FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283359618> ?p ?o ?g. }

• W4283359618 endingPage "e0270251" @default.
• W4283359618 startingPage "e0270251" @default.
• W4283359618 abstract "Glioblastoma stem cells (GSCs) are an important subpopulation in glioblastoma, implicated in tumor growth, tumor recurrence, and radiation resistance. Understanding the cellular mechanisms for chemo- and radiation resistance could lead to the development of new therapeutic strategies. Here, we demonstrate that CDC20 promotes resistance to chemotherapy and radiation therapy. CDC20 knockdown does not increase TMZ- and radiation-induced DNA damage, or alter DNA damage repair, but rather promotes cell death through accumulation of the pro-apoptotic protein, Bim. Our results identify a CDC20 signaling pathway that regulates chemo- and radiosensitivity in GSCs, with the potential for CDC20-targeted therapeutic strategies in the treatment of glioblastoma." @default.
• W4283359618 created "2022-06-25" @default.
• W4283359618 creator A5014229974 @default.
• W4283359618 creator A5028100054 @default.
• W4283359618 creator A5040434808 @default.
• W4283359618 creator A5046201532 @default.
• W4283359618 creator A5090367346 @default.
• W4283359618 date "2022-06-23" @default.
• W4283359618 modified "2023-10-18" @default.
• W4283359618 title "CDC20 regulates sensitivity to chemotherapy and radiation in glioblastoma stem cells" @default.
• W4283359618 cites W1752089945 @default.
• W4283359618 cites W1771966825 @default.
• W4283359618 cites W1787257297 @default.
• W4283359618 cites W1969236463 @default.
• W4283359618 cites W1971046933 @default.
• W4283359618 cites W1984168218 @default.
• W4283359618 cites W1986141453 @default.
• W4283359618 cites W1987322786 @default.
• W4283359618 cites W1987522796 @default.
• W4283359618 cites W2001544973 @default.
• W4283359618 cites W2015754166 @default.
• W4283359618 cites W2020261953 @default.
• W4283359618 cites W2020357981 @default.
• W4283359618 cites W2029399678 @default.
• W4283359618 cites W2036044314 @default.
• W4283359618 cites W2038725955 @default.
• W4283359618 cites W2039881995 @default.
• W4283359618 cites W2040458067 @default.
• W4283359618 cites W2060551076 @default.
• W4283359618 cites W2075898750 @default.
• W4283359618 cites W2078510083 @default.
• W4283359618 cites W2096287682 @default.
• W4283359618 cites W2106675906 @default.
• W4283359618 cites W2106845421 @default.
• W4283359618 cites W2130501385 @default.
• W4283359618 cites W2132368293 @default.
• W4283359618 cites W2143869264 @default.
• W4283359618 cites W2165400661 @default.
• W4283359618 cites W2302258827 @default.
• W4283359618 cites W2593219267 @default.
• W4283359618 cites W2622981013 @default.
• W4283359618 cites W2775286316 @default.
• W4283359618 cites W2790555249 @default.
• W4283359618 cites W2792537129 @default.
• W4283359618 doi "https://doi.org/10.1371/journal.pone.0270251" @default.
• W4283359618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35737702" @default.
• W4283359618 hasPublicationYear "2022" @default.
• W4283359618 type Work @default.
• W4283359618 citedByCount "2" @default.
• W4283359618 countsByYear W42833596182023 @default.
• W4283359618 crossrefType "journal-article" @default.
• W4283359618 hasAuthorship W4283359618A5014229974 @default.
• W4283359618 hasAuthorship W4283359618A5028100054 @default.
• W4283359618 hasAuthorship W4283359618A5040434808 @default.
• W4283359618 hasAuthorship W4283359618A5046201532 @default.
• W4283359618 hasAuthorship W4283359618A5090367346 @default.
• W4283359618 hasBestOaLocation W42833596181 @default.
• W4283359618 hasConcept C111337013 @default.
• W4283359618 hasConcept C121332964 @default.
• W4283359618 hasConcept C126322002 @default.
• W4283359618 hasConcept C134935766 @default.
• W4283359618 hasConcept C143425029 @default.
• W4283359618 hasConcept C173396325 @default.
• W4283359618 hasConcept C185544564 @default.
• W4283359618 hasConcept C190283241 @default.
• W4283359618 hasConcept C206684579 @default.
• W4283359618 hasConcept C26114605 @default.
• W4283359618 hasConcept C28328180 @default.
• W4283359618 hasConcept C502942594 @default.
• W4283359618 hasConcept C509974204 @default.
• W4283359618 hasConcept C54355233 @default.
• W4283359618 hasConcept C552990157 @default.
• W4283359618 hasConcept C71924100 @default.
• W4283359618 hasConcept C86803240 @default.
• W4283359618 hasConcept C95444343 @default.
• W4283359618 hasConceptScore W4283359618C111337013 @default.
• W4283359618 hasConceptScore W4283359618C121332964 @default.
• W4283359618 hasConceptScore W4283359618C126322002 @default.
• W4283359618 hasConceptScore W4283359618C134935766 @default.
• W4283359618 hasConceptScore W4283359618C143425029 @default.
• W4283359618 hasConceptScore W4283359618C173396325 @default.
• W4283359618 hasConceptScore W4283359618C185544564 @default.
• W4283359618 hasConceptScore W4283359618C190283241 @default.
• W4283359618 hasConceptScore W4283359618C206684579 @default.
• W4283359618 hasConceptScore W4283359618C26114605 @default.
• W4283359618 hasConceptScore W4283359618C28328180 @default.
• W4283359618 hasConceptScore W4283359618C502942594 @default.
• W4283359618 hasConceptScore W4283359618C509974204 @default.
• W4283359618 hasConceptScore W4283359618C54355233 @default.
• W4283359618 hasConceptScore W4283359618C552990157 @default.
• W4283359618 hasConceptScore W4283359618C71924100 @default.
• W4283359618 hasConceptScore W4283359618C86803240 @default.
• W4283359618 hasConceptScore W4283359618C95444343 @default.
• W4283359618 hasFunder F4320315130 @default.
• W4283359618 hasFunder F4320332161 @default.
• W4283359618 hasIssue "6" @default.
• W4283359618 hasLocation W42833596181 @default.
• W4283359618 hasLocation W42833596182 @default.

• next