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- W4283312500 endingPage "6921" @default.
- W4283312500 startingPage "6921" @default.
- W4283312500 abstract "Neridronate or ((6-amino-1-hydroxy-1-phosphonohexyl) phosphonic acid) is an amino-bisphosphonate (BP) synthetized in Italy in 1986. Bisphosphonates are molecules with a P-C-P bond in their structure that allows strong and selectively binding to hydroxyapatite (HAP) as well as osteoclasts inhibition through different mechanisms of action. Neridronate was initially used to treat Paget disease of the bone, demonstrating effectiveness in reducing bone turnover markers as well as pain. The interesting molecular properties of neridronate foster its wide use in several other conditions, such as osteogenesis imperfecta, and osteoporosis. Thanks to the unique safety and efficacy profile, neridronate has been used in secondary osteoporosis due to genetic, rheumatic, and oncological diseases, including in pediatric patients. In the last decade, this drug has also been studied in chronic musculoskeletal pain conditions, such as algodystrophy, demonstrating effectiveness in improving extraskeletal outcomes. This review highlights historical and clinical insights about the use of neridronate for metabolic bone disorders and musculoskeletal pain conditions." @default.
- W4283312500 created "2022-06-24" @default.
- W4283312500 creator A5052079243 @default.
- W4283312500 creator A5074666735 @default.
- W4283312500 date "2022-06-22" @default.
- W4283312500 modified "2023-09-30" @default.
- W4283312500 title "The Rationale for Using Neridronate in Musculoskeletal Disorders: From Metabolic Bone Diseases to Musculoskeletal Pain" @default.
- W4283312500 cites W127042176 @default.
- W4283312500 cites W1695665874 @default.
- W4283312500 cites W1773216646 @default.
- W4283312500 cites W1795697510 @default.
- W4283312500 cites W1849199576 @default.
- W4283312500 cites W187998424 @default.
- W4283312500 cites W1957756084 @default.
- W4283312500 cites W1962287682 @default.
- W4283312500 cites W1965104197 @default.
- W4283312500 cites W1966694566 @default.
- W4283312500 cites W1968089570 @default.
- W4283312500 cites W1970210484 @default.
- W4283312500 cites W1970270213 @default.
- W4283312500 cites W1972974851 @default.
- W4283312500 cites W1974048878 @default.
- W4283312500 cites W1978228601 @default.
- W4283312500 cites W1981006618 @default.
- W4283312500 cites W1981084939 @default.
- W4283312500 cites W1987341466 @default.
- W4283312500 cites W1989344920 @default.
- W4283312500 cites W1989492043 @default.
- W4283312500 cites W1990205440 @default.
- W4283312500 cites W1991252395 @default.
- W4283312500 cites W1999949526 @default.
- W4283312500 cites W2006021879 @default.
- W4283312500 cites W2008985536 @default.
- W4283312500 cites W2010299814 @default.
- W4283312500 cites W2018777439 @default.
- W4283312500 cites W2024887507 @default.
- W4283312500 cites W2028022155 @default.
- W4283312500 cites W2029483636 @default.
- W4283312500 cites W2031062156 @default.
- W4283312500 cites W2032827014 @default.
- W4283312500 cites W2037333809 @default.
- W4283312500 cites W2045747724 @default.
- W4283312500 cites W2052750693 @default.
- W4283312500 cites W2056019384 @default.
- W4283312500 cites W2057967346 @default.
- W4283312500 cites W2064270795 @default.
- W4283312500 cites W2069063472 @default.
- W4283312500 cites W2080130755 @default.
- W4283312500 cites W2081588688 @default.
- W4283312500 cites W2083126509 @default.
- W4283312500 cites W2084865918 @default.
- W4283312500 cites W2085417458 @default.
- W4283312500 cites W2087770138 @default.
- W4283312500 cites W2089566066 @default.
- W4283312500 cites W2096791952 @default.
- W4283312500 cites W2105511156 @default.
- W4283312500 cites W2105911566 @default.
- W4283312500 cites W2112924165 @default.
- W4283312500 cites W2124166505 @default.
- W4283312500 cites W2124527463 @default.
- W4283312500 cites W2135298952 @default.
- W4283312500 cites W2149321039 @default.
- W4283312500 cites W2154655533 @default.
- W4283312500 cites W2154740406 @default.
- W4283312500 cites W2163776744 @default.
- W4283312500 cites W2167539050 @default.
- W4283312500 cites W2168306615 @default.
- W4283312500 cites W2171601824 @default.
- W4283312500 cites W2289142943 @default.
- W4283312500 cites W2309358629 @default.
- W4283312500 cites W2321227665 @default.
- W4283312500 cites W2411943761 @default.
- W4283312500 cites W2582375913 @default.
- W4283312500 cites W2731725622 @default.
- W4283312500 cites W2770786542 @default.
- W4283312500 cites W2793163159 @default.
- W4283312500 cites W2918668130 @default.
- W4283312500 cites W2944555482 @default.
- W4283312500 cites W2954603811 @default.
- W4283312500 cites W2990391088 @default.
- W4283312500 cites W3014617353 @default.
- W4283312500 cites W3027443472 @default.
- W4283312500 cites W3033333229 @default.
- W4283312500 cites W3087070320 @default.
- W4283312500 cites W3169719147 @default.
- W4283312500 cites W3172062418 @default.
- W4283312500 cites W3176825169 @default.
- W4283312500 cites W4220935369 @default.
- W4283312500 cites W4238430552 @default.
- W4283312500 cites W4247100506 @default.
- W4283312500 cites W4281481033 @default.
- W4283312500 cites W2339811752 @default.
- W4283312500 doi "https://doi.org/10.3390/ijms23136921" @default.
- W4283312500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35805927" @default.
- W4283312500 hasPublicationYear "2022" @default.
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