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- W4283310905 abstract "Abstract Inflatable penile prosthesis (IPP) placement for erectile dysfunction carries a risk of postoperative infection. This risk can be mitigated with intraoperative irrigation with antibiotic solutions. One such irrigant, chlorhexidine gluconate (CHG), has recently been introduced into the field of urology for IPP surgery. This investigation aimed to construct a Markov Model using established data from literature to define the incremental cost of complications following IPP and the range of infection rates at which CHG could serve as a cost-effective approach. The model produced found the incremental cost of infection/mechanical failure to be several thousand dollars when utilizing standard antibiotic regimens of Rifampin/Gentamicin ($2 483) and Vancomycin/Gentamicin ($3 066). However, if CHG irrigation is utilized instead, cost savings of several hundred to over a thousand dollars are observed, so long as CHG maintains below a 2.8% infection rate. The lower baseline cost and potential for equivalent or superior infection prevention with CHG make it an intriguing option for use in IPP surgeries." @default.
- W4283310905 created "2022-06-24" @default.
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- W4283310905 date "2022-06-23" @default.
- W4283310905 modified "2023-10-16" @default.
- W4283310905 title "Use of Chlorhexidine Gluconate Irrigation Solution to Prevent Postoperative Infection in Inflatable Penile Prosthesis: a Cost-effectiveness Analysis" @default.
- W4283310905 doi "https://doi.org/10.21203/rs.3.rs-1755090/v1" @default.
- W4283310905 hasPublicationYear "2022" @default.
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