Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283212022> ?p ?o ?g. }
- W4283212022 endingPage "104572" @default.
- W4283212022 startingPage "104572" @default.
- W4283212022 abstract "We have previously demonstrated that Mucosal-Associated Invariant T (MAIT) cells secrete multiple cytokines after exposure to Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever in humans. However, whether cytokine secreting MAIT cells can enhance or attenuate the clinical severity of bacterial infections remain debatable. This study characterizes human MAIT cell functions in subjects participating in a wild-type S. Typhi human challenge model. Here, we found that MAIT cells exhibit distinct functional signatures associated with protection against typhoid fever. We also observed that the cytokine patterns of MAIT cell responses, rather than the average number of cytokines expressed, are more predictive of typhoid fever outcomes. These results might enable us to objectively, based on functional parameters, identify cytokine patterns that may serve as predictive biomarkers during natural infection and vaccination." @default.
- W4283212022 created "2022-06-22" @default.
- W4283212022 creator A5014946608 @default.
- W4283212022 creator A5015402059 @default.
- W4283212022 creator A5023032597 @default.
- W4283212022 creator A5049145301 @default.
- W4283212022 creator A5061528291 @default.
- W4283212022 creator A5065914659 @default.
- W4283212022 creator A5073282795 @default.
- W4283212022 creator A5074270824 @default.
- W4283212022 creator A5077663553 @default.
- W4283212022 creator A5079843231 @default.
- W4283212022 date "2022-08-01" @default.
- W4283212022 modified "2023-10-17" @default.
- W4283212022 title "Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever" @default.
- W4283212022 cites W1487816967 @default.
- W4283212022 cites W1617495083 @default.
- W4283212022 cites W1935043882 @default.
- W4283212022 cites W1968114652 @default.
- W4283212022 cites W1969459508 @default.
- W4283212022 cites W1979468186 @default.
- W4283212022 cites W1982688638 @default.
- W4283212022 cites W1990332769 @default.
- W4283212022 cites W2003222791 @default.
- W4283212022 cites W2003602243 @default.
- W4283212022 cites W2019840235 @default.
- W4283212022 cites W2030655316 @default.
- W4283212022 cites W2031993489 @default.
- W4283212022 cites W2104487243 @default.
- W4283212022 cites W2104960492 @default.
- W4283212022 cites W2110031290 @default.
- W4283212022 cites W2110279664 @default.
- W4283212022 cites W2111641487 @default.
- W4283212022 cites W2123106908 @default.
- W4283212022 cites W2126339385 @default.
- W4283212022 cites W2126813575 @default.
- W4283212022 cites W2138554365 @default.
- W4283212022 cites W2140826226 @default.
- W4283212022 cites W2145188627 @default.
- W4283212022 cites W2274718600 @default.
- W4283212022 cites W2288764509 @default.
- W4283212022 cites W2592582357 @default.
- W4283212022 cites W2605159445 @default.
- W4283212022 cites W2759549847 @default.
- W4283212022 cites W2967959962 @default.
- W4283212022 cites W2990559739 @default.
- W4283212022 cites W3000994048 @default.
- W4283212022 cites W3044339780 @default.
- W4283212022 cites W3048859093 @default.
- W4283212022 cites W3103699740 @default.
- W4283212022 cites W3123017324 @default.
- W4283212022 cites W3127915790 @default.
- W4283212022 cites W3190947740 @default.
- W4283212022 cites W3202554461 @default.
- W4283212022 cites W3204645128 @default.
- W4283212022 cites W4300774608 @default.
- W4283212022 doi "https://doi.org/10.1016/j.cellimm.2022.104572" @default.
- W4283212022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35772315" @default.
- W4283212022 hasPublicationYear "2022" @default.
- W4283212022 type Work @default.
- W4283212022 citedByCount "4" @default.
- W4283212022 countsByYear W42832120222022 @default.
- W4283212022 countsByYear W42832120222023 @default.
- W4283212022 crossrefType "journal-article" @default.
- W4283212022 hasAuthorship W4283212022A5014946608 @default.
- W4283212022 hasAuthorship W4283212022A5015402059 @default.
- W4283212022 hasAuthorship W4283212022A5023032597 @default.
- W4283212022 hasAuthorship W4283212022A5049145301 @default.
- W4283212022 hasAuthorship W4283212022A5061528291 @default.
- W4283212022 hasAuthorship W4283212022A5065914659 @default.
- W4283212022 hasAuthorship W4283212022A5073282795 @default.
- W4283212022 hasAuthorship W4283212022A5074270824 @default.
- W4283212022 hasAuthorship W4283212022A5077663553 @default.
- W4283212022 hasAuthorship W4283212022A5079843231 @default.
- W4283212022 hasBestOaLocation W42832120221 @default.
- W4283212022 hasConcept C104317684 @default.
- W4283212022 hasConcept C159047783 @default.
- W4283212022 hasConcept C203014093 @default.
- W4283212022 hasConcept C22070199 @default.
- W4283212022 hasConcept C2776714567 @default.
- W4283212022 hasConcept C2778690821 @default.
- W4283212022 hasConcept C2779607309 @default.
- W4283212022 hasConcept C2781065037 @default.
- W4283212022 hasConcept C2994552716 @default.
- W4283212022 hasConcept C520601542 @default.
- W4283212022 hasConcept C523546767 @default.
- W4283212022 hasConcept C54355233 @default.
- W4283212022 hasConcept C547475151 @default.
- W4283212022 hasConcept C55493867 @default.
- W4283212022 hasConcept C86803240 @default.
- W4283212022 hasConcept C89423630 @default.
- W4283212022 hasConceptScore W4283212022C104317684 @default.
- W4283212022 hasConceptScore W4283212022C159047783 @default.
- W4283212022 hasConceptScore W4283212022C203014093 @default.
- W4283212022 hasConceptScore W4283212022C22070199 @default.
- W4283212022 hasConceptScore W4283212022C2776714567 @default.
- W4283212022 hasConceptScore W4283212022C2778690821 @default.
- W4283212022 hasConceptScore W4283212022C2779607309 @default.