283211027 hasConcept C202878990 @default.
- W4283211027 hasConcept C2522874641 @default.
- W4283211027 hasConcept C2776954459 @default.
- W4283211027 hasConcept C2777046247 @default.
- W4283211027 hasConcept C40767141 @default.
- W4283211027 hasConcept C49105822 @default.
- W4283211027 hasConcept C54355233 @default.
- W4283211027 hasConcept C81566733 @default.
- W4283211027 hasConcept C84148353 @default.
- W4283211027 hasConcept C86803240 @default.
- W4283211027 hasConceptScore W4283211027C104317684 @default.
- W4283211027 hasConceptScore W4283211027C159047783 @default.
- W4283211027 hasConceptScore W4283211027C193252679 @default.
- W4283211027 hasConceptScore W4283211027C202878990 @default.
- W4283211027 hasConceptScore W4283211027C2522874641 @default.
- W4283211027 hasConceptScore W4283211027C2776954459 @default.
- W4283211027 hasConceptScore W4283211027C2777046247 @default.
- W4283211027 hasConceptScore W4283211027C40767141 @default.
- W4283211027 hasConceptScore W4283211027C49105822 @default.
- W4283211027 hasConceptScore W4283211027C54355233 @default.
- W4283211027 hasConceptScore W4283211027C81566733 @default.
- W4283211027 hasConceptScore W4283211027C84148353 @default.
- W4283211027 hasConceptScore W4283211027C86803240 @default.
- W4283211027 hasLocation W42832110271 @default.
- W4283211027 hasLocation W42832110272 @default.
- W4283211027 hasLocation W42832110273 @default.
- W4283211027 hasOpenAccess W4283211027 @default.
- W4283211027 hasPrimaryLocation W42832110271 @default.
- W4283211027 hasRelatedWork W1982486135 @default.
- W4283211027 hasRelatedWork W1990903257 @default.
- W4283211027 hasRelatedWork W2009639644 @default.
- W4283211027 hasRelatedWork W2046897131 @default.
- W4283211027 hasRelatedWork W2049591560 @default.
- W4283211027 hasRelatedWork W2072032371 @default.
- W4283211027 hasRelatedWork W2089989719 @default.
- W4283211027 hasRelatedWork W2099734134 @default.
- W4283211027 hasRelatedWork W2887601383 @default.
- W4283211027 hasRelatedWork W4251232847 @default.
- W4283211027 isParatext "false" @default.
- W4283211027 isRetracted "false" @default.
- W4283211027 workType "article" @default.