FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283265132> ?p ?o ?g. }

• W4283265132 endingPage "e052373" @default.
• W4283265132 startingPage "e052373" @default.
• W4283265132 abstract "Objective Investigative studies report contradictory results of the relationship between serum lipid levels and the risk of colorectal cancer (CRC). We conducted a meta-analysis of prospective published studies to clarify the relationship between serum lipid and CRC risk. Design Systematic review and meta-analysis. Data Sources PubMed and Embase from inception until December 2020. Eligibility criteria We considered prospective cohort and case–control studies that evaluated differences in serum lipid levels with the risk of developing CRC. Data extraction and synthesis Two independent reviewers screened and included the studies using standardised electronic data extraction forms. The relative risks of the studies were combined with random-effect and fixed-effect models and were analysed for heterogeneity, publication bias and sensitivity. Results Twenty-four prospective studies, including 4 224 317 individuals with 29 499 CRC cases, were included in the meta-analysis. The total pooled risk ratio (RR) for high vs low concentrations of triglyceride (TG) concentrations was reported at 1.21 (95% CI 1.09 to 1.34; I 2 =46.8%), total cholesterol (TC) was at 1.15 (95% CI 1.08 to 1.22; I 2 =36.8%), high-density lipoprotein cholesterol (HDL-C) was 0.86 (95% CI 0.77 to 0.97; I 2 =28.8%) and low-density lipoprotein cholesterol (LDL-C) was observed at 1.03 (95% CI 0.75 to 1.41; I 2 =69.4%). Conclusions This meta-analysis shows that high levels of serum TG and TC are positively correlated with the incidence rate of CRC, while high levels of serum HDL-C are negatively correlated with CRC incidence rate. Furthermore, no association was found between LDL-C and the risk of developing CRC. Nevertheless, the heterogeneity brought about by comparative methods, demographic differences and pathological differences between the research subjects limits the effectiveness of the overall pooled results." @default.
• W4283265132 created "2022-06-23" @default.
• W4283265132 creator A5003765726 @default.
• W4283265132 creator A5035551308 @default.
• W4283265132 creator A5050301455 @default.
• W4283265132 creator A5071505463 @default.
• W4283265132 creator A5090713571 @default.
• W4283265132 date "2022-06-01" @default.
• W4283265132 modified "2023-10-01" @default.
• W4283265132 title "Relationship between serum lipid level and colorectal cancer: a systemic review and meta-analysis" @default.
• W4283265132 cites W1824801998 @default.
• W4283265132 cites W1920678049 @default.
• W4283265132 cites W1983947649 @default.
• W4283265132 cites W1985142483 @default.
• W4283265132 cites W1986536619 @default.
• W4283265132 cites W1999615507 @default.
• W4283265132 cites W2036875543 @default.
• W4283265132 cites W2041751036 @default.
• W4283265132 cites W2048471397 @default.
• W4283265132 cites W2066810634 @default.
• W4283265132 cites W2067702041 @default.
• W4283265132 cites W2069461560 @default.
• W4283265132 cites W2074587020 @default.
• W4283265132 cites W2076312957 @default.
• W4283265132 cites W2083546456 @default.
• W4283265132 cites W2086909863 @default.
• W4283265132 cites W2107573947 @default.
• W4283265132 cites W2118964315 @default.
• W4283265132 cites W2135361533 @default.
• W4283265132 cites W2138331892 @default.
• W4283265132 cites W2142808344 @default.
• W4283265132 cites W2143681456 @default.
• W4283265132 cites W2149847053 @default.
• W4283265132 cites W2155955426 @default.
• W4283265132 cites W2171370241 @default.
• W4283265132 cites W2189149061 @default.
• W4283265132 cites W2292003680 @default.
• W4283265132 cites W2299840252 @default.
• W4283265132 cites W2304305649 @default.
• W4283265132 cites W2336651787 @default.
• W4283265132 cites W2594373254 @default.
• W4283265132 cites W2598820390 @default.
• W4283265132 cites W2777879075 @default.
• W4283265132 cites W2783917851 @default.
• W4283265132 cites W2897531014 @default.
• W4283265132 cites W2898701282 @default.
• W4283265132 cites W2912647398 @default.
• W4283265132 cites W2955549488 @default.
• W4283265132 cites W2975775173 @default.
• W4283265132 cites W2980433564 @default.
• W4283265132 cites W2981607396 @default.
• W4283265132 cites W2991792334 @default.
• W4283265132 cites W3004642442 @default.
• W4283265132 doi "https://doi.org/10.1136/bmjopen-2021-052373" @default.
• W4283265132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35732386" @default.
• W4283265132 hasPublicationYear "2022" @default.
• W4283265132 type Work @default.
• W4283265132 citedByCount "8" @default.
• W4283265132 countsByYear W42832651322022 @default.
• W4283265132 countsByYear W42832651322023 @default.
• W4283265132 crossrefType "journal-article" @default.
• W4283265132 hasAuthorship W4283265132A5003765726 @default.
• W4283265132 hasAuthorship W4283265132A5035551308 @default.
• W4283265132 hasAuthorship W4283265132A5050301455 @default.
• W4283265132 hasAuthorship W4283265132A5071505463 @default.
• W4283265132 hasAuthorship W4283265132A5090713571 @default.
• W4283265132 hasBestOaLocation W42832651321 @default.
• W4283265132 hasConcept C120665830 @default.
• W4283265132 hasConcept C121332964 @default.
• W4283265132 hasConcept C121608353 @default.
• W4283265132 hasConcept C126322002 @default.
• W4283265132 hasConcept C134018914 @default.
• W4283265132 hasConcept C188816634 @default.
• W4283265132 hasConcept C201903717 @default.
• W4283265132 hasConcept C2778163477 @default.
• W4283265132 hasConcept C2778913445 @default.
• W4283265132 hasConcept C2780439572 @default.
• W4283265132 hasConcept C44249647 @default.
• W4283265132 hasConcept C526805850 @default.
• W4283265132 hasConcept C61511704 @default.
• W4283265132 hasConcept C71924100 @default.
• W4283265132 hasConcept C82789193 @default.
• W4283265132 hasConcept C90924648 @default.
• W4283265132 hasConcept C95190672 @default.
• W4283265132 hasConceptScore W4283265132C120665830 @default.
• W4283265132 hasConceptScore W4283265132C121332964 @default.
• W4283265132 hasConceptScore W4283265132C121608353 @default.
• W4283265132 hasConceptScore W4283265132C126322002 @default.
• W4283265132 hasConceptScore W4283265132C134018914 @default.
• W4283265132 hasConceptScore W4283265132C188816634 @default.
• W4283265132 hasConceptScore W4283265132C201903717 @default.
• W4283265132 hasConceptScore W4283265132C2778163477 @default.
• W4283265132 hasConceptScore W4283265132C2778913445 @default.
• W4283265132 hasConceptScore W4283265132C2780439572 @default.
• W4283265132 hasConceptScore W4283265132C44249647 @default.
• W4283265132 hasConceptScore W4283265132C526805850 @default.
• W4283265132 hasConceptScore W4283265132C61511704 @default.
• W4283265132 hasConceptScore W4283265132C71924100 @default.

• next