Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283277016> ?p ?o ?g. }
- W4283277016 endingPage "132240" @default.
- W4283277016 startingPage "132240" @default.
- W4283277016 abstract "Protein adsorption onto solid surfaces is an immanent and spontaneous phenomenon that occurs in many fundamental biomedical applications. Recent research mainly focuses on collectively measuring the protein behaviors in confined localized nanosensing areas, whereas ignoring the ambient aqueous variation that directly affects protein behavior, such as the hydrogen bonding network in protein-water which serves as a crucial and mutually constrained environment. Herein, we develop a novel dual-phase plasmonic sensing platform with a gold nanopyramid array (GNPA), simultaneously monitoring protein binding at the nanosensing surface and the variation tendency of hydrogen bonding in aqueous solution. Two types of protein adsorption and their solution variation are explored: we first investigate bovine serum albumin (BSA) adsorption and its variation tendency of hydrogen bonding formation and fracture in water. Then we apply the sensing chip to monitor the fibrinogen adsorption and its real-time conversion to fibrin in an in vitro model of simulated blood coagulation, where the synchronous sensing signals of localized surface plasmon resonance (LSPR) and aqueous hydrogen bonding variations are acquired. It helps to reveal the connection between hydrogen bonding variations in protein-water solution and protein adsorption behaviors at the surface, a meaningful finding for comprehending the initiation of abnormal blood coagulation and the related thromboembolism disease. Moreover, the proposed dual-phase sensing strategy opens a new path for a wider variety of applications, ranging from monitoring microenvironmental changes inside the human body to detecting the water contamination or environmental pollutants." @default.
- W4283277016 created "2022-06-23" @default.
- W4283277016 creator A5005128418 @default.
- W4283277016 creator A5018269605 @default.
- W4283277016 creator A5066150509 @default.
- W4283277016 creator A5077242615 @default.
- W4283277016 creator A5081268685 @default.
- W4283277016 date "2022-10-01" @default.
- W4283277016 modified "2023-10-03" @default.
- W4283277016 title "Dual-phase nanoplasmonic sensing platform for monitoring blood protein adsorption and its coagulation in vitro" @default.
- W4283277016 cites W1975870961 @default.
- W4283277016 cites W1985676128 @default.
- W4283277016 cites W1995063875 @default.
- W4283277016 cites W2013154482 @default.
- W4283277016 cites W2015823409 @default.
- W4283277016 cites W2032456809 @default.
- W4283277016 cites W2048595001 @default.
- W4283277016 cites W2052466177 @default.
- W4283277016 cites W2052779722 @default.
- W4283277016 cites W2060259421 @default.
- W4283277016 cites W2075770210 @default.
- W4283277016 cites W2077901720 @default.
- W4283277016 cites W2078091641 @default.
- W4283277016 cites W2151893520 @default.
- W4283277016 cites W2193751742 @default.
- W4283277016 cites W2201558185 @default.
- W4283277016 cites W2339243209 @default.
- W4283277016 cites W2343360984 @default.
- W4283277016 cites W2485687501 @default.
- W4283277016 cites W2519488415 @default.
- W4283277016 cites W2772448909 @default.
- W4283277016 cites W2791322696 @default.
- W4283277016 cites W2791372983 @default.
- W4283277016 cites W2888830029 @default.
- W4283277016 cites W2895167136 @default.
- W4283277016 cites W2898450622 @default.
- W4283277016 cites W2913651994 @default.
- W4283277016 cites W2952534170 @default.
- W4283277016 cites W3015654910 @default.
- W4283277016 cites W3109749760 @default.
- W4283277016 cites W3129066196 @default.
- W4283277016 cites W3155145797 @default.
- W4283277016 cites W3165209306 @default.
- W4283277016 doi "https://doi.org/10.1016/j.snb.2022.132240" @default.
- W4283277016 hasPublicationYear "2022" @default.
- W4283277016 type Work @default.
- W4283277016 citedByCount "1" @default.
- W4283277016 countsByYear W42832770162022 @default.
- W4283277016 crossrefType "journal-article" @default.
- W4283277016 hasAuthorship W4283277016A5005128418 @default.
- W4283277016 hasAuthorship W4283277016A5018269605 @default.
- W4283277016 hasAuthorship W4283277016A5066150509 @default.
- W4283277016 hasAuthorship W4283277016A5077242615 @default.
- W4283277016 hasAuthorship W4283277016A5081268685 @default.
- W4283277016 hasConcept C124952713 @default.
- W4283277016 hasConcept C126322002 @default.
- W4283277016 hasConcept C142362112 @default.
- W4283277016 hasConcept C150394285 @default.
- W4283277016 hasConcept C171250308 @default.
- W4283277016 hasConcept C178790620 @default.
- W4283277016 hasConcept C185592680 @default.
- W4283277016 hasConcept C192562407 @default.
- W4283277016 hasConcept C202751555 @default.
- W4283277016 hasConcept C2778382381 @default.
- W4283277016 hasConcept C2780980858 @default.
- W4283277016 hasConcept C44280652 @default.
- W4283277016 hasConcept C55493867 @default.
- W4283277016 hasConcept C71924100 @default.
- W4283277016 hasConceptScore W4283277016C124952713 @default.
- W4283277016 hasConceptScore W4283277016C126322002 @default.
- W4283277016 hasConceptScore W4283277016C142362112 @default.
- W4283277016 hasConceptScore W4283277016C150394285 @default.
- W4283277016 hasConceptScore W4283277016C171250308 @default.
- W4283277016 hasConceptScore W4283277016C178790620 @default.
- W4283277016 hasConceptScore W4283277016C185592680 @default.
- W4283277016 hasConceptScore W4283277016C192562407 @default.
- W4283277016 hasConceptScore W4283277016C202751555 @default.
- W4283277016 hasConceptScore W4283277016C2778382381 @default.
- W4283277016 hasConceptScore W4283277016C2780980858 @default.
- W4283277016 hasConceptScore W4283277016C44280652 @default.
- W4283277016 hasConceptScore W4283277016C55493867 @default.
- W4283277016 hasConceptScore W4283277016C71924100 @default.
- W4283277016 hasLocation W42832770161 @default.
- W4283277016 hasOpenAccess W4283277016 @default.
- W4283277016 hasPrimaryLocation W42832770161 @default.
- W4283277016 hasRelatedWork W1930805725 @default.
- W4283277016 hasRelatedWork W1989097924 @default.
- W4283277016 hasRelatedWork W2042331602 @default.
- W4283277016 hasRelatedWork W2062202252 @default.
- W4283277016 hasRelatedWork W2168780059 @default.
- W4283277016 hasRelatedWork W2356020885 @default.
- W4283277016 hasRelatedWork W2808780655 @default.
- W4283277016 hasRelatedWork W2899084033 @default.
- W4283277016 hasRelatedWork W2946316715 @default.
- W4283277016 hasRelatedWork W3000789669 @default.
- W4283277016 hasVolume "368" @default.
- W4283277016 isParatext "false" @default.
- W4283277016 isRetracted "false" @default.